6wrs

Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, tedizolid

Method: ELECTRON MICROSCOPY

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1. Protein Identity and Related Structures Protein Identity & Related Structures

50S ribosomal protein L19

OrganismNot specified

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A077UVB6_STAAU
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–116； UniProt 1–116

50S ribosomal protein L2

OrganismNot specified

UniProt A0A077W1J0

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A077W1J0_STAAU
Isoform	—
PDB entities	2
Chains and sequence ranges	Author chain B； PDBConstruct 1–277； UniProt 1–277

50S ribosomal protein L20

OrganismNot specified

UniProt A0A077VMP6

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A077VMP6_STAAU
Isoform	—
PDB entities	3
Chains and sequence ranges	Author chain C； PDBConstruct 1–118； UniProt 1–118

50S ribosomal protein L21

OrganismNot specified

UniProt A0A0E0VQU6

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A0E0VQU6_STAA5
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain D； PDBConstruct 1–105； UniProt 1–105

uL22

OrganismNot specified

UniProt A7X5F6

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RL22_STAA1
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain E； PDBConstruct 1–117； UniProt 1–117

50S ribosomal protein L23

OrganismNot specified

UniProt W8TUB4

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	W8TUB4_STAAU
Isoform	—
PDB entities	6
Chains and sequence ranges	Author chain F； PDBConstruct 1–91； UniProt 1–91

50S ribosomal protein L24

OrganismNot specified

UniProt W8TRD5

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	W8TRD5_STAAU
Isoform	—
PDB entities	7
Chains and sequence ranges	Author chain G； PDBConstruct 1–105； UniProt 1–105

uL25

OrganismNot specified

UniProt A0A2X2JWH5

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A2X2JWH5_STAAU
Isoform	—
PDB entities	8
Chains and sequence ranges	Author chain H； PDBConstruct 1–107； UniProt 1–107

50S ribosomal protein L28

OrganismNot specified

UniProt A0A077URJ8

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A077URJ8_STAAU
Isoform	—
PDB entities	9
Chains and sequence ranges	Author chain J； PDBConstruct 1–61； UniProt 1–61

50S ribosomal protein L29

OrganismNot specified

UniProt A0A2S6DIY7

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A2S6DIY7_STAAU
Isoform	—
PDB entities	10
Chains and sequence ranges	Author chain K； PDBConstruct 1–72； UniProt 1–72

50S ribosomal protein L3

OrganismNot specified

UniProt W8U3W0

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	W8U3W0_STAAU
Isoform	—
PDB entities	11
Chains and sequence ranges	Author chain L； PDBConstruct 1–217； UniProt 1–217

50S ribosomal protein L30

OrganismNot specified

UniProt W8UVN7

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	W8UVN7_STAAU
Isoform	—
PDB entities	12
Chains and sequence ranges	Author chain M； PDBConstruct 1–58； UniProt 2–59

50S ribosomal protein L32

OrganismNot specified

UniProt A0A077UWR7

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A077UWR7_STAAU
Isoform	—
PDB entities	13
Chains and sequence ranges	Author chain N； PDBConstruct 1–57； UniProt 1–57

50S ribosomal protein L33

OrganismNot specified

UniProt A0A077UXT4

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A077UXT4_STAAU
Isoform	—
PDB entities	14
Chains and sequence ranges	Author chain O； PDBConstruct 1–49； UniProt 1–49

50S ribosomal protein L34

OrganismNot specified

UniProt T1YD75

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	T1YD75_STAAU
Isoform	—
PDB entities	15
Chains and sequence ranges	Author chain P； PDBConstruct 1–50； UniProt 1–50

50S ribosomal protein L35

OrganismNot specified

UniProt A0A077UL47

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A077UL47_STAAU
Isoform	—
PDB entities	16
Chains and sequence ranges	Author chain Q； PDBConstruct 1–65； UniProt 1–65

