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5git

BTB domain of KEAP1 in complex with XX3

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Kelch-like ECH-associated protein 1

Homo sapiens

UniProt Q14145

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein monomer Monomer Protein 1 ;[(3aS,5R,5aS,6S,8S,8aS,9S,9aR)-9-acetyloxy-8-hydroxy-5,8a-dimethyl-1-methylidene-2-oxo-4,5,5a,6,7,8,9,9a-octahydro-3aH-azuleno[6,5-b]furan-6-yl] acetate ; × 1 water × 1 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1u6d 1zgk 3vng 3vnh 3zgc 4cxi 4ifj 4ifn 4in4 4in4 4in4 4iqk

105 assemblies; showing the first 12

Homodimer
3zgd 4cxj 4cxt 4l7b 5dad 5daf 6ffm 6rog 6w67 6w68 6w69 7exi

35 assemblies; showing the first 12

Homotetramer

None

Other homooligomers
4l7c 4l7d 4n1b

3 assemblies

Heteromeric or nucleic-acid complex
3zgc 4ifl 4ifl 5f72 5f72 5nlb 5wfv 5wg1 5x54 5x54 6fmp 6fmq

52 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name KEAP1_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 5–137； UniProt 48–180

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id5git
Deposition date deposition_date2016-06-25
Structure title titleBTB domain of KEAP1 in complex with XX3
Keywords keywordsSIGNALING PROTEIN, TRANSCRIPTION; TRANSCRIPTION
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5git__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5git__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

5git__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）17.46 Å
Rg (electron density)16.56 Å
Total Rg17.45 Å
Atom count1040
Residues130
Excluded volume18713 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 5git__assembly_1__model_1 monomeric （1） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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6. Fold Classification (SCOP + CATH) 2 domains

SCOP 2.08 (1 domains)

Domain ID domain_idd5gita_
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.42 — POZ domain
Superfamily Superfamily superfamilyd.42.1 — POZ domain
Family Family familyd.42.1.0 — automated matches

CATH v4.4 (1 domains)

Domain ID domain_id5gitA01
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology710 — Potassium Channel Kv1.1; Chain A
Homologous superfamily homologous superfamily10 — Potassium Channel Kv1.1; Chain A
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7. Citations (1)