4ywl

Pyrococcus furiosus MCM N-terminal domain F179A point mutant pentameric ring

Method: X-RAY DIFFRACTION

▼

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Cell division control protein 21

Pyrococcus furiosus

当前结构中的状态

Assembly	物理组成	蛋白状态	分子拷贝数	共同组分	数据核对
1	蛋白同源多聚体	同源多聚体	蛋白 20	ZINC ION × 20 SULFATE ION × 18	与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据

UniProt名称	Q8U3I4_PYRFU
Isoform	—
PDB实体	1
链与序列区间	作者链 A； PDB构建体 3–257； UniProt 2–256 作者链 B； PDB构建体 3–257； UniProt 2–256 作者链 C； PDB构建体 3–257； UniProt 2–256 作者链 D； PDB构建体 3–257； UniProt 2–256 作者链 E； PDB构建体 3–257； UniProt 2–256 作者链 F； PDB构建体 3–257； UniProt 2–256 作者链 G； PDB构建体 3–257； UniProt 2–256 作者链 H； PDB构建体 3–257； UniProt 2–256 作者链 I； PDB构建体 3–257； UniProt 2–256 作者链 J； PDB构建体 3–257； UniProt 2–256

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。

▼

2. 结构基本信息 2. Structure Basics

条目编号 entry_id	4ywl
沉积日期 deposition_date	2015-03-20
结构标题 title	Pyrococcus furiosus MCM N-terminal domain F179A point mutant pentameric ring
关键词 keywords	MCM, helicase, replication, OB-fold, CELL CYCLE; CELL CYCLE
实验方法 method	X-RAY DIFFRACTION

▼

3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

4ywl__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

4ywl__assembly_1__model_1 | I(q)

100 个绘图点；横轴和纵轴均采用对数尺度。

4ywl__assembly_1__model_1 | P(r) · Pending

P(r) 将按相同 assembly/model 分别计算和展示。

Rg（Guinier）	59.57 Å
Rg（电子密度）	58.41 Å
总 Rg	58.47 Å
原子数	40730
残基数	5080
排除体积	727540 Å³
最大 q	0.500 Å⁻¹

Assembly	Model	结构单元	聚集说明	状态	CRYSOL	操作
1	1	`4ywl__assembly_1__model_1`	eicosameric （20）	成功	4.1.3-1-20251215 (887e7ef)	查看下载

▶

4. 晶体学与实验 4. Crystallography & Experiment

▶

5. 实体与聚合物信息 Entities & Polymers (3)

实体 1 Entity 1 polymer

描述 description	Cell division control protein 21
分子量 formula_weight	29324.6 kDa
突变 mutation	F179A
来源方法 src_method	man
拷贝数 entity_count	10

聚合物 Polymer

聚合物类型 type	polypeptide(L)
链编号 strand_id	A,B,C,D,E,F,G,H,I,J
原子数 atom_count	20365

SVDREEMIERFANFLREYTDEDGNPVYRGKITDLLTITPKRSVAIDWMHLNSFDSELAHEVIENPEEGISAAEDAIQIVLREDFQREDVGKIHARFYNLPETLMVKDIGAEHINKLIQVEGIVTRVGEIKPFVSVAVFVCKDCGHEMIVPQKPYESLEKVKKCEQCGSKNIELDVNKSSAVNFQSFRIQDRPETLKGGEMPRFIDGILLDDIVDVALPGDRVIVTGILRVVLEKREKTPIFRKILEVNHIEPVSKEI

来源 Source

来源生物 organism	Pyrococcus furiosus
NCBI 分类编号 ncbi_taxonomy_id	186497
宿主生物 host_organism	Escherichia coli

实体 2 Entity 2 non-polymer

描述 description	ZINC ION
分子量 formula_weight	65.4 kDa
来源方法 src_method	syn
拷贝数 entity_count	10

实体 3 Entity 3 non-polymer

描述 description	SULFATE ION
分子量 formula_weight	96.1 kDa
来源方法 src_method	syn
拷贝数 entity_count	9

▼

6. 折叠分类 (SCOP + CATH) 30 domains

CATH v4.4 (30 domains)

结构域编号 domain_id	4ywlA01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1640 — mini-chromosome maintenance (MCM) complex, chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — mini-chromosome maintenance (MCM) complex, chain A, domain 1

