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4qvf

Crystal structure of Bcl-xL in complex with BIM BH3 domain

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Bcl-2-like protein 1

Homo sapiens

UniProt Q07817

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Peptide from Bcl-2-like protein 11 × 1 （O43521） water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1lxl 1maz 1r2d 1r2e 1r2g 1r2h 1r2i 1ysg 1ysi 1ysn 2lpc 2m03

41 assemblies; showing the first 12

Homodimer
2b48 3inq 3wiz 3zlr 4c52 4cin 4cin 4qvx 4tuh 4tuh 4tuh 4tuh

33 assemblies; showing the first 12

Homotetramer
4c5d

1 assemblies

Other homooligomers
4ppi

1 assemblies

Heteromeric or nucleic-acid complex
1bxl 1g5j 1g5m 1gjh 2lp8 2m04 2mej 2o21 2o22 2p1l 2p1l 2p1l

120 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name B2CL1_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–169； UniProt 1–209

Peptide from Bcl-2-like protein 11

OrganismNot specified

UniProt O43521

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Bcl-2-like protein 1 × 1 （Q07817） water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer
6x8o

1 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
1f95 2k7w 2nl9 2nl9 2nl9 2v6q 2vm6 2wh6 2yq6 2yq7 3d7v 3fdl

49 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name B2L11_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–26； UniProt 141–166

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id4qvf
Deposition date deposition_date2014-07-15
Structure title titleCrystal structure of Bcl-xL in complex with BIM BH3 domain
Keywords keywordsProtein-peptide complex, Bcl-2 like, Heterodimer, Apoptosis, Anti-apoptotic, BH3 binding, BIM BH3; APOPTOSIS
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

4qvf__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

4qvf__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

4qvf__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）16.19 Å
Rg (electron density)14.61 Å
Total Rg15.80 Å
Atom count1327
Residues162
Excluded volume23391 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 4qvf__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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7. Citations (1)