3cw2

Crystal structure of the intact archaeal translation initiation factor 2 from Sulfolobus solfataricus .

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

Translation initiation factor 2 subunit gamma

Sulfolobus solfataricus

UniProt Q980A5

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 3 Translation initiation factor 2 subunit alpha × 1 (Q97Z79) Translation initiation factor 2 subunit beta × 1 (Q97W59) 与蛋白数一致
2 蛋白异源复合物 异源复合物 蛋白 3 Translation initiation factor 2 subunit alpha × 1 (Q97Z79) Translation initiation factor 2 subunit beta × 1 (Q97W59) 与蛋白数一致
3 蛋白异源复合物 异源复合物 蛋白 3 Translation initiation factor 2 subunit alpha × 1 (Q97Z79) Translation initiation factor 2 subunit beta × 1 (Q97W59) 与蛋白数一致
4 蛋白异源复合物 异源复合物 蛋白 3 Translation initiation factor 2 subunit alpha × 1 (Q97Z79) Translation initiation factor 2 subunit beta × 1 (Q97W59) 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 IF2G_SULSO
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 1–415; UniProt 1–415 作者链 B; PDB构建体 1–415; UniProt 1–415 作者链 E; PDB构建体 1–415; UniProt 1–415 作者链 F; PDB构建体 1–415; UniProt 1–415

Translation initiation factor 2 subunit alpha

Sulfolobus solfataricus

UniProt Q97Z79

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 3 Translation initiation factor 2 subunit gamma × 1 (Q980A5) Translation initiation factor 2 subunit beta × 1 (Q97W59) 与蛋白数一致
2 蛋白异源复合物 异源复合物 蛋白 3 Translation initiation factor 2 subunit gamma × 1 (Q980A5) Translation initiation factor 2 subunit beta × 1 (Q97W59) 与蛋白数一致
3 蛋白异源复合物 异源复合物 蛋白 3 Translation initiation factor 2 subunit gamma × 1 (Q980A5) Translation initiation factor 2 subunit beta × 1 (Q97W59) 与蛋白数一致
4 蛋白异源复合物 异源复合物 蛋白 3 Translation initiation factor 2 subunit gamma × 1 (Q980A5) Translation initiation factor 2 subunit beta × 1 (Q97W59) 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 IF2A_SULSO
Isoform —
PDB实体 2
链与序列区间 作者链 C; PDB构建体 1–266; UniProt 1–266 作者链 D; PDB构建体 1–266; UniProt 1–266 作者链 G; PDB构建体 1–266; UniProt 1–266 作者链 H; PDB构建体 1–266; UniProt 1–266

Translation initiation factor 2 subunit beta

Sulfolobus solfataricus

UniProt Q97W59

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 3 Translation initiation factor 2 subunit gamma × 1 (Q980A5) Translation initiation factor 2 subunit alpha × 1 (Q97Z79) 与蛋白数一致
2 蛋白异源复合物 异源复合物 蛋白 3 Translation initiation factor 2 subunit gamma × 1 (Q980A5) Translation initiation factor 2 subunit alpha × 1 (Q97Z79) 与蛋白数一致
3 蛋白异源复合物 异源复合物 蛋白 3 Translation initiation factor 2 subunit gamma × 1 (Q980A5) Translation initiation factor 2 subunit alpha × 1 (Q97Z79) 与蛋白数一致
4 蛋白异源复合物 异源复合物 蛋白 3 Translation initiation factor 2 subunit gamma × 1 (Q980A5) Translation initiation factor 2 subunit alpha × 1 (Q97Z79) 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 IF2B_SULSO
Isoform —
PDB实体 3
链与序列区间 作者链 K; PDB构建体 1–139; UniProt 1–139 作者链 L; PDB构建体 1–139; UniProt 1–139 作者链 M; PDB构建体 1–139; UniProt 1–139 作者链 N; PDB构建体 1–139; UniProt 1–139

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id3cw2
沉积日期 deposition_date2008-04-21
结构标题 titleCrystal structure of the intact archaeal translation initiation factor 2 from Sulfolobus solfataricus .
关键词 keywords;AIF2, INTACT AIF2, INITIATION FACTOR 2 ALPHA SUBUNIT, INITIATION FACTOR 2 BETA SUBUNIT, INITIATION FACTOR 2 GAMMA SUBUNIT, INITIATION OF THE TRANSLATION, Initiation factor, Protein biosynthesis, RNA-binding, GTP-binding, Nucleotide-binding, TRANSLATION ;; TRANSLATION
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

3cw2__assembly_3__model_1

Assembly 3 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

3cw2__assembly_3__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

3cw2__assembly_3__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)41.30 Å
Rg(电子密度)41.43 Å
总 Rg41.52 Å
原子数6449
残基数818
排除体积116710 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 3cw2__assembly_1__model_1 trimeric (3) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
2 1 3cw2__assembly_2__model_1 trimeric (3) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
3 1 3cw2__assembly_3__model_1 trimeric (3) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
4 1 3cw2__assembly_4__model_1 trimeric (3) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (3)

