← Back to search
4gjg

Crystal structure of the amino-terminal domain of human cardiac troponin C mutant D2N/V28I/L29Q/G30D (NIQD) in complex with cadmium.

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Troponin C, slow skeletal and cardiac muscles

Homo sapiens

UniProt P63316

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 CADMIUM ION × 7 CALCIUM ION × 3 ACETATE ION × 1 GLYCEROL × 1 water × 1 Consistent with protein count
2 Protein homooligomer Homooligomer Protein 2 CADMIUM ION × 14 CALCIUM ION × 6 ACETATE ION × 2 GLYCEROL × 2 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1ap4 1ih0 1spy 2jt0 2jt3 2jt8 2jtz 2jxl 2kdh 2kfx 2l98 2mle

23 assemblies; showing the first 12

Homodimer
1wrk 1wrl 1wrl 1wrl 4gje 4gjf 4gjg

7 assemblies

Homotetramer

None

Other homooligomers
3rv5

1 assemblies

Heteromeric or nucleic-acid complex
1j1d 1j1d 1j1e 1j1e 1lxf 1mxl 1ozs 2kgb 2krd 2l1r 2mkp 2mzp

49 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name TNNC1_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–89； UniProt 1–89

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id4gjg
Deposition date deposition_date2012-08-09
Structure title titleCrystal structure of the amino-terminal domain of human cardiac troponin C mutant D2N/V28I/L29Q/G30D (NIQD) in complex with cadmium.
Keywords keywordsHELIX-LOOP-HELIX EF-HAND MOTIF, CONTRACTILE PROTEIN, CALCIUM SENSOR, CADMIUM BINDING; CONTRACTILE PROTEIN
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

4gjg__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

4gjg__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

4gjg__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）13.67 Å
Rg (electron density)12.34 Å
Total Rg13.59 Å
Atom count693
Residues86
Excluded volume12534 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 4gjg__assembly_1__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 4gjg__assembly_2__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (6)

▼

6. Fold Classification (SCOP + CATH) 1 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd4gjga_
Class classa — All alpha proteins
Fold Fold folda.39 — EF Hand-like
Superfamily Superfamily superfamilya.39.1 — EF-hand
Family Family familya.39.1.5 — Calmodulin-like
▶

7. Citations (1)