结构域编号 domain_id	4ywlA02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	40 — Beta Barrel
拓扑 Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily	140 — Nucleic acid-binding proteins

结构域编号 domain_id	4ywlA03
类 Class class	2 — Mainly Beta
架构 Architecture architecture	20 — Single Sheet
拓扑 Topology topology	28 — Rubrerythrin, domain 2
同源超家族 H-superfamily homologous superfamily	10 —

结构域编号 domain_id	4ywlB01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1640 — mini-chromosome maintenance (MCM) complex, chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — mini-chromosome maintenance (MCM) complex, chain A, domain 1

结构域编号 domain_id	4ywlB02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	40 — Beta Barrel
拓扑 Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily	140 — Nucleic acid-binding proteins

结构域编号 domain_id	4ywlB03
类 Class class	2 — Mainly Beta
架构 Architecture architecture	20 — Single Sheet
拓扑 Topology topology	28 — Rubrerythrin, domain 2
同源超家族 H-superfamily homologous superfamily	10 —

结构域编号 domain_id	4ywlC01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1640 — mini-chromosome maintenance (MCM) complex, chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — mini-chromosome maintenance (MCM) complex, chain A, domain 1

结构域编号 domain_id	4ywlC02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	40 — Beta Barrel
拓扑 Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily	140 — Nucleic acid-binding proteins

结构域编号 domain_id	4ywlC03
类 Class class	2 — Mainly Beta
架构 Architecture architecture	20 — Single Sheet
拓扑 Topology topology	28 — Rubrerythrin, domain 2
同源超家族 H-superfamily homologous superfamily	10 —

结构域编号 domain_id	4ywlD01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1640 — mini-chromosome maintenance (MCM) complex, chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — mini-chromosome maintenance (MCM) complex, chain A, domain 1

结构域编号 domain_id	4ywlD02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	40 — Beta Barrel
拓扑 Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily	140 — Nucleic acid-binding proteins

结构域编号 domain_id	4ywlD03
类 Class class	2 — Mainly Beta
架构 Architecture architecture	20 — Single Sheet
拓扑 Topology topology	28 — Rubrerythrin, domain 2
同源超家族 H-superfamily homologous superfamily	10 —

结构域编号 domain_id	4ywlE01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1640 — mini-chromosome maintenance (MCM) complex, chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — mini-chromosome maintenance (MCM) complex, chain A, domain 1

结构域编号 domain_id	4ywlE02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	40 — Beta Barrel
拓扑 Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily	140 — Nucleic acid-binding proteins

结构域编号 domain_id	4ywlE03
类 Class class	2 — Mainly Beta
架构 Architecture architecture	20 — Single Sheet
拓扑 Topology topology	28 — Rubrerythrin, domain 2
同源超家族 H-superfamily homologous superfamily	10 —

结构域编号 domain_id	4ywlF01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1640 — mini-chromosome maintenance (MCM) complex, chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — mini-chromosome maintenance (MCM) complex, chain A, domain 1

结构域编号 domain_id	4ywlF02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	40 — Beta Barrel
拓扑 Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily	140 — Nucleic acid-binding proteins

结构域编号 domain_id	4ywlF03
类 Class class	2 — Mainly Beta
架构 Architecture architecture	20 — Single Sheet
拓扑 Topology topology	28 — Rubrerythrin, domain 2
同源超家族 H-superfamily homologous superfamily	10 —

结构域编号 domain_id	4ywlG01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1640 — mini-chromosome maintenance (MCM) complex, chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — mini-chromosome maintenance (MCM) complex, chain A, domain 1

结构域编号 domain_id	4ywlG02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	40 — Beta Barrel
拓扑 Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily	140 — Nucleic acid-binding proteins

结构域编号 domain_id	4ywlG03
类 Class class	2 — Mainly Beta
架构 Architecture architecture	20 — Single Sheet
拓扑 Topology topology	28 — Rubrerythrin, domain 2
同源超家族 H-superfamily homologous superfamily	10 —

结构域编号 domain_id	4ywlH01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1640 — mini-chromosome maintenance (MCM) complex, chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — mini-chromosome maintenance (MCM) complex, chain A, domain 1

