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7au3

Cytochrome c oxidase structure in F-state

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Cytochrome c oxidase subunit 1-beta

OrganismNot specified

UniProt P98002

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 4 PDB declaration: tetrameric（4） Consistent with protein copy count Chain A； UniProt 1–558 Not recorded Cytochrome c oxidase subunit 2 × 1 （P08306） Cytochrome c oxidase subunit 3 × 1 （P06030） Cytochrome c oxidase subunit 4 × 1 （P77921） MN MANGANESE (II) ION × 1 HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 O OXYGEN ATOM × 1 2FK SUPEROXO ION × 1 CUA DINUCLEAR COPPER ION × 1 PGV (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE × 1 ELECTRON MICROSCOPY cryo-EM buffer：pH 8 cryo-EM vitrification conditions：Cryogen ETHANE；4 seconds before plunging Resolution 2.56 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 7AU3 Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
1AR1 Structure at 2.7 Angstrom Resolution of the Paracoccus Denitrificans two-subunit Cytochrome C Oxidase Complexed with an Antibody Fv Fragment Deposited 1997-08-08 Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain A 1–558（558 aa）
Not recorded CU COPPER (II) ION × 3 MG MAGNESIUM ION × 1 CA CALCIUM ION × 1 HEA HEME-A × 2 LDA LAURYL DIMETHYLAMINE-N-OXIDE × 9 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 2.70 Å R-free 0.261
1QLE CRYO-STRUCTURE OF THE PARACOCCUS DENITRIFICANS FOUR-SUBUNIT CYTOCHROME C OXIDASE IN THE COMPLETELY OXIDIZED STATE COMPLEXED WITH AN ANTIBODY FV FRAGMENT Deposited 1999-08-30 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric
Chain A 17–554（538 aa）
Not recorded HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 MN MANGANESE (II) ION × 1 CUA DINUCLEAR COPPER ION × 1 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；pH 8.00
Resolution 3.00 Å R-free 0.309
3EHB A D-Pathway Mutation Decouples the Paracoccus Denitrificans Cytochrome c Oxidase by Altering the side chain orientation of a distant, conserved Glutamate Deposited 2008-09-12 Different construct Different mutation/modification Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain A 1–558（558 aa） Fragment：UNP residues 17-545
Mutation：N131D HEA HEME-A × 2 CU COPPER (II) ION × 3 MG MAGNESIUM ION × 1 CA CALCIUM ION × 1 LDA LAURYL DIMETHYLAMINE-N-OXIDE × 9 LMT DODECYL-BETA-D-MALTOSIDE × 12 PER PEROXIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.3；291 K；MPEG 2000 is contained in the crystallization buffer pH 5.5, pH 7.3, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.32 Å R-free 0.242
3HB3 High resolution crystal structure of Paracoccus denitrificans cytochrome c oxidase Deposited 2009-05-04 Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain A 1–558（558 aa）
Not recorded HEA HEME-A × 2 CU1 COPPER (I) ION × 3 MN MANGANESE (II) ION × 1 CA CALCIUM ION × 1 LDA LAURYL DIMETHYLAMINE-N-OXIDE × 10 LMT DODECYL-BETA-D-MALTOSIDE × 14 PEO HYDROGEN PEROXIDE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 5.5；277 K；25% glycerol, pH 5.5, VAPOR DIFFUSION, temperature 277K
Resolution 2.25 Å R-free 0.280
7ATE Cytochrome c oxidase structure in P-state Deposited 2020-10-30 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain A 1–558（558 aa）
Not recorded MN MANGANESE (II) ION × 1 HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 PEO HYDROGEN PEROXIDE × 1 CUA DINUCLEAR COPPER ION × 1 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 1 PGV (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE；4 second before plunging
Resolution 2.40 Å
7ATN Cytochrome c oxidase structure in R-state Deposited 2020-10-30 Different ligand/ion Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain A 1–558（558 aa）
Not recorded MN MANGANESE (II) ION × 1 HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 CUA DINUCLEAR COPPER ION × 1 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE；4 seconds before plunging
Resolution 2.66 Å
7AU6 Cytochrome c oxidase structure in O-state Deposited 2020-11-02 Different ligand/ion Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain A 1–558（558 aa）
Not recorded HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 OXY OXYGEN MOLECULE × 6 PEO HYDROGEN PEROXIDE × 1 MN MANGANESE (II) ION × 1 CUA DINUCLEAR COPPER ION × 1 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE；4 seconds before plunging
Resolution 2.40 Å

7 other PDB entries and 7 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name COX1B_PARDE
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–558； UniProt 1–558

