Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白同源多聚体 | 同源多聚体 | 蛋白 2 | 无其他共同聚合物 | 与蛋白数一致 |
| 2 | 蛋白同源多聚体 | 同源多聚体 | 蛋白 2 | 无其他共同聚合物 | 与蛋白数一致 |
| UniProt名称 | FAK1_HUMAN |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 2–376； UniProt 31–405 作者链 B； PDB构建体 2–376； UniProt 31–405 作者链 C； PDB构建体 2–376； UniProt 31–405 作者链 D； PDB构建体 2–376； UniProt 31–405 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 4ny0 |
| 沉积日期 deposition_date | 2013-12-10 |
| 结构标题 title | Crystal structure of FERM domain of human focal adhesion kinase |
| 关键词 keywords | FERM domain, focal adhesion kinase, focal targeting domain, integrin signaling, TRANSFERASE; TRANSFERASE |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 30.50 Å |
| Rg（电子密度） | 30.01 Å |
| 总 Rg | 30.76 Å |
| 原子数 | 5336 |
| 残基数 | 658 |
| 排除体积 | 95324 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d4ny0a1 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.15 — beta-Grasp (ubiquitin-like) |
| 超家族 Superfamily superfamily | d.15.1 — Ubiquitin-like |
| 家族 Family family | d.15.1.0 — automated matches |
| 结构域编号 domain_id | d4ny0a2 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.11 — Acyl-CoA binding protein-like |
| 超家族 Superfamily superfamily | a.11.2 — Second domain of FERM |
| 家族 Family family | a.11.2.0 — automated matches |
| 结构域编号 domain_id | d4ny0a3 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.55 — PH domain-like barrel |
| 超家族 Superfamily superfamily | b.55.1 — PH domain-like |
| 家族 Family family | b.55.1.0 — automated matches |
| 结构域编号 domain_id | d4ny0b1 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.15 — beta-Grasp (ubiquitin-like) |
| 超家族 Superfamily superfamily | d.15.1 — Ubiquitin-like |
| 家族 Family family | d.15.1.0 — automated matches |
| 结构域编号 domain_id | d4ny0b2 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.11 — Acyl-CoA binding protein-like |
| 超家族 Superfamily superfamily | a.11.2 — Second domain of FERM |
| 家族 Family family | a.11.2.0 — automated matches |
| 结构域编号 domain_id | d4ny0b3 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.55 — PH domain-like barrel |
| 超家族 Superfamily superfamily | b.55.1 — PH domain-like |
| 家族 Family family | b.55.1.0 — automated matches |
| 结构域编号 domain_id | d4ny0d1 |
| 类 Class class | d — Alpha and beta proteins (a+b) |
| 折叠类型 Fold fold | d.15 — beta-Grasp (ubiquitin-like) |
| 超家族 Superfamily superfamily | d.15.1 — Ubiquitin-like |
| 家族 Family family | d.15.1.0 — automated matches |
| 结构域编号 domain_id | d4ny0d2 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.11 — Acyl-CoA binding protein-like |
| 超家族 Superfamily superfamily | a.11.2 — Second domain of FERM |
| 家族 Family family | a.11.2.0 — automated matches |
| 结构域编号 domain_id | d4ny0d3 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.55 — PH domain-like barrel |
| 超家族 Superfamily superfamily | b.55.1 — PH domain-like |
| 家族 Family family | b.55.1.0 — automated matches |
| 结构域编号 domain_id | 4ny0A01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 10 — Roll |
| 拓扑 Topology topology | 20 — Ubiquitin-like (UB roll) |
| 同源超家族 H-superfamily homologous superfamily | 90 — Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 |
| 结构域编号 domain_id | 4ny0A02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 80 — Acyl-CoA Binding Protein |
| 同源超家族 H-superfamily homologous superfamily | 10 — |
| 结构域编号 domain_id | 4ny0A03 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 30 — Roll |
| 拓扑 Topology topology | 29 — PH-domain like |
| 同源超家族 H-superfamily homologous superfamily | 30 — Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
| 结构域编号 domain_id | 4ny0B01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 10 — Roll |
| 拓扑 Topology topology | 20 — Ubiquitin-like (UB roll) |
| 同源超家族 H-superfamily homologous superfamily | 90 — Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 |
| 结构域编号 domain_id | 4ny0B02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 80 — Acyl-CoA Binding Protein |
| 同源超家族 H-superfamily homologous superfamily | 10 — |
| 结构域编号 domain_id | 4ny0B03 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 30 — Roll |
| 拓扑 Topology topology | 29 — PH-domain like |
| 同源超家族 H-superfamily homologous superfamily | 30 — Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
| 结构域编号 domain_id | 4ny0C01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 10 — Roll |
| 拓扑 Topology topology | 20 — Ubiquitin-like (UB roll) |
| 同源超家族 H-superfamily homologous superfamily | 90 — Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 |
| 结构域编号 domain_id | 4ny0C02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 80 — Acyl-CoA Binding Protein |
| 同源超家族 H-superfamily homologous superfamily | 10 — |
| 结构域编号 domain_id | 4ny0C03 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 30 — Roll |
| 拓扑 Topology topology | 29 — PH-domain like |
| 同源超家族 H-superfamily homologous superfamily | 30 — Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
| 结构域编号 domain_id | 4ny0D01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 10 — Roll |
| 拓扑 Topology topology | 20 — Ubiquitin-like (UB roll) |
| 同源超家族 H-superfamily homologous superfamily | 90 — Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 |
| 结构域编号 domain_id | 4ny0D02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 20 — Up-down Bundle |
| 拓扑 Topology topology | 80 — Acyl-CoA Binding Protein |
| 同源超家族 H-superfamily homologous superfamily | 10 — |
| 结构域编号 domain_id | 4ny0D03 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 30 — Roll |
| 拓扑 Topology topology | 29 — PH-domain like |
| 同源超家族 H-superfamily homologous superfamily | 30 — Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |