Endonuclease 8-like 1
Homo sapiens
当前结构中的状态
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白单体 | 单体 | 蛋白 1 | water × 1 | 与蛋白数一致 |
数据库中的同蛋白其他状态
查看构建体与数据证据
| UniProt名称 | NEIL1_HUMAN |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 1–290； UniProt 1–290 |
5itq
Crystal Structure of Human NEIL1, Free Protein
1. 蛋白身份与相关结构 Protein Identity & Related Structures
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
2. 结构基本信息 2. Structure Basics
| 条目编号 entry_id | 5itq |
| 沉积日期 deposition_date | 2016-03-17 |
| 结构标题 title | Crystal Structure of Human NEIL1, Free Protein |
| 关键词 keywords | DNA glycosylase NEIL1 Fpg Nei base excision repair, DNA BINDING PROTEIN-DNA complex; DNA BINDING PROTEIN/DNA |
| 实验方法 method | X-RAY DIFFRACTION |
3. Official assembly/model 理论 SAXS Official SAXS Profiles
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
5itq__assembly_1__model_1
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
5itq__assembly_1__model_1 | I(q)
5itq__assembly_1__model_1 | P(r) · Pending
| Rg（Guinier） | 22.06 Å |
| Rg（电子密度） | 21.20 Å |
| 总 Rg | 22.12 Å |
| 原子数 | 2265 |
| 残基数 | 286 |
| 排除体积 | 40203 ų |
| 最大 q | 0.500 Å⁻¹ |
4. 晶体学与实验 4. Crystallography & Experiment
5. 实体与聚合物信息 Entities & Polymers (2)
6. 折叠分类 (SCOP + CATH) 5 domains
SCOP 2.08 (3 domains)
| 结构域编号 domain_id | d5itqa1 |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.113 — N-terminal domain of MutM-like DNA repair proteins |
| 超家族 Superfamily superfamily | b.113.1 — N-terminal domain of MutM-like DNA repair proteins |
| 家族 Family family | b.113.1.1 — N-terminal domain of MutM-like DNA repair proteins |
| 结构域编号 domain_id | d5itqa2 |
| 类 Class class | a — All alpha proteins |
| 折叠类型 Fold fold | a.156 — S13-like H2TH domain |
| 超家族 Superfamily superfamily | a.156.1 — S13-like H2TH domain |
| 家族 Family family | a.156.1.0 — automated matches |
| 结构域编号 domain_id | d5itqa3 |
| 类 Class class | g — Small proteins |
| 折叠类型 Fold fold | g.39 — Glucocorticoid receptor-like (DNA-binding domain) |
| 超家族 Superfamily superfamily | g.39.1 — Glucocorticoid receptor-like (DNA-binding domain) |
| 家族 Family family | g.39.1.0 — automated matches |
CATH v4.4 (2 domains)
| 结构域编号 domain_id | 5itqA01 |
| 类 Class class | 3 — Alpha Beta |
| 架构 Architecture architecture | 20 — Alpha-Beta Barrel |
| 拓扑 Topology topology | 190 — N-terminal domain of MutM-like DNA repair proteins |
| 同源超家族 H-superfamily homologous superfamily | 10 — MutM-like, N-terminal |
| 结构域编号 domain_id | 5itqA02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 8 — Helicase, Ruva Protein; domain 3 |
| 同源超家族 H-superfamily homologous superfamily | 50 — |