50S ribosomal protein L36

OrganismNot specified

UniProt A0A077UGV8

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A077UGV8_STAAU
Isoform	—
PDB entities	17
Chains and sequence ranges	Author chain R； PDBConstruct 1–37； UniProt 1–37

50S ribosomal protein L4

OrganismNot specified

UniProt A0A166DK89

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A166DK89_STAAU
Isoform	—
PDB entities	18
Chains and sequence ranges	Author chain S； PDBConstruct 1–207； UniProt 1–207

50S ribosomal protein L13

OrganismNot specified

UniProt W8TUE6

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	W8TUE6_STAAU
Isoform	—
PDB entities	19
Chains and sequence ranges	Author chain V； PDBConstruct 1–145； UniProt 1–145

50S ribosomal protein L14

OrganismNot specified

UniProt A0A077UUA0

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A077UUA0_STAAU
Isoform	—
PDB entities	20
Chains and sequence ranges	Author chain W； PDBConstruct 1–122； UniProt 1–122

50S ribosomal protein L15

OrganismNot specified

UniProt A0A077UGA7

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A077UGA7_STAAU
Isoform	—
PDB entities	21
Chains and sequence ranges	Author chain X； PDBConstruct 1–146； UniProt 1–146

50S ribosomal protein L16

OrganismNot specified

UniProt A0A077V4G0

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A077V4G0_STAAU
Isoform	—
PDB entities	22
Chains and sequence ranges	Author chain Y； PDBConstruct 1–144； UniProt 1–144

50S ribosomal protein L17

OrganismNot specified

UniProt A0A077UG91

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A077UG91_STAAU
Isoform	—
PDB entities	23
Chains and sequence ranges	Author chain Z； PDBConstruct 1–122； UniProt 1–122

50S ribosomal protein L18

OrganismNot specified

UniProt W8TRE0

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 23S rRNA × 1 5S rRNA × 1 50S ribosomal protein L27 × 1 （A0A077ULC5） Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	W8TRE0_STAAU
Isoform	—
PDB entities	24
Chains and sequence ranges	Author chain a； PDBConstruct 1–119； UniProt 1–119

50S ribosomal protein L27

OrganismNot specified

UniProt A0A077ULC5

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein–RNA	Heteromer	Protein 25 RNA 2	50S ribosomal protein L19 × 1 （A0A077UVB6） 50S ribosomal protein L2 × 1 （A0A077W1J0） 50S ribosomal protein L20 × 1 （A0A077VMP6） 50S ribosomal protein L21 × 1 （A0A0E0VQU6） uL22 × 1 （A7X5F6） 50S ribosomal protein L23 × 1 （W8TUB4） 50S ribosomal protein L24 × 1 （W8TRD5） uL25 × 1 （A0A2X2JWH5） 50S ribosomal protein L28 × 1 （A0A077URJ8） 50S ribosomal protein L29 × 1 （A0A2S6DIY7） 50S ribosomal protein L3 × 1 （W8U3W0） 50S ribosomal protein L30 × 1 （W8UVN7） 50S ribosomal protein L32 × 1 （A0A077UWR7） 50S ribosomal protein L33 × 1 （A0A077UXT4） 50S ribosomal protein L34 × 1 （T1YD75） 50S ribosomal protein L35 × 1 （A0A077UL47） 50S ribosomal protein L36 × 1 （A0A077UGV8） 50S ribosomal protein L4 × 1 （A0A166DK89） 50S ribosomal protein L13 × 1 （W8TUE6） 50S ribosomal protein L14 × 1 （A0A077UUA0） 50S ribosomal protein L15 × 1 （A0A077UGA7） 50S ribosomal protein L16 × 1 （A0A077V4G0） 50S ribosomal protein L17 × 1 （A0A077UG91） 50S ribosomal protein L18 × 1 （W8TRE0） 23S rRNA × 1 5S rRNA × 1 Tedizolid × 1	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A077ULC5_STAAU
Isoform	—
PDB entities	27
Chains and sequence ranges	Author chain I； PDBConstruct 1–85； UniProt 10–94

