4cdi

Crystal structure of AcrB-AcrZ complex

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

ACRIFLAVINE RESISTANCE PROTEIN B

ESCHERICHIA COLI

UniProt P31224

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 6 PREDICTED PROTEIN × 3 (C4ZXT3) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name ACRB_ECOLI
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–1049; UniProt 1–1049

PREDICTED PROTEIN

ESCHERICHIA COLI

UniProt C4ZXT3

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 6 ACRIFLAVINE RESISTANCE PROTEIN B × 3 (P31224) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name C4ZXT3_ECOBW
Isoform —
PDB entities 2
Chains and sequence ranges Author chain C; PDBConstruct 1–49; UniProt 1–49

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id4cdi
Deposition date deposition_date2013-10-31
Structure title titleCrystal structure of AcrB-AcrZ complex
Keywords keywordsMEMBRANE PROTEIN, DRUG EFFLUX, TRANSMEMBRANE PROTEIN; MEMBRANE PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

4cdi__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

4cdi__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

4cdi__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)46.58 Å
Rg (electron density)45.88 Å
Total Rg46.15 Å
Atom count24342
Residues3234
Excluded volume440160 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 4cdi__assembly_1__model_1 hexameric (6) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 9 domains

CATH v4.4 (9 domains)

Domain ID domain_id4cdiA01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1640 — Multidrug efflux transporter AcrB transmembrane fold
Homologous superfamily homologous superfamily10 — Multidrug efflux transporter AcrB transmembrane domain
Domain ID domain_id4cdiA02
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily1430 — Multidrug efflux transporter AcrB pore domain
Domain ID domain_id4cdiA03
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily1320 — Multidrug efflux transporter AcrB pore domain like
Domain ID domain_id4cdiA04
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology2090 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Homologous superfamily homologous superfamily10 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Domain ID domain_id4cdiA05
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1640 — Multidrug efflux transporter AcrB transmembrane fold
Homologous superfamily homologous superfamily10 — Multidrug efflux transporter AcrB transmembrane domain
Domain ID domain_id4cdiA06
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily1430 — Multidrug efflux transporter AcrB pore domain
Domain ID domain_id4cdiA07
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily1440 — Multidrug efflux transporter AcrB pore domain
Domain ID domain_id4cdiA08
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology2090 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Homologous superfamily homologous superfamily10 — Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Domain ID domain_id4cdiC00
Class class6 — Special
Architecture architecture10 — Helix non-globular
Topology topology250 — Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous superfamily homologous superfamily2480 —
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7. Citations (1)