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6. 折叠分类 (SCOP + CATH) 48 domains

SCOP 2.08 (24 domains)

结构域编号 domain_idd3cw2a1
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.8 — G proteins
结构域编号 domain_idd3cw2a2
类 Class classb — All beta proteins
折叠类型 Fold foldb.43 — Reductase/isomerase/elongation factor common domain
超家族 Superfamily superfamilyb.43.3 — Translation proteins
家族 Family familyb.43.3.0 — automated matches
结构域编号 domain_idd3cw2a3
类 Class classb — All beta proteins
折叠类型 Fold foldb.44 — Elongation factor/aminomethyltransferase common domain
超家族 Superfamily superfamilyb.44.1 — EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
家族 Family familyb.44.1.0 — automated matches
结构域编号 domain_idd3cw2b1
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.8 — G proteins
结构域编号 domain_idd3cw2b2
类 Class classb — All beta proteins
折叠类型 Fold foldb.43 — Reductase/isomerase/elongation factor common domain
超家族 Superfamily superfamilyb.43.3 — Translation proteins
家族 Family familyb.43.3.0 — automated matches
结构域编号 domain_idd3cw2b3
类 Class classb — All beta proteins
折叠类型 Fold foldb.44 — Elongation factor/aminomethyltransferase common domain
超家族 Superfamily superfamilyb.44.1 — EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
家族 Family familyb.44.1.0 — automated matches
结构域编号 domain_idd3cw2c1
类 Class classb — All beta proteins
折叠类型 Fold foldb.40 — OB-fold
超家族 Superfamily superfamilyb.40.4 — Nucleic acid-binding proteins
家族 Family familyb.40.4.5 — Cold shock DNA-binding domain-like
结构域编号 domain_idd3cw2c2
类 Class classa — All alpha proteins
折叠类型 Fold folda.60 — SAM domain-like
超家族 Superfamily superfamilya.60.14 — eIF2alpha middle domain-like
家族 Family familya.60.14.1 — eIF2alpha middle domain-like
结构域编号 domain_idd3cw2c3
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.58 — Ferredoxin-like
超家族 Superfamily superfamilyd.58.51 — eIF-2-alpha, C-terminal domain
家族 Family familyd.58.51.1 — eIF-2-alpha, C-terminal domain
结构域编号 domain_idd3cw2d1
类 Class classb — All beta proteins
折叠类型 Fold foldb.40 — OB-fold
超家族 Superfamily superfamilyb.40.4 — Nucleic acid-binding proteins
家族 Family familyb.40.4.5 — Cold shock DNA-binding domain-like
结构域编号 domain_idd3cw2d2
类 Class classa — All alpha proteins
折叠类型 Fold folda.60 — SAM domain-like
超家族 Superfamily superfamilya.60.14 — eIF2alpha middle domain-like
家族 Family familya.60.14.1 — eIF2alpha middle domain-like
结构域编号 domain_idd3cw2d3
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.58 — Ferredoxin-like
超家族 Superfamily superfamilyd.58.51 — eIF-2-alpha, C-terminal domain
家族 Family familyd.58.51.1 — eIF-2-alpha, C-terminal domain
结构域编号 domain_idd3cw2e1
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.8 — G proteins
结构域编号 domain_idd3cw2e2
类 Class classb — All beta proteins
折叠类型 Fold foldb.43 — Reductase/isomerase/elongation factor common domain
超家族 Superfamily superfamilyb.43.3 — Translation proteins
家族 Family familyb.43.3.0 — automated matches
结构域编号 domain_idd3cw2e3
类 Class classb — All beta proteins
折叠类型 Fold foldb.44 — Elongation factor/aminomethyltransferase common domain
超家族 Superfamily superfamilyb.44.1 — EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
家族 Family familyb.44.1.0 — automated matches
结构域编号 domain_idd3cw2f1
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.37 — P-loop containing nucleoside triphosphate hydrolases
超家族 Superfamily superfamilyc.37.1 — P-loop containing nucleoside triphosphate hydrolases
家族 Family familyc.37.1.8 — G proteins
结构域编号 domain_idd3cw2f2
类 Class classb — All beta proteins
折叠类型 Fold foldb.43 — Reductase/isomerase/elongation factor common domain
超家族 Superfamily superfamilyb.43.3 — Translation proteins
家族 Family familyb.43.3.0 — automated matches
结构域编号 domain_idd3cw2f3
类 Class classb — All beta proteins
折叠类型 Fold foldb.44 — Elongation factor/aminomethyltransferase common domain
超家族 Superfamily superfamilyb.44.1 — EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
家族 Family familyb.44.1.0 — automated matches
结构域编号 domain_idd3cw2g1
类 Class classb — All beta proteins
折叠类型 Fold foldb.40 — OB-fold
超家族 Superfamily superfamilyb.40.4 — Nucleic acid-binding proteins
家族 Family familyb.40.4.5 — Cold shock DNA-binding domain-like
结构域编号 domain_idd3cw2g2
类 Class classa — All alpha proteins
折叠类型 Fold folda.60 — SAM domain-like
超家族 Superfamily superfamilya.60.14 — eIF2alpha middle domain-like
家族 Family familya.60.14.1 — eIF2alpha middle domain-like
结构域编号 domain_idd3cw2g3
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.58 — Ferredoxin-like
超家族 Superfamily superfamilyd.58.51 — eIF-2-alpha, C-terminal domain
家族 Family familyd.58.51.1 — eIF-2-alpha, C-terminal domain
结构域编号 domain_idd3cw2h1
类 Class classb — All beta proteins
折叠类型 Fold foldb.40 — OB-fold
超家族 Superfamily superfamilyb.40.4 — Nucleic acid-binding proteins
家族 Family familyb.40.4.5 — Cold shock DNA-binding domain-like
结构域编号 domain_idd3cw2h2
类 Class classa — All alpha proteins
折叠类型 Fold folda.60 — SAM domain-like
超家族 Superfamily superfamilya.60.14 — eIF2alpha middle domain-like
家族 Family familya.60.14.1 — eIF2alpha middle domain-like
结构域编号 domain_idd3cw2h3
类 Class classd — Alpha and beta proteins (a+b)
折叠类型 Fold foldd.58 — Ferredoxin-like
超家族 Superfamily superfamilyd.58.51 — eIF-2-alpha, C-terminal domain
家族 Family familyd.58.51.1 — eIF-2-alpha, C-terminal domain

