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6lnt

Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Envelope protein

OrganismNot specified

UniProt A0A024B7W1

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 720 Fab DV62.5 heavy-chain variable region × 120 Fab DV62.5 light-chain variable region × 120 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 12 Fab DV62.5 heavy-chain variable region × 2 Fab DV62.5 light-chain variable region × 2 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 60 Fab DV62.5 heavy-chain variable region × 10 Fab DV62.5 light-chain variable region × 10 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 72 Fab DV62.5 heavy-chain variable region × 12 Fab DV62.5 light-chain variable region × 12 Consistent with protein count
5 Protein heterocomplex Heteromer Protein 12 Fab DV62.5 heavy-chain variable region × 2 Fab DV62.5 light-chain variable region × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
5jmt 6ld1 6ld2 6ld3 6ld4 6ld5

6 assemblies

Homodimer
5iy3

1 assemblies

Homotetramer

None

Other homooligomers
6lnu 6lnu 6lnu 6lnu 6lnu

5 assemblies

Heteromeric or nucleic-acid complex
5gzr 5gzr 5gzr 5gzr 5gzr 5gzr 5h30 5h30 5h30 5h30 5h30 5h30

94 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name POLG_ZIKVF
Isoform —
PDB entities 1, 2, 5
Chains and sequence ranges Author chain A； PDBConstruct 1–504； UniProt 291–794 Author chain B； PDBConstruct 1–504； UniProt 291–794 Author chain C； PDBConstruct 1–504； UniProt 291–794 Author chain D； PDBConstruct 1–163； UniProt 128–290 Author chain E； PDBConstruct 1–163； UniProt 128–290 Author chain F； PDBConstruct 1–163； UniProt 128–290 Author chain M； PDBConstruct 1–117； UniProt 6–122 Author chain N； PDBConstruct 1–117； UniProt 6–122

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6lnt
Deposition date deposition_date2020-01-02
Structure title titleCryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab
Keywords keywordsimmature Zika virus, human antibody, virus; VIRUS
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6lnt__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6lnt__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 1011 1012 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6lnt__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）0.00 Å
Rg (electron density)222.40 Å
Total Rg222.50 Å
Atom count0
Residues0
Excluded volume21185000 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6lnt__assembly_1__model_1 720-meric （720） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 6lnt__assembly_2__model_1 dodecameric （12） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
3 1 6lnt__assembly_3__model_1 60-meric （60） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
4 1 6lnt__assembly_4__model_1 72-meric （72） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
5 1 6lnt__assembly_5__model_1 dodecameric （12） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

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7. Citations (1)