3v5i

The crystal structure of the mutant ClpP S98A (Staphylococcus aureus)

Method: X-RAY DIFFRACTION
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

ATP-dependent Clp protease proteolytic subunit

Staphylococcus aureus subsp. aureus

UniProt Q2G036

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白同源多聚体 同源多聚体 蛋白 14 water × 14 与蛋白数一致
2 蛋白同源多聚体 同源多聚体 蛋白 14 water × 14 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 CLPP_STAA8
Isoform —
PDB实体 1
链与序列区间 作者链 A; PDB构建体 1–195; UniProt 1–195 作者链 B; PDB构建体 1–195; UniProt 1–195 作者链 C; PDB构建体 1–195; UniProt 1–195 作者链 D; PDB构建体 1–195; UniProt 1–195 作者链 E; PDB构建体 1–195; UniProt 1–195 作者链 F; PDB构建体 1–195; UniProt 1–195 作者链 G; PDB构建体 1–195; UniProt 1–195 作者链 H; PDB构建体 1–195; UniProt 1–195 作者链 I; PDB构建体 1–195; UniProt 1–195 作者链 J; PDB构建体 1–195; UniProt 1–195 作者链 K; PDB构建体 1–195; UniProt 1–195 作者链 L; PDB构建体 1–195; UniProt 1–195 作者链 M; PDB构建体 1–195; UniProt 1–195 作者链 N; PDB构建体 1–195; UniProt 1–195 作者链 O; PDB构建体 1–195; UniProt 1–195 作者链 P; PDB构建体 1–195; UniProt 1–195 作者链 Q; PDB构建体 1–195; UniProt 1–195 作者链 R; PDB构建体 1–195; UniProt 1–195 作者链 S; PDB构建体 1–195; UniProt 1–195 作者链 T; PDB构建体 1–195; UniProt 1–195 作者链 U; PDB构建体 1–195; UniProt 1–195 作者链 V; PDB构建体 1–195; UniProt 1–195 作者链 W; PDB构建体 1–195; UniProt 1–195 作者链 X; PDB构建体 1–195; UniProt 1–195 作者链 Y; PDB构建体 1–195; UniProt 1–195 作者链 Z; PDB构建体 1–195; UniProt 1–195 作者链 a; PDB构建体 1–195; UniProt 1–195 作者链 b; PDB构建体 1–195; UniProt 1–195

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id3v5i
沉积日期 deposition_date2011-12-16
结构标题 titleThe crystal structure of the mutant ClpP S98A (Staphylococcus aureus)
关键词 keywordsHydrolase, whole proteome; HYDROLASE
实验方法 methodX-RAY DIFFRACTION
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

3v5i__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

3v5i__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

3v5i__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)43.54 Å
Rg(电子密度)42.61 Å
总 Rg43.04 Å
原子数19894
残基数2576
排除体积355840 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 3v5i__assembly_1__model_1 tetradecameric (14) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
2 1 3v5i__assembly_2__model_1 tetradecameric (14) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (2)

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6. 折叠分类 (SCOP + CATH) 54 domains

SCOP 2.08 (26 domains)

结构域编号 domain_idd3v5ia_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5ib_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5ic_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5id_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5ie_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5if_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5ig_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5ih_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5ii_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5ij_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5ik_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5il_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5im_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5in_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5io_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5ip_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5iq_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5ir_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5is_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5it_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5iu_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5iv_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5iw_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5ix_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5iy_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit
结构域编号 domain_idd3v5iz_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.14 — ClpP/crotonase
超家族 Superfamily superfamilyc.14.1 — ClpP/crotonase
家族 Family familyc.14.1.1 — Clp protease, ClpP subunit

CATH v4.4 (28 domains)

结构域编号 domain_id3v5iA00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iB00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iC00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iD00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iE00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iF00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iG00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iH00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iI00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iJ00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iK00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iL00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iM00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iN00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iO00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iP00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iQ00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iR00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iS00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iT00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iU00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iV00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iW00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iX00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iY00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5iZ00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5ia00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
结构域编号 domain_id3v5ib00
类 Class class3 — Alpha Beta
架构 Architecture architecture90 — Alpha-Beta Complex
拓扑 Topology topology226 — 2-enoyl-CoA Hydratase; Chain A, domain 1
同源超家族 H-superfamily homologous superfamily10 — 2-enoyl-CoA Hydratase; Chain A, domain 1
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7. 引用文献 (1)