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6n8c

Structure of the Huntingtin tetramer/dimer mixture determined by paramagnetic NMR

Method: SOLUTION NMR
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Huntingtin

Homo sapiens

UniProt P42858

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 4 No other associated polymer Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2ld0 2ld2 6rmh 6yej

4 assemblies

Homodimer

None

Homotetramer
6n8c

1 assemblies

Other homooligomers

None

Heteromeric or nucleic-acid complex
3io4 3io6 3ior 3iot 3iou 3iov 3iow 3lrh 3lrh 3lrh 3lrh 3lrh

34 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name HD_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–23； UniProt 2–24 Author chain B； PDBConstruct 1–23； UniProt 2–24 Author chain C； PDBConstruct 1–23； UniProt 2–24 Author chain D； PDBConstruct 1–23； UniProt 2–24

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6n8c
Deposition date deposition_date2018-11-29
Structure title titleStructure of the Huntingtin tetramer/dimer mixture determined by paramagnetic NMR
Keywords keywordstetramer, dimer of dimers, UNKNOWN FUNCTION; UNKNOWN FUNCTION
Experimental Method methodSOLUTION NMR
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6n8c__assembly_1__model_5

Assembly 1 · Model 5 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6n8c__assembly_1__model_5 | I(q)

10-2 10-1 104 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6n8c__assembly_1__model_5 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）13.37 Å
Rg (electron density)11.75 Å
Total Rg13.31 Å
Atom count1140
Residues68
Excluded volume10150 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6n8c__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 2 6n8c__assembly_1__model_2 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 3 6n8c__assembly_1__model_3 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 4 6n8c__assembly_1__model_4 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 5 6n8c__assembly_1__model_5 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 6 6n8c__assembly_1__model_6 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 7 6n8c__assembly_1__model_7 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 8 6n8c__assembly_1__model_8 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 9 6n8c__assembly_1__model_9 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 10 6n8c__assembly_1__model_10 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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7. Citations (1)