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5xou

Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 7T8 on the guide strand

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

TtAgo (D546N)

Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)

UniProt Q746M7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Homooligomer Protein 2 DNA 4 ;DNA (5'-D(P*TP*GP*AP*GP*GP*TP*AP*TP*GP*GP*TP*TP*GP*T)-3') ; × 2 ;DNA (5'-D(*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3') ; × 2 MAGNESIUM ION × 2 water × 4 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3dlb 3dlh 3dlh 3f73 3f73 3hjf 3hk2 3hk2 3hm9 3ho1 3hvr 3hvr

31 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name Q746M7_THET2
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–685； UniProt 1–685 Author chain B； PDBConstruct 1–685； UniProt 1–685

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id5xou
Deposition date deposition_date2017-05-31
Structure title titleCrystal structure of T. thermophilus Argonaute protein complexed with a bulge 7T8 on the guide strand
Keywords keywordsArgonaute, Bulge, miRNA, mismatch, DNA BINDING PROTEIN; DNA BINDING PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

5xou__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

5xou__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

5xou__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）35.27 Å
Rg (electron density)35.06 Å
Total Rg35.48 Å
Atom count10077
Residues1200
Excluded volume175710 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 5xou__assembly_1__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

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7. Citations (1)