SAXSdb — 6xkj

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Caspase recruitment domain-containing protein 8

Homo sapiens

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Protein homooligomer	Homooligomer	Protein 16	No other associated polymer	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	CARD8_HUMAN
Isoform	Q9Y2G2-5
PDB entities	1
Chains and sequence ranges	Author chain A； PDBConstruct 1–87； UniProt 451–537 Author chain B； PDBConstruct 1–87； UniProt 451–537 Author chain C； PDBConstruct 1–87； UniProt 451–537 Author chain D； PDBConstruct 1–87； UniProt 451–537 Author chain E； PDBConstruct 1–87； UniProt 451–537 Author chain F； PDBConstruct 1–87； UniProt 451–537 Author chain G； PDBConstruct 1–87； UniProt 451–537 Author chain H； PDBConstruct 1–87； UniProt 451–537 Author chain I； PDBConstruct 1–87； UniProt 451–537 Author chain J； PDBConstruct 1–87； UniProt 451–537 Author chain K； PDBConstruct 1–87； UniProt 451–537 Author chain L； PDBConstruct 1–87； UniProt 451–537 Author chain M； PDBConstruct 1–87； UniProt 451–537 Author chain N； PDBConstruct 1–87； UniProt 451–537 Author chain O； PDBConstruct 1–87； UniProt 451–537 Author chain P； PDBConstruct 1–87； UniProt 451–537

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	6xkj
Deposition date deposition_date	2020-06-26
Structure title title	Cryo-EM structure of CARD8-CARD filament
Keywords keywords	Filament, inflammasome, signaling, UPA, FIIND, CARD, NLRP1, IMMUNE SYSTEM; IMMUNE SYSTEM
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6xkj__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6xkj__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

6xkj__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	35.43 Å
Rg (electron density)	34.77 Å
Total Rg	35.19 Å
Atom count	11056
Residues	1360
Excluded volume	195600 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`6xkj__assembly_1__model_1`	hexadecameric （16）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	—

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	—

Resolution resolution	3.54 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	111333

Description description	Caspase recruitment domain-containing protein 8
Molecular weight formula_weight	10103.4 kDa
Source method src_method	man
Copy count entity_count	16

Polymer type type	polypeptide(L)
Chain IDs strand_id	C,A,B,D,E,F,G,H,I,J,K,L,M,N,O,P
Atom count atom_count	11056

Cryo-EM structure of CARD8-CARD filament

1. Protein Identity and Related Structures Protein Identity & Related Structures

Caspase recruitment domain-containing protein 8

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

6xkj__assembly_1__model_1

6xkj__assembly_1__model_1 | I(q)

6xkj__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

冷冻电镜 EM 3D

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

7. Citations (1)

Source organism organism	Homo sapiens
Common name common_name	Human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Escherichia coli

Cryo-EM structure of CARD8-CARD filament

1. Protein Identity and Related Structures Protein Identity & Related Structures

Caspase recruitment domain-containing protein 8

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

6xkj__assembly_1__model_1

6xkj__assembly_1__model_1 | I(q)

6xkj__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

冷冻电镜 EM 3D

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

7. Citations (1)