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3hqq

Crystal structure of Leishmania mexicana pyruvate kinase (LmPYK) in complex with Fructose 2,6 bisphosphate

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Pyruvate kinase

Leishmania mexicana

UniProt Q27686

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 4 2,6-di-O-phosphono-beta-D-fructofuranose × 4 Consistent with protein count
2 Protein homooligomer Homooligomer Protein 4 2,6-di-O-phosphono-beta-D-fructofuranose × 4 Consistent with protein count
3 Protein homooligomer Homooligomer Protein 4 2,6-di-O-phosphono-beta-D-fructofuranose × 4 Consistent with protein count
4 Protein homooligomer Homooligomer Protein 4 2,6-di-O-phosphono-beta-D-fructofuranose × 4 Consistent with protein count
5 Protein homooligomer Homooligomer Protein 4 2,6-di-O-phosphono-beta-D-fructofuranose × 4 Consistent with protein count
6 Protein homooligomer Homooligomer Protein 4 2,6-di-O-phosphono-beta-D-fructofuranose × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
3hqp 3hqp 3hqp 3hqp 3hqp 3hqp 3hqp 3hqp 3hqp 3hqp 3hqp 3hqp

16 assemblies; showing the first 12

Homodimer
3hqo 3hqo 3hqo 3hqo

4 assemblies

Homotetramer
1pkl 1pkl 3e0v 3e0v 3e0w 3hqn 3hqq 3hqq 3hqq 3hqq 3hqq 3hqq

19 assemblies; showing the first 12

Other homooligomers

None

Heteromeric or nucleic-acid complex

None

View Construct and Data Evidence
UniProt name KPYK_LEIME
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–499； UniProt 1–499 Author chain B； PDBConstruct 1–499； UniProt 1–499 Author chain C； PDBConstruct 1–499； UniProt 1–499 Author chain D； PDBConstruct 1–499； UniProt 1–499 Author chain E； PDBConstruct 1–499； UniProt 1–499 Author chain F； PDBConstruct 1–499； UniProt 1–499 Author chain G； PDBConstruct 1–499； UniProt 1–499 Author chain H； PDBConstruct 1–499； UniProt 1–499 Author chain I； PDBConstruct 1–499； UniProt 1–499 Author chain J； PDBConstruct 1–499； UniProt 1–499 Author chain K； PDBConstruct 1–499； UniProt 1–499 Author chain L； PDBConstruct 1–499； UniProt 1–499 Author chain M； PDBConstruct 1–499； UniProt 1–499 Author chain N； PDBConstruct 1–499； UniProt 1–499 Author chain O； PDBConstruct 1–499； UniProt 1–499 Author chain P； PDBConstruct 1–499； UniProt 1–499 Author chain Q； PDBConstruct 1–499； UniProt 1–499 Author chain R； PDBConstruct 1–499； UniProt 1–499 Author chain S； PDBConstruct 1–499； UniProt 1–499 Author chain T； PDBConstruct 1–499； UniProt 1–499 Author chain U； PDBConstruct 1–499； UniProt 1–499 Author chain V； PDBConstruct 1–499； UniProt 1–499 Author chain W； PDBConstruct 1–499； UniProt 1–499 Author chain X； PDBConstruct 1–499； UniProt 1–499

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id3hqq
Deposition date deposition_date2009-06-08
Structure title titleCrystal structure of Leishmania mexicana pyruvate kinase (LmPYK) in complex with Fructose 2,6 bisphosphate
Keywords keywordsTIM BARREL, T-STATE ENZYME, Allosteric enzyme, Glycolysis, Kinase, Magnesium, Metal-binding, Pyruvate, Transferase; TRANSFERASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

3hqq__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

3hqq__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

3hqq__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）42.91 Å
Rg (electron density)42.27 Å
Total Rg42.45 Å
Atom count15276
Residues1992
Excluded volume270990 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 3hqq__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 3hqq__assembly_2__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 3hqq__assembly_3__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 3hqq__assembly_4__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
5 1 3hqq__assembly_5__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
6 1 3hqq__assembly_6__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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7. Citations (1)