4wrm

Structure of the human CSF-1:CSF-1R complex

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Macrophage colony-stimulating factor 1 receptor

Homo sapiens

UniProt P07333

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Macrophage colony-stimulating factor 1 × 1 (P09603) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CSF1R_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–485; UniProt 20–504

Macrophage colony-stimulating factor 1

Homo sapiens

UniProt P09603

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 Macrophage colony-stimulating factor 1 receptor × 1 (P07333) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CSF1_HUMAN
Isoform P09603-3
PDB entities 2
Chains and sequence ranges Author chain B; PDBConstruct 22–170; UniProt 33–181

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id4wrm
Deposition date deposition_date2014-10-24
Structure title titleStructure of the human CSF-1:CSF-1R complex
Keywords keywordscytokine-cytokine receptor complex; CYTOKINE/CYTOKINE RECEPTOR
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

4wrm__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

4wrm__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

4wrm__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)43.50 Å
Rg (electron density)44.78 Å
Total Rg44.50 Å
Atom count4524
Residues586
Excluded volume80153 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 4wrm__assembly_1__model_1 dimeric (2) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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7. Citations (1)