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5cui

Crystal structure of Human Defensin-5 R28A mutant.

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Defensin-5

OrganismNot specified

UniProt Q01523

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 2 CHLORIDE ION × 3 2-(2-METHOXYETHOXY)ETHANOL × 1 PENTAETHYLENE GLYCOL × 1 water × 2 Consistent with protein count
2 Protein homooligomer Homooligomer Protein 4 CHLORIDE ION × 8 2-(2-METHOXYETHOXY)ETHANOL × 3 (4S)-2-METHYL-2,4-PENTANEDIOL × 3 water × 4 Consistent with protein count
3 Protein homooligomer Homooligomer Protein 6 CHLORIDE ION × 11 2-(2-METHOXYETHOXY)ETHANOL × 4 PENTAETHYLENE GLYCOL × 1 (4S)-2-METHYL-2,4-PENTANEDIOL × 3 water × 6 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1zmp 1zmp 1zmp 1zmp 2lxz 4e82 4e82 4e83 4e83 4e86 4e86 4e86

19 assemblies; showing the first 12

Homodimer
2mit 3i5w 4e83 4e86 4e86 4e86 4e86 4e86 4rbw 4rbw 5cui

11 assemblies

Homotetramer
5cui

1 assemblies

Other homooligomers
1zmp 1zmp 1zmp 5cui 5cuj 5cum

6 assemblies

Heteromeric or nucleic-acid complex

None

View Construct and Data Evidence
UniProt name DEF5_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–32； UniProt 63–94 Author chain B； PDBConstruct 1–32； UniProt 63–94 Author chain C； PDBConstruct 1–32； UniProt 63–94 Author chain D； PDBConstruct 1–32； UniProt 63–94 Author chain E； PDBConstruct 1–32； UniProt 63–94 Author chain F； PDBConstruct 1–32； UniProt 63–94

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id5cui
Deposition date deposition_date2015-07-24
Structure title titleCrystal structure of Human Defensin-5 R28A mutant.
Keywords keywordsPANETH CELLS DEFENSIN, HUMAN ALPHA-DEFENSIN, INTESTINAL DEFENSIN, ANTIMICROBIAL PROTEIN; ANTIMICROBIAL PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5cui__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5cui__assembly_1__model_1 | I(q)

10-2 10-1 104 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

5cui__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）12.81 Å
Rg (electron density)11.59 Å
Total Rg12.82 Å
Atom count505
Residues64
Excluded volume8972 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 5cui__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 5cui__assembly_2__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 5cui__assembly_3__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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7. Citations (1)