Escherichia coli
| Assembly | Physical composition | Protein state | Molecular copy count | Associated components | Data consistency |
|---|---|---|---|---|---|
| 1 | Protein monomer | Monomer | Protein 1 | COBALAMIN × 1 water × 1 | Consistent with protein count |
| UniProt name | METH_ECOLI |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–579； UniProt 649–1227 |
The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.
| Entry ID entry_id | 3iv9 |
| Deposition date deposition_date | 2009-08-31 |
| Structure title title | Structure of the B12-dependent Methionine Synthase (MetH) C-teminal half in a "His-On" conformation |
| Keywords keywords | ;METH, transferase, reactivation conformation, H759, cobalamin, intermodular interactions, amino-acid biosynthesis, cobalt, metal-binding, methionine biosynthesis, methyltransferase, S-adenosyl-L-methionine ;; TRANSFERASE |
| Experimental Method method | X-RAY DIFFRACTION |
This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 27.41 Å |
| Rg (electron density) | 26.35 Å |
| Total Rg | 27.01 Å |
| Atom count | 4663 |
| Residues | 577 |
| Excluded volume | 82687 ų |
| Maximum q | 0.500 Å⁻¹ |
| Domain ID domain_id | 3iv9A01 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 10 — Orthogonal Bundle |
| Topology topology | 1240 — Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 |
| Homologous superfamily homologous superfamily | 10 — Methionine synthase domain |
| Domain ID domain_id | 3iv9A02 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 40 — 3-Layer(aba) Sandwich |
| Topology topology | 50 — Rossmann fold |
| Homologous superfamily homologous superfamily | 280 — Cobalamin-binding domain |
| Domain ID domain_id | 3iv9A03 |
| Class class | 3 — Alpha Beta |
| Architecture architecture | 10 — Roll |
| Topology topology | 196 — Cobalamin-dependent Methionine Synthase; domain 1 |
| Homologous superfamily homologous superfamily | 10 — Vitamin B12-dependent methionine synthase, activation domain |
| Domain ID domain_id | 3iv9A04 |
| Class class | 1 — Mainly Alpha |
| Architecture architecture | 10 — Orthogonal Bundle |
| Topology topology | 288 — Cobalamin-dependent Methionine Synthase; domain 2 |
| Homologous superfamily homologous superfamily | 10 — Cobalamin-dependent Methionine Synthase, domain 2 |