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6nk7

Electron Cryo-Microscopy of Chikungunya in Complex with Mouse Mxra8 Receptor

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

E1 glycoprotein

Chikungunya virus

UniProt Q88628

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 1020 E3 glycoprotein × 240 （D2KBQ2） Matrix remodeling-associated protein 8 × 60 （Q9DBV4） 2-acetamido-2-deoxy-beta-D-glucopyranose × 300 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 17 E3 glycoprotein × 4 （D2KBQ2） Matrix remodeling-associated protein 8 × 1 （Q9DBV4） 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 85 E3 glycoprotein × 20 （D2KBQ2） Matrix remodeling-associated protein 8 × 5 （Q9DBV4） 2-acetamido-2-deoxy-beta-D-glucopyranose × 25 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 102 E3 glycoprotein × 24 （D2KBQ2） Matrix remodeling-associated protein 8 × 6 （Q9DBV4） 2-acetamido-2-deoxy-beta-D-glucopyranose × 30 Consistent with protein count
5 Protein heterocomplex Heteromer Protein 17 E3 glycoprotein × 4 （D2KBQ2） Matrix remodeling-associated protein 8 × 1 （Q9DBV4） 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers
8fcg

1 assemblies

Heteromeric or nucleic-acid complex
6nk7 6nk7 6nk7 6nk7 6nk7 6w09 6w09 6w09 6w09 6w09 9bbn 9bhh

13 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name Q88628_CHIKV
Isoform —
PDB entities 1, 2, 3
Chains and sequence ranges Author chain A； PDBConstruct 1–439； UniProt 810–1248 Author chain B； PDBConstruct 1–439； UniProt 810–1248 Author chain C； PDBConstruct 1–439； UniProt 810–1248 Author chain D； PDBConstruct 1–439； UniProt 810–1248 Author chain E； PDBConstruct 1–419； UniProt 330–748 Author chain F； PDBConstruct 1–419； UniProt 330–748 Author chain G； PDBConstruct 1–419； UniProt 330–748 Author chain H； PDBConstruct 1–419； UniProt 330–748 Author chain I； PDBConstruct 1–151； UniProt 111–261 Author chain J； PDBConstruct 1–151； UniProt 111–261 Author chain K； PDBConstruct 1–151； UniProt 111–261 Author chain L； PDBConstruct 1–151； UniProt 111–261

E3 glycoprotein

Chikungunya virus

UniProt D2KBQ2

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 1020 E1 glycoprotein × 240 （Q88628） E2 glycoprotein × 240 （Q88628） Capsid protein × 240 （Q88628） Matrix remodeling-associated protein 8 × 60 （Q9DBV4） 2-acetamido-2-deoxy-beta-D-glucopyranose × 300 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 17 E1 glycoprotein × 4 （Q88628） E2 glycoprotein × 4 （Q88628） Capsid protein × 4 （Q88628） Matrix remodeling-associated protein 8 × 1 （Q9DBV4） 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 85 E1 glycoprotein × 20 （Q88628） E2 glycoprotein × 20 （Q88628） Capsid protein × 20 （Q88628） Matrix remodeling-associated protein 8 × 5 （Q9DBV4） 2-acetamido-2-deoxy-beta-D-glucopyranose × 25 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 102 E1 glycoprotein × 24 （Q88628） E2 glycoprotein × 24 （Q88628） Capsid protein × 24 （Q88628） Matrix remodeling-associated protein 8 × 6 （Q9DBV4） 2-acetamido-2-deoxy-beta-D-glucopyranose × 30 Consistent with protein count
5 Protein heterocomplex Heteromer Protein 17 E1 glycoprotein × 4 （Q88628） E2 glycoprotein × 4 （Q88628） Capsid protein × 4 （Q88628） Matrix remodeling-associated protein 8 × 1 （Q9DBV4） 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6nk7 6nk7 6nk7 6nk7 6nk7 9bbn 9bhh

7 assemblies

View Construct and Data Evidence
UniProt name D2KBQ2_CHIKV
Isoform —
PDB entities 4
Chains and sequence ranges Author chain U； PDBConstruct 1–60； UniProt 266–325 Author chain V； PDBConstruct 1–60； UniProt 266–325 Author chain W； PDBConstruct 1–60； UniProt 266–325 Author chain X； PDBConstruct 1–60； UniProt 266–325

Matrix remodeling-associated protein 8

Mus musculus

UniProt Q9DBV4

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 1020 E1 glycoprotein × 240 （Q88628） E2 glycoprotein × 240 （Q88628） Capsid protein × 240 （Q88628） E3 glycoprotein × 240 （D2KBQ2） 2-acetamido-2-deoxy-beta-D-glucopyranose × 300 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 17 E1 glycoprotein × 4 （Q88628） E2 glycoprotein × 4 （Q88628） Capsid protein × 4 （Q88628） E3 glycoprotein × 4 （D2KBQ2） 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 85 E1 glycoprotein × 20 （Q88628） E2 glycoprotein × 20 （Q88628） Capsid protein × 20 （Q88628） E3 glycoprotein × 20 （D2KBQ2） 2-acetamido-2-deoxy-beta-D-glucopyranose × 25 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 102 E1 glycoprotein × 24 （Q88628） E2 glycoprotein × 24 （Q88628） Capsid protein × 24 （Q88628） E3 glycoprotein × 24 （D2KBQ2） 2-acetamido-2-deoxy-beta-D-glucopyranose × 30 Consistent with protein count
5 Protein heterocomplex Heteromer Protein 17 E1 glycoprotein × 4 （Q88628） E2 glycoprotein × 4 （Q88628） Capsid protein × 4 （Q88628） E3 glycoprotein × 4 （D2KBQ2） 2-acetamido-2-deoxy-beta-D-glucopyranose × 5 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
6jo7 6jo7

2 assemblies

Homodimer
6nk3

1 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
6nk6 6nk6 6nk6 6nk6 6nk6 6nk7 6nk7 6nk7 6nk7 6nk7

10 assemblies

View Construct and Data Evidence
UniProt name MXRA8_MOUSE
Isoform —
PDB entities 5
Chains and sequence ranges Author chain N； PDBConstruct 1–261； UniProt 32–292

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6nk7
Deposition date deposition_date2019-01-04
Structure title titleElectron Cryo-Microscopy of Chikungunya in Complex with Mouse Mxra8 Receptor
Keywords keywordsChikungunya, viral receptor, Mxra8, Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID, VIRUS; VIRUS
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6nk7__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6nk7__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 1011 1012 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6nk7__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）0.00 Å
Rg (electron density)275.60 Å
Total Rg275.70 Å
Atom count2112300
Residues272220
Excluded volume37437000 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6nk7__assembly_1__model_1 1020-meric （1020） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 6nk7__assembly_2__model_1 heptadecameric （17） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
3 1 6nk7__assembly_3__model_1 85-meric （85） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
4 1 6nk7__assembly_4__model_1 102-meric （102） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
5 1 6nk7__assembly_5__model_1 heptadecameric （17） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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7. Citations (1)