SAXSdb — 4usg

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1. Protein Identity and Related Structures Protein Identity & Related Structures

ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15

HOMO SAPIENS

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–DNA	Homooligomer	Protein 2 DNA 1	;5'-D(TPTPTPTPTPTPTPTPTPTPTPTPTPTP TPTPTPTPTPG)-3' ; × 1 water × 3	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	TCP4_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 2–66； UniProt 63–127 Author chain B； PDBConstruct 2–66； UniProt 63–127

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	4usg
Deposition date deposition_date	2014-07-08
Structure title title	Crystal structure of PC4 W89Y mutant complex with DNA
Keywords keywords	TRANSCRIPTION; TRANSCRIPTION
Experimental Method method	X-RAY DIFFRACTION

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

4usg__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

4usg__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

4usg__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	16.65 Å
Rg (electron density)	15.50 Å
Total Rg	16.51 Å
Atom count	1366
Residues	146
Excluded volume	23840 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`4usg__assembly_1__model_1`	trimeric （3）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Description description	ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15
Molecular weight formula_weight	7761.0 kDa
Mutation mutation	YES
Source method src_method	man
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B
Atom count atom_count	1494

AMFQIGKMRYVSVRDFKGKVLIDIREYYMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL

Source Source

Source organism organism	HOMO SAPIENS
Common name common_name	HUMAN
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	ESCHERICHIA COLI

Entity 2 Entity 2 polymer

Description description	;5'-D(TPTPTPTPTPTPTPTPTPTPTPTPTPTP TPTPTPTPTPG)-3' ;
Molecular weight formula_weight	6063.9 kDa
Source method src_method	syn
Copy count entity_count	1

Polymer Polymer

Polymer type type	polydeoxyribonucleotide
Chain IDs strand_id	C

TTTTTTTTTTTTTTTTTTTG

Entity 3 Entity 3 water

Description description	water
Molecular weight formula_weight	18.0 kDa
Source method src_method	nat
Copy count entity_count	128

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6. Fold Classification (SCOP + CATH) 2 domains

CATH v4.4 (2 domains)

Domain ID domain_id	4usgA00
Class class	2 — Mainly Beta
Architecture architecture	30 — Roll
Topology topology	31 — Transcriptional Co-activator pc4; Chain A
Homologous superfamily homologous superfamily	10 — Transcriptional Coactivator Pc4; Chain A

Domain ID domain_id	4usgB00
Class class	2 — Mainly Beta
Architecture architecture	30 — Roll
Topology topology	31 — Transcriptional Co-activator pc4; Chain A
Homologous superfamily homologous superfamily	10 — Transcriptional Coactivator Pc4; Chain A

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Unit-cell length a length_a	67.660 Å
Unit-cell length b length_b	67.660 Å
Unit-cell length c length_c	120.420 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	16

Space group space_group	P 41 21 2
Space-group number int_tables_number	92
Crystal system crystal_system	—

Resolution resolution	1.973 Å
Low-resolution limit resolution_low	47.843 Å
R factor r_factor	0.1879
R_work r_work	0.1853
R_free r_free	0.2120

Crystal structure of PC4 W89Y mutant complex with DNA

1. Protein Identity and Related Structures Protein Identity & Related Structures

ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

4usg__assembly_1__model_1

4usg__assembly_1__model_1 | I(q)

4usg__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer

Polymer Polymer

Entity 3 Entity 3 water

6. Fold Classification (SCOP + CATH) 2 domains

CATH v4.4 (2 domains)

7. Citations (1)

Crystal structure of PC4 W89Y mutant complex with DNA

1. Protein Identity and Related Structures Protein Identity & Related Structures

ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

4usg__assembly_1__model_1

4usg__assembly_1__model_1 | I(q)

4usg__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

Refinement Refinement

Diffraction experiment Diffraction

5. Entities and Polymers Entities & Polymers (3)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

Entity 2 Entity 2 polymer

Polymer Polymer

Entity 3 Entity 3 water

6. Fold Classification (SCOP + CATH) 2 domains

CATH v4.4 (2 domains)

7. Citations (1)