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	6wrs
Deposition date deposition_date	2020-04-30
Structure title title	Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, tedizolid
Keywords keywords	antibiotic, tedizolid, oxazolidinone, RIBOSOME; RIBOSOME
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6wrs__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6wrs__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

6wrs__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	68.13 Å
Rg (electron density)	68.52 Å
Total Rg	68.59 Å
Atom count	81130
Residues	5478
Excluded volume	1223200 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`6wrs__assembly_1__model_1`	27-meric （27）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (28)

Entity 1 Entity 1 polymer

Description description	50S ribosomal protein L19
Molecular weight formula_weight	13392.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A
Atom count atom_count	81130

MTNHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRERIQVFEGVVIKRRGGGVSETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYLRSLRGKAARIQEIR

Entity 2 Entity 2 polymer

Description description	50S ribosomal protein L2
Molecular weight formula_weight	30217.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	B

MAIKKYKPITNGRRNMTSLDFAEITKTTPEKSLLKPLPKKAGRNNQGKLTVRHHGGGHKRQYRVIDFKRNKDGINAKVDSIQYDPNRSANIALVVYADGEKRYIIAPKGLEVGQIVESGAEADIKVGNALPLQNIPVGTVVHNIELKPGKGGQIARSAGASAQVLGKEGKYVLIRLRSGEVRMILSTCRATIGQVGNLQHELVNVGKAGRSRWKGIRPTVRGSVMNPNDHPHGGGEGRAPIGRPSPMSPWGKPTLGKKTRRGKKSSDKLIVRGRKKK

Entity 3 Entity 3 polymer

Description description	50S ribosomal protein L20
Molecular weight formula_weight	13720.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C

MPRVKGGTVTRARRKKTIKLAKGYFGSKHTLYKVAKQQVMKSGQYAFRDRRQRKRDFRKLWITRINAAARQHEMSYSRLMNGLKKAGIDINRKMLSEIAISDEKAFAQLVTKAKDALK

Entity 4 Entity 4 polymer

Description description	50S ribosomal protein L21
Molecular weight formula_weight	11700.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	D

MQSMFAIIETGGKQIKVEEGQEIFVEKLDVNEGDTFTFDKVLFVGGDSVKVGAPTVEGATVTATVNKQGRGKKITVFTYKRRKNSKRKKGHRQPYTKLTIDKINA

Entity 5 Entity 5 polymer

Description description	uL22
Molecular weight formula_weight	12871.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	E

MEAKAVARTIRIAPRKVRLVLDLIRGKNAAEAIAILKLTNKASSPVIEKVLMSALANAEHNYDMNTDELVVKEAYANEGPTLKRFRPRAQGRASAINKRTSHITIVVSDAKEEAKEA

Entity 6 Entity 6 polymer

Description description	50S ribosomal protein L23
Molecular weight formula_weight	10627.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	F

MEARDILKRPVITEKSSEAMAEDKYTFDVDTRVNKTQVKMAVEEIFNVKVASVNIMNYKPKKKRMGRYQGYTNKRRKAIVTLKEGSDDLFN

Entity 7 Entity 7 polymer

Description description	50S ribosomal protein L24
Molecular weight formula_weight	11591.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	G

MHIKKGDNVKVIAGKDKGKEGKVIATLPKKDRVVVEGVNIMKKHQKPTQLNPESGILETEAAIHVSNVQLLDPKTNEPTRVGYKFVDGKKVRIAKKSGEEIKSNN

Entity 8 Entity 8 polymer

Description description	uL25
Molecular weight formula_weight	12063.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	H

MASLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEDVLLKYQFN

Entity 9 Entity 9 polymer

Description description	50S ribosomal protein L28
Molecular weight formula_weight	6967.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	J

MGKQCFVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRA

Entity 10 Entity 10 polymer

Description description	50S ribosomal protein L29
Molecular weight formula_weight	8491.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	K