CATH v4.4 (24 domains)

结构域编号 domain_id3cw2A01
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id3cw2A02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily10 — Translation factors
结构域编号 domain_id3cw2A03
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily10 — Translation factors
结构域编号 domain_id3cw2B01
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id3cw2B02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily10 — Translation factors
结构域编号 domain_id3cw2B03
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily10 — Translation factors
结构域编号 domain_id3cw2C01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily140 — Nucleic acid-binding proteins
结构域编号 domain_id3cw2C02
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology150 — DNA polymerase; domain 1
同源超家族 H-superfamily homologous superfamily190 — Translation initiation factor 2; subunit 1; domain 2
结构域编号 domain_id3cw2C03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily1130 — EIF_2_alpha
结构域编号 domain_id3cw2D01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily140 — Nucleic acid-binding proteins
结构域编号 domain_id3cw2D02
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology150 — DNA polymerase; domain 1
同源超家族 H-superfamily homologous superfamily190 — Translation initiation factor 2; subunit 1; domain 2
结构域编号 domain_id3cw2D03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily1130 — EIF_2_alpha
结构域编号 domain_id3cw2E01
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id3cw2E02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily10 — Translation factors
结构域编号 domain_id3cw2E03
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily10 — Translation factors
结构域编号 domain_id3cw2F01
类 Class class3 — Alpha Beta
架构 Architecture architecture40 — 3-Layer(aba) Sandwich
拓扑 Topology topology50 — Rossmann fold
同源超家族 H-superfamily homologous superfamily300 — P-loop containing nucleotide triphosphate hydrolases
结构域编号 domain_id3cw2F02
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily10 — Translation factors
结构域编号 domain_id3cw2F03
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology30 — Elongation Factor Tu (Ef-tu); domain 3
同源超家族 H-superfamily homologous superfamily10 — Translation factors
结构域编号 domain_id3cw2G01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily140 — Nucleic acid-binding proteins
结构域编号 domain_id3cw2G02
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology150 — DNA polymerase; domain 1
同源超家族 H-superfamily homologous superfamily190 — Translation initiation factor 2; subunit 1; domain 2
结构域编号 domain_id3cw2G03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily1130 — EIF_2_alpha
结构域编号 domain_id3cw2H01
类 Class class2 — Mainly Beta
架构 Architecture architecture40 — Beta Barrel
拓扑 Topology topology50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily140 — Nucleic acid-binding proteins
结构域编号 domain_id3cw2H02
类 Class class1 — Mainly Alpha
架构 Architecture architecture10 — Orthogonal Bundle
拓扑 Topology topology150 — DNA polymerase; domain 1
同源超家族 H-superfamily homologous superfamily190 — Translation initiation factor 2; subunit 1; domain 2
结构域编号 domain_id3cw2H03
类 Class class3 — Alpha Beta
架构 Architecture architecture30 — 2-Layer Sandwich
拓扑 Topology topology70 — Alpha-Beta Plaits
同源超家族 H-superfamily homologous superfamily1130 — EIF_2_alpha
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7. 引用文献 (1)