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5km2

Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) CMP catalytic product complex

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Histidine triad nucleotide-binding protein 1

Homo sapiens

UniProt P49773

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 2 CYTIDINE-5'-MONOPHOSPHATE × 1 GLYCEROL × 1 CHLORIDE ION × 1 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer
1av5 1kpa 1kpb 1kpc 1kpc 1kpe 1kpf 3tw2 4eqe 4eqg 4eqh 4zkl

68 assemblies; showing the first 12

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex

None

View Construct and Data Evidence
UniProt name HINT1_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 4–129； UniProt 1–126 Author chain B； PDBConstruct 4–129； UniProt 1–126

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id5km2
Deposition date deposition_date2016-06-26
Structure title titleHuman Histidine Triad Nucleotide Binding Protein 1 (hHint1) CMP catalytic product complex
Keywords keywordsHINT, histidine triad, HIT, HYDROLASE; HYDROLASE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5km2__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5km2__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

5km2__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）17.64 Å
Rg (electron density)16.65 Å
Total Rg17.63 Å
Atom count1790
Residues227
Excluded volume31809 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 5km2__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

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6. Fold Classification (SCOP + CATH) 4 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd5km2a_
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.13 — HIT-like
Superfamily Superfamily superfamilyd.13.1 — HIT-like
Family Family familyd.13.1.1 — HIT (HINT, histidine triad) family of protein kinase-interacting proteins
Domain ID domain_idd5km2b_
Class classd — Alpha and beta proteins (a+b)
Fold Fold foldd.13 — HIT-like
Superfamily Superfamily superfamilyd.13.1 — HIT-like
Family Family familyd.13.1.1 — HIT (HINT, histidine triad) family of protein kinase-interacting proteins

CATH v4.4 (2 domains)

Domain ID domain_id5km2A00
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology428 — HIT family, subunit A
Homologous superfamily homologous superfamily10 — HIT-like
Domain ID domain_id5km2B00
Class class3 — Alpha Beta
Architecture architecture30 — 2-Layer Sandwich
Topology topology428 — HIT family, subunit A
Homologous superfamily homologous superfamily10 — HIT-like
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7. Citations (1)