MKKKKAKEIRNLTTSEIEEQIKSSKEELFNLRFQLATGQLEETARIRTVRKTIARLKTVAREREIEQSKANQ

Entity 11 Entity 11 polymer

Description description	50S ribosomal protein L3
Molecular weight formula_weight	23459.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	L

MTKGILGRKIGMTQVFGENGELIPVTVVEAKENVVLQKKTVEVDGYNAIQVGFEDKKAYKKDAKSNKYANKPAEGHAKKADAAPKRFIREFRNVDVDAYEVGQEVSVDTFVAGDVIDVTGVSKGKGFQGAIKRHGQSRGPMSHGSHFHRAPGSVGMASDASRVFKGQKMPGRMGGNTVTVQNLEVVQVDTENKVILVKGNVPGPKKGLVEIRTSIKK

Entity 12 Entity 12 polymer

Description description	50S ribosomal protein L30
Molecular weight formula_weight	6434.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	M

AKLQITLTRSVIGRPETQRKTVEALGLKKTNSSVVVEDNPAIRGQINKVKHLVTVEEK

Entity 13 Entity 13 polymer

Description description	50S ribosomal protein L32
Molecular weight formula_weight	6472.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	N

MAVPKRRTSKTRKNKRRTHFKISVPGMTECPNCGEYKLSHRVCKNCGSYNGEEAAAK

Entity 14 Entity 14 polymer

Description description	50S ribosomal protein L33
Molecular weight formula_weight	5885.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	O

MRVNVTLACTECGDRNYITTKNKRNNPERVEMKKFCSRENKQTLHRETK

Entity 15 Entity 15 polymer

Description description	50S ribosomal protein L34
Molecular weight formula_weight	6064.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	P

MEVFCMVKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLSA

Entity 16 Entity 16 polymer

Description description	50S ribosomal protein L35
Molecular weight formula_weight	7593.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Q

MPKMKTHRGAAKRVKRTASGQLKRSRAFTSHLFANKSTKQKRQLRKARLVSKSDMKRVKQLLAYK

Entity 17 Entity 17 polymer

Description description	50S ribosomal protein L36
Molecular weight formula_weight	4318.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	R

MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQRQG

Entity 18 Entity 18 polymer

Description description	50S ribosomal protein L4
Molecular weight formula_weight	22523.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	S

MANYDVLKLDGTKSGSIELSDAVFGIEPNNSVLFEAINLQRASLRQGTHAVKNRSAVSGGGRKPWKQKGTGRARQGTIRAPQWRGGGIVFGPTPRSYAYKMPKKMRRLALRSALSFKVQENGLTVVDAFNFEAPKTKEFKNVLSTLEQPKKVLVVTENEDVNVELSARNIPGVQVTTAQGLNVLDITNADSLVITEAAAKKVEEVLG

Entity 19 Entity 19 polymer

Description description	50S ribosomal protein L13
Molecular weight formula_weight	16359.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	V

MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKVTYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG

Entity 20 Entity 20 polymer

Description description	50S ribosomal protein L14
Molecular weight formula_weight	13157.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	W

MIQQETRLKVADNSGAREVLTIKVLGGSGRKTANIGDVIVCTVKNATPGGVVKKGDVVKAVIVRTKSGVRRNDGSYIKFDENACVIIRDDKGPRGTRIFGPVARELREGNFMKIVSLAPEVL

Entity 21 Entity 21 polymer

Description description	50S ribosomal protein L15
Molecular weight formula_weight	15628.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	X

MKLHELKPAEGSRKERNRVGRGVATGNGKTSGRGHKGQKARSGGGVRPGFEGGQLPLFRRLPKRGFTNINRKEYAIVNLDQLNKFEDGTEVTPALLVESGVVKNEKSGIKILGNGSLDKKLTVKAHKFSASAAEAIDAKGGAHEVI

Entity 22 Entity 22 polymer

Description description	50S ribosomal protein L16
Molecular weight formula_weight	16274.0 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Y

