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3q0m

Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with p38alpha NREb

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Pumilio homolog 1

Homo sapiens

UniProt Q14671

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Monomer Protein 1 RNA 1 5'-R(UP*GP*UP*AP*GP*AP*UP*A)-3' × 1 water × 2 Consistent with all polymers
2 Protein–RNA Monomer Protein 1 RNA 1 5'-R(UP*GP*UP*AP*GP*AP*UP*A)-3' × 1 water × 2 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer
1ib2 1m8z 3bsb 5ykh

4 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
1m8w 1m8w 1m8x 1m8x 1m8y 1m8y 2yjy 2yjy 3bsb 3bsx 3bsx 3q0l

22 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name PUM1_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–349； UniProt 828–1176 Author chain B； PDBConstruct 1–349； UniProt 828–1176

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id3q0m
Deposition date deposition_date2010-12-15
Structure title titleCrystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with p38alpha NREb
Keywords keywordsPUF, PUMILIO-homolgy domain, Gene regulation, RNA binding, RNA binding protein-RNA complex; RNA binding protein/RNA
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

3q0m__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

3q0m__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

3q0m__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）27.28 Å
Rg (electron density)27.39 Å
Total Rg27.92 Å
Atom count2907
Residues345
Excluded volume51180 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 3q0m__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 3q0m__assembly_2__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd3q0ma_
Class classa — All alpha proteins
Fold Fold folda.118 — alpha-alpha superhelix
Superfamily Superfamily superfamilya.118.1 — ARM repeat
Family Family familya.118.1.8 — Pumilio repeat
Domain ID domain_idd3q0mb_
Class classa — All alpha proteins
Fold Fold folda.118 — alpha-alpha superhelix
Superfamily Superfamily superfamilya.118.1 — ARM repeat
Family Family familya.118.1.8 — Pumilio repeat

CATH v4.4 (2 domains)

Domain ID domain_id3q0mA00
Class class1 — Mainly Alpha
Architecture architecture25 — Alpha Horseshoe
Topology topology10 — Leucine-rich Repeat Variant
Homologous superfamily homologous superfamily10 — Leucine-rich Repeat Variant
Domain ID domain_id3q0mB00
Class class1 — Mainly Alpha
Architecture architecture25 — Alpha Horseshoe
Topology topology10 — Leucine-rich Repeat Variant
Homologous superfamily homologous superfamily10 — Leucine-rich Repeat Variant
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7. Citations (1)