4hqp

Alpha7 nicotinic receptor chimera and its complex with Alpha bungarotoxin

Method: X-RAY DIFFRACTION
▼

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Alpha-bungarotoxin isoform V31

物种未注明

UniProt P60616

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 其他组合 异源复合物 蛋白 10 其他聚合物 1 Alpha7 nicotinic receptor chimera × 5 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose × 1 2-acetamido-2-deoxy-beta-D-glucopyranose × 6 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 NXL1V_BUNMU
Isoform —
PDB实体 2
链与序列区间 作者链 F; PDB构建体 1–73; UniProt 22–94 作者链 G; PDB构建体 1–73; UniProt 22–94 作者链 H; PDB构建体 1–73; UniProt 22–94 作者链 I; PDB构建体 1–73; UniProt 22–94 作者链 J; PDB构建体 1–73; UniProt 22–94

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

▼

2. 结构基本信息 2. Structure Basics

条目编号 entry_id4hqp
沉积日期 deposition_date2012-10-25
结构标题 titleAlpha7 nicotinic receptor chimera and its complex with Alpha bungarotoxin
关键词 keywordsProtein-protein Complex, nicotinic receptor, Membrane, nAChR, a-bungarotoxin, PROTEIN BINDING; PROTEIN BINDING
实验方法 methodX-RAY DIFFRACTION
▼

3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

4hqp__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

4hqp__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

4hqp__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)37.07 Å
Rg(电子密度)35.70 Å
总 Rg36.63 Å
原子数11092
残基数1375
排除体积197570 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 4hqp__assembly_1__model_1 decameric (10) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
▶

4. 晶体学与实验 4. Crystallography & Experiment

▶

5. 实体与聚合物信息 Entities & Polymers (4)

▼

6. 折叠分类 (SCOP + CATH) 10 domains

CATH v4.4 (10 domains)

结构域编号 domain_id4hqpA00
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology170 — Acetylcholine Binding Protein; Chain: A,
同源超家族 H-superfamily homologous superfamily10 — Neurotransmitter-gated ion-channel ligand-binding domain
结构域编号 domain_id4hqpB00
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology170 — Acetylcholine Binding Protein; Chain: A,
同源超家族 H-superfamily homologous superfamily10 — Neurotransmitter-gated ion-channel ligand-binding domain
结构域编号 domain_id4hqpC00
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology170 — Acetylcholine Binding Protein; Chain: A,
同源超家族 H-superfamily homologous superfamily10 — Neurotransmitter-gated ion-channel ligand-binding domain
结构域编号 domain_id4hqpD00
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology170 — Acetylcholine Binding Protein; Chain: A,
同源超家族 H-superfamily homologous superfamily10 — Neurotransmitter-gated ion-channel ligand-binding domain
结构域编号 domain_id4hqpE00
类 Class class2 — Mainly Beta
架构 Architecture architecture70 — Distorted Sandwich
拓扑 Topology topology170 — Acetylcholine Binding Protein; Chain: A,
同源超家族 H-superfamily homologous superfamily10 — Neurotransmitter-gated ion-channel ligand-binding domain
结构域编号 domain_id4hqpF00
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology60 — CD59
同源超家族 H-superfamily homologous superfamily10 — CD59
结构域编号 domain_id4hqpG00
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology60 — CD59
同源超家族 H-superfamily homologous superfamily10 — CD59
结构域编号 domain_id4hqpH00
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology60 — CD59
同源超家族 H-superfamily homologous superfamily10 — CD59
结构域编号 domain_id4hqpI00
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology60 — CD59
同源超家族 H-superfamily homologous superfamily10 — CD59
结构域编号 domain_id4hqpJ00
类 Class class2 — Mainly Beta
架构 Architecture architecture10 — Ribbon
拓扑 Topology topology60 — CD59
同源超家族 H-superfamily homologous superfamily10 — CD59
▶

7. 引用文献 (1)