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6wqu

CSL (RBPJ) bound to Notch3 RAM and DNA

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Recombining binding protein suppressor of hairless

Mus musculus

UniProt P31266

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 2 DNA 2 ;DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*GP*GP*T)-3') ; × 1 ;DNA (5'-D(*TP*TP*AP*CP*CP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3') ; × 1 Neurogenic locus notch homolog protein 3 × 1 （Q9UM47） water × 4 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3brg 3iag 4j2x 4j2x 5eg6 6dks 6dks 6dks 6wqu 7rte 7rti

11 assemblies

View Construct and Data Evidence
UniProt name SUH_MOUSE
Isoform —
PDB entities 3
Chains and sequence ranges Author chain C； PDBConstruct 2–423； UniProt 53–474

Neurogenic locus notch homolog protein 3

Homo sapiens

UniProt Q9UM47

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Heteromer Protein 2 DNA 2 ;DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*GP*GP*T)-3') ; × 1 ;DNA (5'-D(*TP*TP*AP*CP*CP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3') ; × 1 Recombining binding protein suppressor of hairless × 1 （P31266） water × 4 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer
8os0

1 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
4zlp 5czv 5czx 5czx 6wqu 6xsw 6xsw 6xsw 6xsw

9 assemblies

View Construct and Data Evidence
UniProt name NOTC3_HUMAN
Isoform —
PDB entities 4
Chains and sequence ranges Author chain D； PDBConstruct 1–18； UniProt 1665–1682

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id6wqu
Deposition date deposition_date2020-04-29
Structure title titleCSL (RBPJ) bound to Notch3 RAM and DNA
Keywords keywords;Notch signaling, DNA binding protein, transcription factor, activation complex, TRANSCRIPTION, TRANSCRIPTION-SIGNALING PROTEIN-DNA complex ;; TRANSCRIPTION/SIGNALING PROTEIN/DNA
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6wqu__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6wqu__assembly_1__model_1 | I(q)

10-2 10-1 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6wqu__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）27.93 Å
Rg (electron density)26.77 Å
Total Rg27.50 Å
Atom count4026
Residues462
Excluded volume69864 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6wqu__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

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7. Citations (1)