4nrv

Crystal Structure of non-edited human NEIL1

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Endonuclease 8-like 1

Homo sapiens

UniProt Q96FI4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL × 1 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name NEIL1_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–289; UniProt 2–290

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id4nrv
Deposition date deposition_date2013-11-27
Structure title titleCrystal Structure of non-edited human NEIL1
Keywords keywordszincless finger domain, DNA glycosylase, Helix two-turns helix motif, HYDROLASE, LYASE; HYDROLASE, LYASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

4nrv__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

4nrv__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

4nrv__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)21.88 Å
Rg (electron density)21.08 Å
Total Rg21.97 Å
Atom count2196
Residues283
Excluded volume39015 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 4nrv__assembly_1__model_1 monomeric (1) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 5 domains

SCOP 2.08 (3 domains)

Domain ID domain_idd4nrva1
Class classb — All beta proteins
Fold Fold foldb.113 — N-terminal domain of MutM-like DNA repair proteins
Superfamily Superfamily superfamilyb.113.1 — N-terminal domain of MutM-like DNA repair proteins
Family Family familyb.113.1.1 — N-terminal domain of MutM-like DNA repair proteins
Domain ID domain_idd4nrva2
Class classa — All alpha proteins
Fold Fold folda.156 — S13-like H2TH domain
Superfamily Superfamily superfamilya.156.1 — S13-like H2TH domain
Family Family familya.156.1.0 — automated matches
Domain ID domain_idd4nrva3
Class classg — Small proteins
Fold Fold foldg.39 — Glucocorticoid receptor-like (DNA-binding domain)
Superfamily Superfamily superfamilyg.39.1 — Glucocorticoid receptor-like (DNA-binding domain)
Family Family familyg.39.1.0 — automated matches

CATH v4.4 (2 domains)

Domain ID domain_id4nrvA01
Class class3 — Alpha Beta
Architecture architecture20 — Alpha-Beta Barrel
Topology topology190 — N-terminal domain of MutM-like DNA repair proteins
Homologous superfamily homologous superfamily10 — MutM-like, N-terminal
Domain ID domain_id4nrvA02
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology8 — Helicase, Ruva Protein; domain 3
Homologous superfamily homologous superfamily50 —
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7. Citations (1)