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5a5h

The crystal structure of the GST-like domains complex of EPRS C92SC105SC123S mutant-AIMP2

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

BIFUNCTIONAL GLUTAMATE/PROLINE--TRNA LIGASE

HOMO SAPIENS

UniProt P07814

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONA L PROTEIN 2 × 1 （Q13155） water × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONA L PROTEIN 2 × 1 （Q13155） water × 2 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 2 AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONA L PROTEIN 2 × 1 （Q13155） water × 2 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 2 AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONA L PROTEIN 2 × 1 （Q13155） water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1fyj 7bbu

2 assemblies

Homodimer
4hvc 4k86 4k87 4k88 5v58 5vad 7bbu 7f98 7f99 7f9a 7f9b 7f9c

26 assemblies; showing the first 12

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
5a1n 5a34 5a34 5a34 5a34 5a5h 5a5h 5a5h 5a5h 5bmu 5bmu 5bmu

16 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name SYEP_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–175； UniProt 1–175 Author chain C； PDBConstruct 1–175； UniProt 1–175 Author chain E； PDBConstruct 1–175； UniProt 1–175 Author chain G； PDBConstruct 1–175； UniProt 1–175

AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONA L PROTEIN 2

HOMO SAPIENS

UniProt Q13155

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 BIFUNCTIONAL GLUTAMATE/PROLINE--TRNA LIGASE × 1 （P07814） water × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 BIFUNCTIONAL GLUTAMATE/PROLINE--TRNA LIGASE × 1 （P07814） water × 2 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 2 BIFUNCTIONAL GLUTAMATE/PROLINE--TRNA LIGASE × 1 （P07814） water × 2 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 2 BIFUNCTIONAL GLUTAMATE/PROLINE--TRNA LIGASE × 1 （P07814） water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
4dpg 4dpg 4dpg 4dpg 4ycu 4ycw 4ycw 5a1n 5a34 5a34 5a34 5a34

24 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name AIMP2_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 2–232； UniProt 90–320 Author chain D； PDBConstruct 2–232； UniProt 90–320 Author chain F； PDBConstruct 2–232； UniProt 90–320 Author chain H； PDBConstruct 2–232； UniProt 90–320

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id5a5h
Deposition date deposition_date2015-06-18
Structure title titleThe crystal structure of the GST-like domains complex of EPRS C92SC105SC123S mutant-AIMP2
Keywords keywordsTRANSLATION, EPRS, AIMP2, GST-LIKE DOMAIN; TRANSLATION
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5a5h__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5a5h__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

5a5h__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）22.33 Å
Rg (electron density)21.07 Å
Total Rg21.98 Å
Atom count2890
Residues377
Excluded volume51580 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 5a5h__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 5a5h__assembly_2__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 5a5h__assembly_3__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 5a5h__assembly_4__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 8 domains

CATH v4.4 (8 domains)

Domain ID domain_id5a5hA00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
Homologous superfamily homologous superfamily130 —
Domain ID domain_id5a5hB00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
Homologous superfamily homologous superfamily130 —
Domain ID domain_id5a5hC00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
Homologous superfamily homologous superfamily130 —
Domain ID domain_id5a5hD00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
Homologous superfamily homologous superfamily130 —
Domain ID domain_id5a5hE00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
Homologous superfamily homologous superfamily130 —
Domain ID domain_id5a5hF00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
Homologous superfamily homologous superfamily130 —
Domain ID domain_id5a5hG00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
Homologous superfamily homologous superfamily130 —
Domain ID domain_id5a5hH00
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology1050 — Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2
Homologous superfamily homologous superfamily130 —
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7. Citations (1)