MLLPKRVKYRRQHRPKTTGRSKGGNYVTFGEFGLQATTTSWITSRQIESARIAMTRYMKRGGKVWIKIFPHTPYTKKPLEVRMGAGKGAVEGWIAVVKPGRILFEVAGVSEEVAREALRLASHKLPVKTKFVKREELGGETNES

Entity 23 Entity 23 polymer

Description description	50S ribosomal protein L17
Molecular weight formula_weight	13771.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Z

MGYRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRSVVEKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTALQKLFGEIAERYTERQGGYTRILKQGPRRGDGAESVIIELV

Entity 24 Entity 24 polymer

Description description	50S ribosomal protein L18
Molecular weight formula_weight	13124.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	a

MISKIDKNKVRLKRHARVRTNLSGTAEKPRLNVYRSNKHIYAQIIDDNKGVTLAQASSKDSDIATTATKVELATKVGEAIAKKAADKGIKEIVFDRGGYLYHGRVKALAEAARESGLEF

Entity 25 Entity 25 polymer

Description description	23S rRNA
Molecular weight formula_weight	946680.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	1

GAUUAAGUUAUUAAGGGCGCACGGUGGAUGCCUUGGCACUAGAAGCCGAUGAAGGACGUUACUAACGACGAUAUGCUUUGGGGAGCUGUAAGUAAGCUUUGAUCCAGAGAUUUCCGAAUGGGGAAACCCAGCAUGAGUUAUGUCAUGUUAUCGAUAUGUGAAUACAUAGCAUAUCAGAAGGCACACCCGGAGAACUGAAACAUCUUAGUACCCGGAGGAAGAGAAAGAAAAUUCGAUUCCCUUAGUAGCGGCGAGCGAAACGGGAAGAGCCCAAACCAACAAGCUUGCUUGUUGGGGUUGUAGGACACUCUAUACGGAGUUACAAAGGACGACAUUAGACGAAUCAUCUGGAAAGAUGAAUCAAAGAAGGUAAUAAUCCUGUAGUCGAAAAUGUUGUCUCUCUUGAGUGGAUCCUGAGUACGACGGAGCACGUGAAAUUCCGUCGGAAUCUGGGAGGACCAUCUCCUAAGGCUAAAUACUCUCUAGUGACCGAUAGUGAACCAGUACCGUGAGGGAAAGGUGAAAAGCACCCCGGAAGGGGAGUGAAAUAGAACCUGAAACCGUGUGCUUACAAGUAGUCAGAGCCCGUUAAUGGGUGAUGGCGUGCCUUUUGUAGAAUGAACCGGCGAGUUACGAUUUGAUGCAAGGUUAAGCAGUAAAUGUGGAGCCGUAGCGAAAGCGAGUCUGAAUAGGGCGUUUAGUAUUUGGUCGUAGACCCGAAACCAGGUGAUCUACCCUUGGUCAGGUUGAAGUUCAGGUAACACUGAAUGGAGGACCGAACCGACUUACGUUGAAAAGUGAGCGGAUGAACUGAGGGUAGCGGAGAAAUUCCAAUCGAACCUGGAGAUAGCUGGUUCUCUCCGAAAUAGCUUUAGGGCUAGCCUCAAGUGAUGAUUAUUGGAGGUAGAGCACUGUUUGGACGAGGGGCCCCUCUCGGGUUACCGAAUUCAGACAAACUCCGAAUGCCAAUUAAUUUAACUUGGGAGUCAGAACAUGGGUGAUAAGGUCCGUGUUCGAAAGGGAAACAGCCCAGACCACCAGCUAAGGUCCCAAAAUAUAUGUUAAGUGGAAAAGGAUGUGGCGUUGCCCAGACAACUAGGAUGUUGGCUUAGAAGCAGCCAUCAUUUAAAGAGUGCGUAAUAGCUCACUAGUCGAGUGACACUGCGCCGAAAAUGUACCGGGGCUAAACAUAUUACCGAAGCUGUGGAUUGUCCUUUGGACAAUGGUAGGAGAGCGUUCUAAGGGCGUUGAAGCAUGAUCGUAAGGACAUGUGGAGCGCUUAGAAGUGAGAAUGCCGGUGUGAGUAGCGAAAGACGGGUGAGAAUCCCGUCCACCGAUUGACUAAGGUUUCCAGAGGAAGGCUCGUCCGCUCUGGGUUAGUCGGGUCCUAAGCUGAGGCCGACAGGCGUAGGCGAUGGAUAACAGGUUGAUAUUCCUGUACCACCUAUAAUCGUUUUAAUCGAUGGGGGGACGCAGUAGGAUAGGCGAAGCGUGCGAUUGGAUUGCACGUCUAAGCAGUAAGGCUGAGUAUUAGGCAAAUCCGGUACUCGUUAAGGCUGAGCUGUGAUGGGGAGAAGACAUUGUGUCUUCGAGUCGUUGAUUUCACACUGCCGAGAAAAGCCUCUAGAUAGAAAAUAGGUGCCCGUACCGCAAACCGACACAGGUAGUCAAGAUGAGAAUUCUAAGGUGAGCGAGCGAACUCUCGUUAAGGAACUCGGCAAAAUGACCCCGUAACUUCGGGAGAAGGGGUGCUCUUUAGGGUUAACGCCCAGAAGAGCCGCAGUGAAUAGGCCCAAGCGACUGUUUAUCAAAAACACAGGUCUCUGCUAAACCGUAAGGUGAUGUAUAGGGGCUGACGCCUGCCCAGUGCUGGAAGGUUAAGAGGAGUGGUUAGCUUCUGCGAAGCUACGAAUCGAAGCCCCAGUAAACGGCGGCCGUAACUAUAACGGUCCUAAGGUAGCGAAAUUCCUUGUCGGGUAAGUUCCGACCCGCACGAAAGGCGUAACGAUUUGGGCACUGUCUCAACGAGAGACUCGGUGAAAUCAUAGUACCUGUGAAGAUGCAGGUUACCCGCGACAGGACGGAAAGACCCCGUGGAGCUUUACUGUAGCCUGAUAUUGAAAUUCGGCACAGCUUGUACAGGAUAGGUAGGAGCCUUUGAAACGUGAGCGCUAGCUUACGUGGAGGCGCUGGUGGGAUACUACCCUAGCUGUGUUGGCUUUCUAACCCGCACCACUUAUCGUGGUGGGAGACAGUGUCAGGCGGGCAGUUUGACUGGGGCGGUCGCCUCCUAAAAGGUAACGGAGGCGCUCAAAGGUUCCCUCAGAAUGGUUGGAAAUCAUUCAUAGAGUGUAAAGGCAUAAGGGAGCUUGACUGCGAGACCUACAAGUCGAGCAGGGUCGAAAGACGGACUUAGUGAUCCGGUGGUUCCGCAUGGAAGGGCCAUCGCUCAACGGAUAAAAGCUACCCCGGGGAUAACAGGCUUAUCUCCCCCAAGAGUUCACAUCGACGGGGAGGUUUGGCACCUCGAUGUCGGCUCAUCGCAUCCUGGGGCUGUAGUCGGUCCCAAGGGUUGGGCUGUUCGCCCAUUAAAGCGGUACGCGAGCUGGGUUCAGAACGUCGUGAGACAGUUCGGUCCCUAUCCGUCGUGGGCGUAGGAAAUUUGAGAGGAGCUGUCCUUAGUACGAGAGGACCGGGAUGGACAUACCUCUGGUGUACCAGUUGUCGUGCCAACGGCAUAGCUGGGUAGCUAUGUGUGGACGGGAUAAGUGCUGAAAGCAUCUAAGCAUGAAGCCCCCCUCAAGAUGAGAUUUCCCAACUUCGGUUAUAAGAUCCCUCAAAGAUGAUGAGGUUAAUAGGUUCGAGGUGGAAGCAUGGUGACAUGUGGAGCUGACGAAUACUAAUCGAUCGAAGACUUAAUCAA

