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3ir2

Crystal structure of the APOBEC3G catalytic domain

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

DNA dC->dU-editing enzyme APOBEC-3G

Homo sapiens

UniProt Q9HC16

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 ZINC ION × 2 CHLORIDE ION × 1 MAGNESIUM ION × 1 water × 1 Consistent with protein count
2 Protein monomer Monomer Protein 1 ZINC ION × 2 CHLORIDE ION × 1 MAGNESIUM ION × 1 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2jyw 2kbo 2kem 3e1u 3iqs 3ir2 3ir2 3v4j 3v4j 4rov 4rov 4row

12 assemblies

Homodimer
3v4j 3v4k 3v4k

3 assemblies

Homotetramer
3v4k 3v4k

2 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
5zva 5zva 5zvb 5zvb 6bwy 6bwy 6bwy 6bwy 6k3j 6k3k 7uxd 8cx0

14 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name ABC3G_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 14–207； UniProt 191–384 Author chain B； PDBConstruct 14–207； UniProt 191–384

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id3ir2
Deposition date deposition_date2009-08-21
Structure title titleCrystal structure of the APOBEC3G catalytic domain
Keywords keywordsAPOBEC3G, ANTIVIRAL DEFENSE, HOST-VIRUS INTERACTION, HYDROLASE, METAL-BINDING, Nucleus; HYDROLASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

3ir2__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

3ir2__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

3ir2__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）17.91 Å
Rg (electron density)16.58 Å
Total Rg17.48 Å
Atom count1504
Residues188
Excluded volume26317 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 3ir2__assembly_1__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 3ir2__assembly_2__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

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6. Fold Classification (SCOP + CATH) 2 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd3ir2a_
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.97 — Cytidine deaminase-like
Superfamily Superfamily superfamilyc.97.1 — Cytidine deaminase-like
Family Family familyc.97.1.6 — apolipoprotein B messenger RNA-editing enzyme catalytic (APOBEC) cytidine deaminase domains
Domain ID domain_idd3ir2b_
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.97 — Cytidine deaminase-like
Superfamily Superfamily superfamilyc.97.1 — Cytidine deaminase-like
Family Family familyc.97.1.6 — apolipoprotein B messenger RNA-editing enzyme catalytic (APOBEC) cytidine deaminase domains
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7. Citations (1)