Homo sapiens
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白同源多聚体 | 同源多聚体 | 蛋白 2 | PHOSPHATE ION × 3 3-{[(2,4-diaminoquinazolin-5-yl)oxy]methyl}benzenesulfonic acid × 1 | 与蛋白数一致 |
| 2 | 蛋白同源多聚体 | 同源多聚体 | 蛋白 2 | PHOSPHATE ION × 1 | 与蛋白数一致 |
| UniProt名称 | DCPS_HUMAN |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 2–337； UniProt 2–337 作者链 B； PDB构建体 2–337； UniProt 2–337 作者链 C； PDB构建体 2–337； UniProt 2–337 作者链 D； PDB构建体 2–337； UniProt 2–337 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 4qeb |
| 沉积日期 deposition_date | 2014-05-15 |
| 结构标题 title | Dcps in complex with covalent inhibitor targeting Tyrosine |
| 关键词 keywords | ;Decapping scavenger enzyme, residual cap structure cleavage, mRNA degradation, 3'->5' exosome-mediated mRNA decay pathway, HYDROLASE-HYDROLASE INHIBITOR complex ;; HYDROLASE/HYDROLASE INHIBITOR |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 26.23 Å |
| Rg（电子密度） | 25.12 Å |
| 总 Rg | 26.01 Å |
| 原子数 | 4812 |
| 残基数 | 575 |
| 排除体积 | 85346 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | 4qebA01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 200 — Phosphorylase Kinase; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 40 — Scavenger mRNA decapping enzyme, N-terminal domain |
| 结构域编号 domain_id | 4qebA02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 428 — HIT family, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 10 — HIT-like |
| 结构域编号 domain_id | 4qebB01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 200 — Phosphorylase Kinase; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 40 — Scavenger mRNA decapping enzyme, N-terminal domain |
| 结构域编号 domain_id | 4qebB02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 2240 — mRNA decapping enzyme DcpS N-terminal fold |
| 同源超家族 H-superfamily homologous superfamily | 10 — mRNA decapping enzyme DcpS N-terminal domain |
| 结构域编号 domain_id | 4qebB03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 428 — HIT family, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 10 — HIT-like |
| 结构域编号 domain_id | 4qebC01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 200 — Phosphorylase Kinase; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 40 — Scavenger mRNA decapping enzyme, N-terminal domain |
| 结构域编号 domain_id | 4qebC02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 2240 — mRNA decapping enzyme DcpS N-terminal fold |
| 同源超家族 H-superfamily homologous superfamily | 10 — mRNA decapping enzyme DcpS N-terminal domain |
| 结构域编号 domain_id | 4qebC03 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 428 — HIT family, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 10 — HIT-like |
| 结构域编号 domain_id | 4qebD01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 200 — Phosphorylase Kinase; domain 1 |
| 同源超家族 H-superfamily homologous superfamily | 40 — Scavenger mRNA decapping enzyme, N-terminal domain |
| 结构域编号 domain_id | 4qebD02 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 30 — 2-Layer Sandwich |
| 拓扑 Topology topology | 428 — HIT family, subunit A |
| 同源超家族 H-superfamily homologous superfamily | 10 — HIT-like |