3rl0

Truncated SNARE complex with complexin (P1)

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Vesicle-associated membrane protein 2

Homo sapiens

UniProt P63027

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 5 Syntaxin-1A × 1 (P32851) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Complexin-1 × 1 (O14810) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 5 Syntaxin-1A × 1 (P32851) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Complexin-1 × 1 (O14810) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 5 Syntaxin-1A × 1 (P32851) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Complexin-1 × 1 (O14810) Consistent with protein count
4 Protein heterocomplex Heteromer Protein 5 Syntaxin-1A × 1 (P32851) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Complexin-1 × 1 (O14810) Consistent with protein count
5 Protein heterocomplex Heteromer Protein 5 Syntaxin-1A × 1 (P32851) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Complexin-1 × 1 (O14810) Consistent with protein count
6 Protein heterocomplex Heteromer Protein 5 Syntaxin-1A × 1 (P32851) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Complexin-1 × 1 (O14810) Consistent with protein count
7 Protein heterocomplex Heteromer Protein 5 Syntaxin-1A × 1 (P32851) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Complexin-1 × 1 (O14810) Consistent with protein count
8 Protein heterocomplex Heteromer Protein 5 Syntaxin-1A × 1 (P32851) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Complexin-1 × 1 (O14810) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name VAMP2_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 5–37; UniProt 28–60 Author chain E; PDBConstruct 5–37; UniProt 28–60 Author chain I; PDBConstruct 5–37; UniProt 28–60 Author chain M; PDBConstruct 5–37; UniProt 28–60 Author chain Q; PDBConstruct 5–37; UniProt 28–60 Author chain U; PDBConstruct 5–37; UniProt 28–60 Author chain Y; PDBConstruct 5–37; UniProt 28–60 Author chain c; PDBConstruct 5–37; UniProt 28–60

Syntaxin-1A

Rattus norvegicus

UniProt P32851

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Complexin-1 × 1 (O14810) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Complexin-1 × 1 (O14810) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Complexin-1 × 1 (O14810) Consistent with protein count
4 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Complexin-1 × 1 (O14810) Consistent with protein count
5 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Complexin-1 × 1 (O14810) Consistent with protein count
6 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Complexin-1 × 1 (O14810) Consistent with protein count
7 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Complexin-1 × 1 (O14810) Consistent with protein count
8 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Complexin-1 × 1 (O14810) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name STX1A_RAT
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B; PDBConstruct 3–65; UniProt 191–253 Author chain F; PDBConstruct 3–65; UniProt 191–253 Author chain J; PDBConstruct 3–65; UniProt 191–253 Author chain N; PDBConstruct 3–65; UniProt 191–253 Author chain R; PDBConstruct 3–65; UniProt 191–253 Author chain V; PDBConstruct 3–65; UniProt 191–253 Author chain Z; PDBConstruct 3–65; UniProt 191–253 Author chain d; PDBConstruct 3–65; UniProt 191–253

Synaptosomal-associated protein 25

Homo sapiens

UniProt P60880

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Syntaxin-1A × 1 (P32851) Complexin-1 × 1 (O14810) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Syntaxin-1A × 1 (P32851) Complexin-1 × 1 (O14810) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Syntaxin-1A × 1 (P32851) Complexin-1 × 1 (O14810) Consistent with protein count
4 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Syntaxin-1A × 1 (P32851) Complexin-1 × 1 (O14810) Consistent with protein count
5 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Syntaxin-1A × 1 (P32851) Complexin-1 × 1 (O14810) Consistent with protein count
6 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Syntaxin-1A × 1 (P32851) Complexin-1 × 1 (O14810) Consistent with protein count
7 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Syntaxin-1A × 1 (P32851) Complexin-1 × 1 (O14810) Consistent with protein count
8 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Syntaxin-1A × 1 (P32851) Complexin-1 × 1 (O14810) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name SNP25_HUMAN
Isoform —
PDB entities 3, 4
Chains and sequence ranges Author chain C; PDBConstruct 5–80; UniProt 7–82 Author chain G; PDBConstruct 5–80; UniProt 7–82 Author chain K; PDBConstruct 5–80; UniProt 7–82 Author chain O; PDBConstruct 5–80; UniProt 7–82 Author chain S; PDBConstruct 5–80; UniProt 7–82 Author chain W; PDBConstruct 5–80; UniProt 7–82 Author chain a; PDBConstruct 5–80; UniProt 7–82 Author chain e; PDBConstruct 5–80; UniProt 7–82 Author chain D; PDBConstruct 3–65; UniProt 141–203 Author chain H; PDBConstruct 3–65; UniProt 141–203 Author chain L; PDBConstruct 3–65; UniProt 141–203 Author chain P; PDBConstruct 3–65; UniProt 141–203 Author chain T; PDBConstruct 3–65; UniProt 141–203 Author chain X; PDBConstruct 3–65; UniProt 141–203 Author chain b; PDBConstruct 3–65; UniProt 141–203 Author chain f; PDBConstruct 3–65; UniProt 141–203

