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5osh

Structure of retromer VPS29-VPS35C subunits complexed with RidL N-terminal domain (1-236)

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Vacuolar protein sorting-associated protein 29

Homo sapiens

UniProt Q9UBQ0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 Vacuolar protein sorting-associated protein 35 × 1 （Q96QK1） Interaptin × 1 （G8UZ99） Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 Vacuolar protein sorting-associated protein 35 × 1 （Q96QK1） Interaptin × 1 （G8UZ99） Consistent with protein count
3 Protein heterocomplex Heteromer Protein 3 Vacuolar protein sorting-associated protein 35 × 1 （Q96QK1） Interaptin × 1 （G8UZ99） Consistent with protein count
4 Protein heterocomplex Heteromer Protein 3 Vacuolar protein sorting-associated protein 35 × 1 （Q96QK1） Interaptin × 1 （G8UZ99） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1w24

1 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2r17 2r17 5gtu 5osh 5osh 5osh 5osh 5osi 5osi 5osi 5osi 5wyh

34 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name VPS29_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–182； UniProt 1–182 Author chain D； PDBConstruct 1–182； UniProt 1–182 Author chain G； PDBConstruct 1–182； UniProt 1–182 Author chain J； PDBConstruct 1–182； UniProt 1–182

Vacuolar protein sorting-associated protein 35

Homo sapiens

UniProt Q96QK1

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 Vacuolar protein sorting-associated protein 29 × 1 （Q9UBQ0） Interaptin × 1 （G8UZ99） Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 Vacuolar protein sorting-associated protein 29 × 1 （Q9UBQ0） Interaptin × 1 （G8UZ99） Consistent with protein count
3 Protein heterocomplex Heteromer Protein 3 Vacuolar protein sorting-associated protein 29 × 1 （Q9UBQ0） Interaptin × 1 （G8UZ99） Consistent with protein count
4 Protein heterocomplex Heteromer Protein 3 Vacuolar protein sorting-associated protein 29 × 1 （Q9UBQ0） Interaptin × 1 （G8UZ99） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
5f0k 5f0k 5f0k 5f0k 5f0k

5 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2r17 2r17 5f0j 5f0l 5f0m 5f0p 5osh 5osh 5osh 5osh 5osi 5osi

24 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name VPS35_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–299； UniProt 482–780 Author chain E； PDBConstruct 1–299； UniProt 482–780 Author chain H； PDBConstruct 1–299； UniProt 482–780 Author chain K； PDBConstruct 1–299； UniProt 482–780

Interaptin

Legionella pneumophila subsp. pneumophila ATCC 43290

UniProt G8UZ99

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 3 Vacuolar protein sorting-associated protein 29 × 1 （Q9UBQ0） Vacuolar protein sorting-associated protein 35 × 1 （Q96QK1） Consistent with protein count
2 Protein heterocomplex Heteromer Protein 3 Vacuolar protein sorting-associated protein 29 × 1 （Q9UBQ0） Vacuolar protein sorting-associated protein 35 × 1 （Q96QK1） Consistent with protein count
3 Protein heterocomplex Heteromer Protein 3 Vacuolar protein sorting-associated protein 29 × 1 （Q9UBQ0） Vacuolar protein sorting-associated protein 35 × 1 （Q96QK1） Consistent with protein count
4 Protein heterocomplex Heteromer Protein 3 Vacuolar protein sorting-associated protein 29 × 1 （Q9UBQ0） Vacuolar protein sorting-associated protein 35 × 1 （Q96QK1） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
5oh5 5oh6 5oh6 5ot4 5ot4 5ot4 5ot4

7 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
5osh 5osh 5osh 5osh 5osi 5osi 5osi 5wyh 5wyh

9 assemblies

View Construct and Data Evidence
UniProt name G8UZ99_LEGPN
Isoform —
PDB entities 3
Chains and sequence ranges Author chain C； PDBConstruct 3–223； UniProt 3–223 Author chain F； PDBConstruct 3–223； UniProt 3–223 Author chain I； PDBConstruct 3–223； UniProt 3–223 Author chain L； PDBConstruct 3–223； UniProt 3–223

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id5osh
Deposition date deposition_date2017-08-17
Structure title titleStructure of retromer VPS29-VPS35C subunits complexed with RidL N-terminal domain (1-236)
Keywords keywordsRetromer, Legionella pneumophila, TRANSPORT PROTEIN; TRANSPORT PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5osh__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5osh__assembly_1__model_1 | I(q)

10-2 10-1 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

5osh__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）34.27 Å
Rg (electron density)33.79 Å
Total Rg34.21 Å
Atom count5621
Residues698
Excluded volume100180 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 5osh__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 5osh__assembly_2__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
3 1 5osh__assembly_3__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
4 1 5osh__assembly_4__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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7. Citations (1)