6sxo

Cryo-EM structure of the human Ebp1-ribosome complex

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Proliferation-associated protein 2G4

Homo sapiens

UniProt Q9UQ80

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 6 RNA 2 60S ribosomal protein L35 × 1 (P42766) 60S ribosomal protein L38 × 1 (P63173) 60S ribosomal protein L19 × 1 (P84098) 60S ribosomal protein L23a × 1 (P62750) 60S ribosomal protein L26 × 1 (P61254) 28S ribosomal RNA including ES27L-B (2839-3265) × 1 5.8S ribosomal RNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name PA2G4_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A; PDBConstruct 1–394; UniProt 1–394

60S ribosomal protein L35

OrganismNot specified

UniProt P42766

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 6 RNA 2 Proliferation-associated protein 2G4 × 1 (Q9UQ80) 60S ribosomal protein L38 × 1 (P63173) 60S ribosomal protein L19 × 1 (P84098) 60S ribosomal protein L23a × 1 (P62750) 60S ribosomal protein L26 × 1 (P61254) 28S ribosomal RNA including ES27L-B (2839-3265) × 1 5.8S ribosomal RNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RL35_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain Lh; PDBConstruct 1–123; UniProt 1–123

60S ribosomal protein L38

OrganismNot specified

UniProt P63173

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 6 RNA 2 Proliferation-associated protein 2G4 × 1 (Q9UQ80) 60S ribosomal protein L35 × 1 (P42766) 60S ribosomal protein L19 × 1 (P84098) 60S ribosomal protein L23a × 1 (P62750) 60S ribosomal protein L26 × 1 (P61254) 28S ribosomal RNA including ES27L-B (2839-3265) × 1 5.8S ribosomal RNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RL38_HUMAN
Isoform —
PDB entities 3
Chains and sequence ranges Author chain Lk; PDBConstruct 1–70; UniProt 1–70

60S ribosomal protein L19

OrganismNot specified

UniProt P84098

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 6 RNA 2 Proliferation-associated protein 2G4 × 1 (Q9UQ80) 60S ribosomal protein L35 × 1 (P42766) 60S ribosomal protein L38 × 1 (P63173) 60S ribosomal protein L23a × 1 (P62750) 60S ribosomal protein L26 × 1 (P61254) 28S ribosomal RNA including ES27L-B (2839-3265) × 1 5.8S ribosomal RNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RL19_HUMAN
Isoform —
PDB entities 4
Chains and sequence ranges Author chain LR; PDBConstruct 1–196; UniProt 1–196

60S ribosomal protein L23a

OrganismNot specified

UniProt P62750

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 6 RNA 2 Proliferation-associated protein 2G4 × 1 (Q9UQ80) 60S ribosomal protein L35 × 1 (P42766) 60S ribosomal protein L38 × 1 (P63173) 60S ribosomal protein L19 × 1 (P84098) 60S ribosomal protein L26 × 1 (P61254) 28S ribosomal RNA including ES27L-B (2839-3265) × 1 5.8S ribosomal RNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RL23A_HUMAN
Isoform —
PDB entities 5
Chains and sequence ranges Author chain LX; PDBConstruct 1–156; UniProt 1–156

60S ribosomal protein L26

OrganismNot specified

UniProt P61254

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Heteromer Protein 6 RNA 2 Proliferation-associated protein 2G4 × 1 (Q9UQ80) 60S ribosomal protein L35 × 1 (P42766) 60S ribosomal protein L38 × 1 (P63173) 60S ribosomal protein L19 × 1 (P84098) 60S ribosomal protein L23a × 1 (P62750) 28S ribosomal RNA including ES27L-B (2839-3265) × 1 5.8S ribosomal RNA × 1 Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name RL26_HUMAN
Isoform —
PDB entities 6
Chains and sequence ranges Author chain LY; PDBConstruct 1–145; UniProt 1–145

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6sxo
Deposition date deposition_date2019-09-26
Structure title titleCryo-EM structure of the human Ebp1-ribosome complex
Keywords keywordsHuman Ebp1, PA2G4 family, MET-AP homolog, expansion segment ES27L, RIBOSOME; RIBOSOME
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6sxo__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6sxo__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6sxo__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)55.47 Å
Rg (electron density)55.02 Å
Total Rg55.12 Å
Atom count14894
Residues1299
Excluded volume241070 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6sxo__assembly_1__model_1 octameric (8) Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (8)

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7. Citations (1)