5l4k

The human 26S proteasome lid

Method: ELECTRON MICROSCOPY
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1. 蛋白身份与相关结构 Protein Identity & Related Structures

26S proteasome non-ATPase regulatory subunit 4

物种未注明

UniProt P55036

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 12 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSMD4_HUMAN
Isoform —
PDB实体 1
链与序列区间 作者链 W; PDB构建体 1–377; UniProt 1–377

26S proteasome non-ATPase regulatory subunit 14

物种未注明

UniProt O00487

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 12 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSDE_HUMAN
Isoform —
PDB实体 2
链与序列区间 作者链 V; PDB构建体 1–310; UniProt 1–310

26S proteasome non-ATPase regulatory subunit 8

物种未注明

UniProt P48556

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 12 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSMD8_HUMAN
Isoform —
PDB实体 3
链与序列区间 作者链 T; PDB构建体 1–350; UniProt 1–350

26S proteasome complex subunit DSS1

物种未注明

UniProt P60896

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 12 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 DSS1_HUMAN
Isoform —
PDB实体 4
链与序列区间 作者链 Y; PDB构建体 1–70; UniProt 1–70

26S proteasome non-ATPase regulatory subunit 2

物种未注明

UniProt Q13200

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 12 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSMD2_HUMAN
Isoform —
PDB实体 5
链与序列区间 作者链 Z; PDB构建体 1–908; UniProt 1–908

26S proteasome non-ATPase regulatory subunit 1

物种未注明

UniProt Q99460

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 12 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSMD1_HUMAN
Isoform —
PDB实体 6
链与序列区间 作者链 N; PDB构建体 1–953; UniProt 1–953

26S proteasome non-ATPase regulatory subunit 3

物种未注明

UniProt O43242

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 12 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSMD3_HUMAN
Isoform —
PDB实体 7
链与序列区间 作者链 S; PDB构建体 1–534; UniProt 1–534

26S proteasome non-ATPase regulatory subunit 12

物种未注明

UniProt O00232

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 12 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSD12_HUMAN
Isoform —
PDB实体 8
链与序列区间 作者链 P; PDB构建体 1–456; UniProt 1–456

26S proteasome non-ATPase regulatory subunit 11

物种未注明

UniProt O00231

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 12 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSD11_HUMAN
Isoform —
PDB实体 9
链与序列区间 作者链 Q; PDB构建体 1–422; UniProt 1–422

26S proteasome non-ATPase regulatory subunit 6

物种未注明

UniProt Q15008

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 12 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSMD6_HUMAN
Isoform —
PDB实体 10
链与序列区间 作者链 R; PDB构建体 1–389; UniProt 1–389

26S proteasome non-ATPase regulatory subunit 7

物种未注明

UniProt P51665

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 12 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 13 × 1 (Q9UNM6) 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSMD7_HUMAN
Isoform —
PDB实体 11
链与序列区间 作者链 U; PDB构建体 1–324; UniProt 1–324

26S proteasome non-ATPase regulatory subunit 13

物种未注明

UniProt Q9UNM6

当前结构中的状态

Assembly 物理组成 蛋白状态 分子拷贝数 共同组分 数据核对
1 蛋白异源复合物 异源复合物 蛋白 12 26S proteasome non-ATPase regulatory subunit 4 × 1 (P55036) 26S proteasome non-ATPase regulatory subunit 14 × 1 (O00487) 26S proteasome non-ATPase regulatory subunit 8 × 1 (P48556) 26S proteasome complex subunit DSS1 × 1 (P60896) 26S proteasome non-ATPase regulatory subunit 2 × 1 (Q13200) 26S proteasome non-ATPase regulatory subunit 1 × 1 (Q99460) 26S proteasome non-ATPase regulatory subunit 3 × 1 (O43242) 26S proteasome non-ATPase regulatory subunit 12 × 1 (O00232) 26S proteasome non-ATPase regulatory subunit 11 × 1 (O00231) 26S proteasome non-ATPase regulatory subunit 6 × 1 (Q15008) 26S proteasome non-ATPase regulatory subunit 7 × 1 (P51665) 与蛋白数一致

数据库中的同蛋白其他状态

查看构建体与数据证据
UniProt名称 PSD13_HUMAN
Isoform —
PDB实体 12
链与序列区间 作者链 O; PDB构建体 1–376; UniProt 1–376

页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中;数据库内部编号、导入时间和 assembly 操作表达式仅用于维护,因此不在读者页面展示。

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2. 结构基本信息 2. Structure Basics

条目编号 entry_id5l4k
沉积日期 deposition_date2016-05-25
结构标题 titleThe human 26S proteasome lid
关键词 keywordsproteostasis, AAA-ATPase, structural protein; STRUCTURAL PROTEIN
实验方法 methodELECTRON MICROSCOPY
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3. Official assembly/model 理论 SAXS Official SAXS Profiles

页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。

5l4k__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

下载该曲线 .dat

5l4k__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 个绘图点;横轴和纵轴均采用对数尺度。

5l4k__assembly_1__model_1 | P(r) · Pending

新版 assembly/model P(r) 尚未计算 此处仅保留位置,不展示旧数据 r (Angstrom) P(r)
P(r) 将按相同 assembly/model 分别计算和展示。
Rg(Guinier)73.15 Å
Rg(电子密度)72.91 Å
总 Rg72.97 Å
原子数79649
残基数5000
排除体积709600 ų
最大 q0.500 Å⁻¹
Assembly Model 结构单元 聚集说明 状态 CRYSOL 操作
1 1 5l4k__assembly_1__model_1 dodecameric (12) 成功 4.1.3-1-20251215 (887e7ef) 查看 下载
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4. 晶体学与实验 4. Crystallography & Experiment

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5. 实体与聚合物信息 Entities & Polymers (12)

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6. 折叠分类 (SCOP + CATH) 1 domains

SCOP 2.08 (1 domains)

结构域编号 domain_idd5l4kw_
类 Class classc — Alpha and beta proteins (a/b)
折叠类型 Fold foldc.62 — vWA-like
超家族 Superfamily superfamilyc.62.1 — vWA-like
家族 Family familyc.62.1.1 — Integrin A (or I) domain
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7. 引用文献 (1)