结构域编号 domain_id	4ywlH02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	40 — Beta Barrel
拓扑 Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily	140 — Nucleic acid-binding proteins

结构域编号 domain_id	4ywlH03
类 Class class	2 — Mainly Beta
架构 Architecture architecture	20 — Single Sheet
拓扑 Topology topology	28 — Rubrerythrin, domain 2
同源超家族 H-superfamily homologous superfamily	10 —

结构域编号 domain_id	4ywlI01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1640 — mini-chromosome maintenance (MCM) complex, chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — mini-chromosome maintenance (MCM) complex, chain A, domain 1

结构域编号 domain_id	4ywlI02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	40 — Beta Barrel
拓扑 Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily	140 — Nucleic acid-binding proteins

结构域编号 domain_id	4ywlI03
类 Class class	2 — Mainly Beta
架构 Architecture architecture	20 — Single Sheet
拓扑 Topology topology	28 — Rubrerythrin, domain 2
同源超家族 H-superfamily homologous superfamily	10 —

结构域编号 domain_id	4ywlJ01
类 Class class	3 — Alpha Beta
架构 Architecture architecture	30 — 2-Layer Sandwich
拓扑 Topology topology	1640 — mini-chromosome maintenance (MCM) complex, chain A, domain 1
同源超家族 H-superfamily homologous superfamily	10 — mini-chromosome maintenance (MCM) complex, chain A, domain 1

结构域编号 domain_id	4ywlJ02
类 Class class	2 — Mainly Beta
架构 Architecture architecture	40 — Beta Barrel
拓扑 Topology topology	50 — OB fold (Dihydrolipoamide Acetyltransferase, E2P)
同源超家族 H-superfamily homologous superfamily	140 — Nucleic acid-binding proteins

结构域编号 domain_id	4ywlJ03
类 Class class	2 — Mainly Beta
架构 Architecture architecture	20 — Single Sheet
拓扑 Topology topology	28 — Rubrerythrin, domain 2
同源超家族 H-superfamily homologous superfamily	10 —

▶

晶胞边长 a length_a	213.018 Å
晶胞边长 b length_b	213.018 Å
晶胞边长 c length_c	213.978 Å
晶胞夹角 α angle_alpha	90.00 °
晶胞夹角 β angle_beta	90.00 °
晶胞夹角 γ angle_gamma	120.00 °
晶胞分子数 Z z_pdb	60

空间群 space_group	P 32 2 1
空间群编号 int_tables_number	154
晶系 crystal_system	—

分辨率 resolution	3.200 Å
最低分辨率 resolution_low	50.000 Å
R 因子 r_factor	0.2037
R_work r_work	0.2023
R_free r_free	0.2299

Pyrococcus furiosus MCM N-terminal domain F179A point mutant pentameric ring

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Cell division control protein 21

当前结构中的状态

数据库中的同蛋白其他状态

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

4ywl__assembly_1__model_1

4ywl__assembly_1__model_1 | I(q)

4ywl__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (3)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 non-polymer

实体 3 Entity 3 non-polymer

6. 折叠分类 (SCOP + CATH) 30 domains

CATH v4.4 (30 domains)

7. 引用文献 (1)

Pyrococcus furiosus MCM N-terminal domain F179A point mutant pentameric ring

1. 蛋白身份与相关结构 Protein Identity & Related Structures

Cell division control protein 21

当前结构中的状态

数据库中的同蛋白其他状态

单体

同源二聚体

同源四聚体

其他同源多聚体

异源或核酸复合物

2. 结构基本信息 2. Structure Basics

3. Official assembly/model 理论 SAXS Official SAXS Profiles

4ywl__assembly_1__model_1

4ywl__assembly_1__model_1 | I(q)

4ywl__assembly_1__model_1 | P(r) · Pending

4. 晶体学与实验 4. Crystallography & Experiment

晶胞参数 Unit Cell

对称性 Symmetry

精修参数 Refinement

衍射实验 Diffraction

5. 实体与聚合物信息 Entities & Polymers (3)

实体 1 Entity 1 polymer

聚合物 Polymer

来源 Source

实体 2 Entity 2 non-polymer

实体 3 Entity 3 non-polymer

6. 折叠分类 (SCOP + CATH) 30 domains

CATH v4.4 (30 domains)

7. 引用文献 (1)