Complexin-1

Homo sapiens

UniProt O14810

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Syntaxin-1A × 1 (P32851) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Syntaxin-1A × 1 (P32851) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Syntaxin-1A × 1 (P32851) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Consistent with protein count
4 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Syntaxin-1A × 1 (P32851) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Consistent with protein count
5 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Syntaxin-1A × 1 (P32851) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Consistent with protein count
6 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Syntaxin-1A × 1 (P32851) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Consistent with protein count
7 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Syntaxin-1A × 1 (P32851) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Consistent with protein count
8 Protein heterocomplex Heteromer Protein 5 Vesicle-associated membrane protein 2 × 1 (P63027) Syntaxin-1A × 1 (P32851) Synaptosomal-associated protein 25 × 1 (P60880) Synaptosomal-associated protein 25 × 1 (P60880) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CPLX1_HUMAN
Isoform —
PDB entities 5
Chains and sequence ranges Author chain g; PDBConstruct 6–63; UniProt 26–83 Author chain h; PDBConstruct 6–63; UniProt 26–83 Author chain i; PDBConstruct 6–63; UniProt 26–83 Author chain j; PDBConstruct 6–63; UniProt 26–83 Author chain k; PDBConstruct 6–63; UniProt 26–83 Author chain l; PDBConstruct 6–63; UniProt 26–83 Author chain m; PDBConstruct 6–63; UniProt 26–83 Author chain n; PDBConstruct 6–63; UniProt 26–83

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id3rl0
Deposition date deposition_date2011-04-19
Structure title titleTruncated SNARE complex with complexin (P1)
Keywords keywordsSNARE proteins, membrane fusion, MEMBRANE PROTEIN-EXOCYTOSIS complex; MEMBRANE PROTEIN/EXOCYTOSIS
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

3rl0__assembly_3__model_1

Assembly 3 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

3rl0__assembly_3__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

3rl0__assembly_3__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)28.94 Å
Rg (electron density)29.22 Å
Total Rg29.47 Å
Atom count2209
Residues271
Excluded volume38611 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 3rl0__assembly_1__model_1 pentameric (5) Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 3rl0__assembly_2__model_1 pentameric (5) Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 3rl0__assembly_3__model_1 pentameric (5) Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 3rl0__assembly_4__model_1 pentameric (5) Success 4.1.3-1-20251215 (887e7ef) View Download
5 1 3rl0__assembly_5__model_1 pentameric (5) Success 4.1.3-1-20251215 (887e7ef) View Download
6 1 3rl0__assembly_6__model_1 pentameric (5) Success 4.1.3-1-20251215 (887e7ef) View Download
7 1 3rl0__assembly_7__model_1 pentameric (5) Success 4.1.3-1-20251215 (887e7ef) View Download
8 1 3rl0__assembly_8__model_1 pentameric (5) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

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6. Fold Classification (SCOP + CATH) 32 domains

CATH v4.4 (32 domains)

Domain ID domain_id3rl0B00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0C00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0D00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0F00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0G00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0H00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0J00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0K00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0L00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0N00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0O00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0P00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0R00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0S00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0T00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0V00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0W00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0X00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0Z00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0a00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0b00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0d00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0e00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0f00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily110 —
Domain ID domain_id3rl0g00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily580 — Single Helix bin
Domain ID domain_id3rl0h00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily580 — Single Helix bin
Domain ID domain_id3rl0i00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily580 — Single Helix bin
Domain ID domain_id3rl0j00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily580 — Single Helix bin
Domain ID domain_id3rl0k00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily580 — Single Helix bin
Domain ID domain_id3rl0l00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily580 — Single Helix bin
Domain ID domain_id3rl0m00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily580 — Single Helix bin
Domain ID domain_id3rl0n00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology5 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily580 — Single Helix bin
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7. Citations (1)