3cw4

Large c-terminal domain of influenza a virus RNA-dependent polymerase PB2

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Polymerase basic protein 2

Influenza A virus

UniProt P03428

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PB2_I34A1
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–225; UniProt 535–759

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id3cw4
Deposition date deposition_date2008-04-21
Structure title titleLarge c-terminal domain of influenza a virus RNA-dependent polymerase PB2
Keywords keywordsRNA polymerase, Mitochondrion, mRNA capping, mRNA processing, Nucleus, Virion, TRANSFERASE; TRANSFERASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

3cw4__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

3cw4__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

3cw4__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)18.22 Å
Rg (electron density)17.01 Å
Total Rg18.19 Å
Atom count1642
Residues208
Excluded volume29455 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 3cw4__assembly_1__model_1 monomeric (1) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 3 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd3cw4a1
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.396 — Influenza virus PB2 '627' domain-like
Superfamily Superfamily superfamilyd.396.1 — Influenza virus PB2 '627' domain-like
Family Family familyd.396.1.0 — automated matches
Domain ID domain_idd3cw4a2
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.361 — PB2 C-terminal domain-like
Superfamily Superfamily superfamilyd.361.1 — PB2 C-terminal domain-like
Family Family familyd.361.1.0 — automated matches

CATH v4.4 (1 domains)

Domain ID domain_id3cw4A02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology30 — Defensin A-like
Homologous superfamily homologous superfamily90 — Polymerase Basic Protein 2, C-terminal domain
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7. Citations (1)