← Back to search
6w09

Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain

Method: ELECTRON MICROSCOPY
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

E1 glycoprotein

Chikungunya virus

UniProt Q88628

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 1200 Fab CHK-265 heavy chain × 240 Fab CHK-265 light chain × 240 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 20 Fab CHK-265 heavy chain × 4 Fab CHK-265 light chain × 4 Consistent with protein count
3 Protein heterocomplex Heteromer Protein 100 Fab CHK-265 heavy chain × 20 Fab CHK-265 light chain × 20 Consistent with protein count
4 Protein heterocomplex Heteromer Protein 120 Fab CHK-265 heavy chain × 24 Fab CHK-265 light chain × 24 Consistent with protein count
5 Protein heterocomplex Heteromer Protein 20 Fab CHK-265 heavy chain × 4 Fab CHK-265 light chain × 4 Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers
8fcg

1 assemblies

Heteromeric or nucleic-acid complex
6nk7 6nk7 6nk7 6nk7 6nk7 6w09 6w09 6w09 6w09 6w09 9bbn 9bhh

13 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name Q88628_CHIKV
Isoform —
PDB entities 1, 2, 5
Chains and sequence ranges Author chain A； PDBConstruct 1–393； UniProt 810–1202 Author chain B； PDBConstruct 1–393； UniProt 810–1202 Author chain C； PDBConstruct 1–393； UniProt 810–1202 Author chain D； PDBConstruct 1–393； UniProt 810–1202 Author chain E； PDBConstruct 1–338； UniProt 330–667 Author chain F； PDBConstruct 1–338； UniProt 330–667 Author chain G； PDBConstruct 1–338； UniProt 330–667 Author chain H； PDBConstruct 1–338； UniProt 330–667 Author chain Q； PDBConstruct 1–60； UniProt 266–325 Author chain R； PDBConstruct 1–60； UniProt 266–325 Author chain S； PDBConstruct 1–60； UniProt 266–325 Author chain T； PDBConstruct 1–60； UniProt 266–325

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id6w09
Deposition date deposition_date2020-02-29
Structure title titleHuman mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain
Keywords keywordsvirus, monoclonal antibody, complex, VIRUS-IMMUNE SYSTEM complex; VIRUS/IMMUNE SYSTEM
Experimental Method methodELECTRON MICROSCOPY
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6w09__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6w09__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 1011 1012 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6w09__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）0.00 Å
Rg (electron density)312.10 Å
Total Rg312.10 Å
Atom count1171200
Residues292800
Excluded volume16103000 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6w09__assembly_1__model_1 1200-meric （1200） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 6w09__assembly_2__model_1 eicosameric （20） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
3 1 6w09__assembly_3__model_1 100-meric （100） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
4 1 6w09__assembly_4__model_1 120-meric （120） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
5 1 6w09__assembly_5__model_1 eicosameric （20） Excluded — —
Exclusion reason： Auxiliary symmetry representation; not a complete or representative biological assembly.
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (5)

▶

7. Citations (1)