Entity 26 Entity 26 polymer

Description description	5S rRNA
Molecular weight formula_weight	36958.0 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	2

UCUGGUGACUAUAGCAAGGAGGUCACACCUGUUCCCAUGCCGAACACAGAAGUUAAGCUCCUUAGCGACGAUGGUAGUCCAACUUACGUUCCGCUAGAGUAGAACGUUCCAGGGC

Entity 27 Entity 27 polymer

Description description	50S ribosomal protein L27
Molecular weight formula_weight	9198.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	I

ASKKGVSSTKNGRDSESKRLGAKRADGQFVTGGSILYRQRGTKIYPGENVGRGGDDTLFAKIDGVVKFERKGRDKKQVSVYAVAE

Entity 28 Entity 28 non-polymer

Description description	Tedizolid
Molecular weight formula_weight	370.3 kDa
Source method src_method	syn
Copy count entity_count	1

▼

6. Fold Classification (SCOP + CATH) 11 domains

CATH v4.4 (11 domains)

Domain ID domain_id	6wrsE00
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	470 — Ribosomal Protein L22; Chain A
Homologous superfamily homologous superfamily	10 — Ribosomal protein L22/L17

Domain ID domain_id	6wrsF00
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	70 — Alpha-Beta Plaits
Homologous superfamily homologous superfamily	330 — RRM (RNA recognition motif) domain

Domain ID domain_id	6wrsH01
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	240 — Ribosomal Protein L25; Chain P
Homologous superfamily homologous superfamily	10 — Ribosomal Protein L25; Chain P

Domain ID domain_id	6wrsM00
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	1390 — Ribosomal Protein L30; Chain: A,
Homologous superfamily homologous superfamily	20 — Ribosomal protein L30/L7

Domain ID domain_id	6wrsO00
Class class	2 — Mainly Beta
Architecture architecture	20 — Single Sheet
Topology topology	28 — Rubrerythrin, domain 2
Homologous superfamily homologous superfamily	120 — Ribosomal protein L33

Domain ID domain_id	6wrsP00
Class class	1 — Mainly Alpha
Architecture architecture	10 — Orthogonal Bundle
Topology topology	287 — Helix Hairpins
Homologous superfamily homologous superfamily	3980 —

Domain ID domain_id	6wrsW00
Class class	2 — Mainly Beta
Architecture architecture	40 — Beta Barrel
Topology topology	150 — Ribosomal Protein L14
Homologous superfamily homologous superfamily	20 — Ribosomal protein L14/L23

Domain ID domain_id	6wrsX01
Class class	3 — Alpha Beta
Architecture architecture	100 — Ribosomal Protein L15; Chain: K; domain 2
Topology topology	10 — Ribosomal Protein L15; Chain: K; domain 2
Homologous superfamily homologous superfamily	10 —

Domain ID domain_id	6wrsY01
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1170 — Aldehyde Oxidoreductase; domain 3
Homologous superfamily homologous superfamily	10 — Ribosomal protein L16/L10

Domain ID domain_id	6wrsZ00
Class class	3 — Alpha Beta
Architecture architecture	90 — Alpha-Beta Complex
Topology topology	1030 — 50s Ribosomal Protein L17; Chain: A,
Homologous superfamily homologous superfamily	10 — Ribosomal protein L17

Domain ID domain_id	6wrsa01
Class class	3 — Alpha Beta
Architecture architecture	30 — 2-Layer Sandwich
Topology topology	420 — Nucleotidyltransferase; domain 5
Homologous superfamily homologous superfamily	100 —

▶

Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	—

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	—

Resolution resolution	3.20 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	140000

Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, tedizolid

1. Protein Identity and Related Structures Protein Identity & Related Structures

50S ribosomal protein L19

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

50S ribosomal protein L2

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

50S ribosomal protein L20

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

50S ribosomal protein L21

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

uL22

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

50S ribosomal protein L23

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

50S ribosomal protein L24

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

uL25

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

50S ribosomal protein L28

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

50S ribosomal protein L29

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer