← Back to search
6xrv

X-ray structure of the monoclinic crystal form at 1.43 A resolution of lipase from Thermomyces (Humicola) lanuginosa at 173 K

Method: X-RAY DIFFRACTION
▼

1. Protein Identity and Related Structures Protein Identity & Related Structures

Lipase

Thermomyces lanuginosus

UniProt O59952

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein homooligomer Homooligomer Protein 3 OCTANOIC ACID (CAPRYLIC ACID) × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 2-hydroxy-3-(octadecanoyloxy)propyl pentacosanoate × 3 PHOSPHATE ION × 5 CALCIUM ION × 2 water × 3 Consistent with protein count
2 Protein homooligomer Homooligomer Protein 3 OCTANOIC ACID (CAPRYLIC ACID) × 3 2-acetamido-2-deoxy-beta-D-glucopyranose × 3 2-hydroxy-3-(octadecanoyloxy)propyl pentacosanoate × 3 PHOSPHATE ION × 4 CALCIUM ION × 4 water × 3 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1dt3 1dt3 1dt5 1dt5 1dt5 1dt5 1dt5 1dt5 1dt5 1dt5 1dte 1dte

26 assemblies; showing the first 12

Homodimer
4dyh 4ea6 4flf 4gbg 4ghw 4gi1 4glb 4gwl 4kjx 4n8s 4s0x 4zgb

15 assemblies; showing the first 12

Homotetramer
6or3

1 assemblies

Other homooligomers
6o8v 6o9f 6o9f 6osz 6osz 6xok 6xrv 6xrv 6xs3 6xs3

10 assemblies

Heteromeric or nucleic-acid complex

None

View Construct and Data Evidence
UniProt name LIP_THELA
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–291； UniProt 1–291 Author chain B； PDBConstruct 1–291； UniProt 1–291 Author chain C； PDBConstruct 1–291； UniProt 1–291 Author chain D； PDBConstruct 1–291； UniProt 1–291 Author chain E； PDBConstruct 1–291； UniProt 1–291 Author chain F； PDBConstruct 1–291； UniProt 1–291

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

▼

2. Structure Basics 2. Structure Basics

Entry ID entry_id6xrv
Deposition date deposition_date2020-07-13
Structure title titleX-ray structure of the monoclinic crystal form at 1.43 A resolution of lipase from Thermomyces (Humicola) lanuginosa at 173 K
Keywords keywordssubstrate complex, diacylglycerol, covalent intermediate, interfacial activation, LIPID BINDING PROTEIN; LIPID BINDING PROTEIN
Experimental Method methodX-RAY DIFFRACTION
▼

3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

6xrv__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

6xrv__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

6xrv__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）29.04 Å
Rg (electron density)27.73 Å
Total Rg28.54 Å
Atom count12358
Residues807
Excluded volume113710 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 6xrv__assembly_1__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 6xrv__assembly_2__model_1 trimeric （3） Success 4.1.3-1-20251215 (887e7ef) View Download
▶

4. Crystallography and Experiment 4. Crystallography & Experiment

▶

5. Entities and Polymers Entities & Polymers (7)

▼

6. Fold Classification (SCOP + CATH) 6 domains

SCOP 2.08 (6 domains)

Domain ID domain_idd6xrva_
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.69 — alpha/beta-Hydrolases
Superfamily Superfamily superfamilyc.69.1 — alpha/beta-Hydrolases
Family Family familyc.69.1.17 — Fungal lipases
Domain ID domain_idd6xrvb_
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.69 — alpha/beta-Hydrolases
Superfamily Superfamily superfamilyc.69.1 — alpha/beta-Hydrolases
Family Family familyc.69.1.17 — Fungal lipases
Domain ID domain_idd6xrvc_
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.69 — alpha/beta-Hydrolases
Superfamily Superfamily superfamilyc.69.1 — alpha/beta-Hydrolases
Family Family familyc.69.1.17 — Fungal lipases
Domain ID domain_idd6xrvd_
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.69 — alpha/beta-Hydrolases
Superfamily Superfamily superfamilyc.69.1 — alpha/beta-Hydrolases
Family Family familyc.69.1.17 — Fungal lipases
Domain ID domain_idd6xrve_
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.69 — alpha/beta-Hydrolases
Superfamily Superfamily superfamilyc.69.1 — alpha/beta-Hydrolases
Family Family familyc.69.1.17 — Fungal lipases
Domain ID domain_idd6xrvf_
Class classc — Alpha and beta proteins (a/b)
Fold Fold foldc.69 — alpha/beta-Hydrolases
Superfamily Superfamily superfamilyc.69.1 — alpha/beta-Hydrolases
Family Family familyc.69.1.17 — Fungal lipases
▶

7. Citations (1)