Cytochrome c oxidase subunit 2

OrganismNot specified

UniProt P08306

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 4 PDB declaration: tetrameric（4） Consistent with protein copy count Chain B； UniProt 1–298 Not recorded Cytochrome c oxidase subunit 1-beta × 1 （P98002） Cytochrome c oxidase subunit 3 × 1 （P06030） Cytochrome c oxidase subunit 4 × 1 （P77921） MN MANGANESE (II) ION × 1 HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 O OXYGEN ATOM × 1 2FK SUPEROXO ION × 1 CUA DINUCLEAR COPPER ION × 1 PGV (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE × 1 ELECTRON MICROSCOPY cryo-EM buffer：pH 8 cryo-EM vitrification conditions：Cryogen ETHANE；4 seconds before plunging Resolution 2.56 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 7AU3 Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
1AR1 Structure at 2.7 Angstrom Resolution of the Paracoccus Denitrificans two-subunit Cytochrome C Oxidase Complexed with an Antibody Fv Fragment Deposited 1997-08-08 Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain B 1–298（298 aa）
Not recorded CU COPPER (II) ION × 3 MG MAGNESIUM ION × 1 CA CALCIUM ION × 1 HEA HEME-A × 2 LDA LAURYL DIMETHYLAMINE-N-OXIDE × 9 X-RAY DIFFRACTION
X-ray crystallization conditions pH 5.5；pH 5.5
Resolution 2.70 Å R-free 0.261
1QLE CRYO-STRUCTURE OF THE PARACOCCUS DENITRIFICANS FOUR-SUBUNIT CYTOCHROME C OXIDASE IN THE COMPLETELY OXIDIZED STATE COMPLEXED WITH AN ANTIBODY FV FRAGMENT Deposited 1999-08-30 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric
Chain B 30–281（252 aa）
Not recorded HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 MN MANGANESE (II) ION × 1 CUA DINUCLEAR COPPER ION × 1 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；pH 8.00
Resolution 3.00 Å R-free 0.309
3EHB A D-Pathway Mutation Decouples the Paracoccus Denitrificans Cytochrome c Oxidase by Altering the side chain orientation of a distant, conserved Glutamate Deposited 2008-09-12 Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain B 1–298（298 aa）
Not recorded HEA HEME-A × 2 CU COPPER (II) ION × 3 MG MAGNESIUM ION × 1 CA CALCIUM ION × 1 LDA LAURYL DIMETHYLAMINE-N-OXIDE × 9 LMT DODECYL-BETA-D-MALTOSIDE × 12 PER PEROXIDE ION × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION, HANGING DROP；pH 7.3；291 K；MPEG 2000 is contained in the crystallization buffer pH 5.5, pH 7.3, VAPOR DIFFUSION, HANGING DROP, temperature 291K
Resolution 2.32 Å R-free 0.242
3HB3 High resolution crystal structure of Paracoccus denitrificans cytochrome c oxidase Deposited 2009-05-04 Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain B 1–298（298 aa）
Not recorded HEA HEME-A × 2 CU1 COPPER (I) ION × 3 MN MANGANESE (II) ION × 1 CA CALCIUM ION × 1 LDA LAURYL DIMETHYLAMINE-N-OXIDE × 10 LMT DODECYL-BETA-D-MALTOSIDE × 14 PEO HYDROGEN PEROXIDE × 1 X-RAY DIFFRACTION
X-ray crystallization conditions VAPOR DIFFUSION；pH 5.5；277 K；25% glycerol, pH 5.5, VAPOR DIFFUSION, temperature 277K
Resolution 2.25 Å R-free 0.280
7ATE Cytochrome c oxidase structure in P-state Deposited 2020-10-30 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain B 1–298（298 aa）
Not recorded MN MANGANESE (II) ION × 1 HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 PEO HYDROGEN PEROXIDE × 1 CUA DINUCLEAR COPPER ION × 1 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 1 PGV (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE；4 second before plunging
Resolution 2.40 Å
7ATN Cytochrome c oxidase structure in R-state Deposited 2020-10-30 Different ligand/ion Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain B 1–298（298 aa）
Not recorded MN MANGANESE (II) ION × 1 HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 CUA DINUCLEAR COPPER ION × 1 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE；4 seconds before plunging
Resolution 2.66 Å
7AU6 Cytochrome c oxidase structure in O-state Deposited 2020-11-02 Different ligand/ion Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain B 1–298（298 aa）
Not recorded HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 OXY OXYGEN MOLECULE × 6 PEO HYDROGEN PEROXIDE × 1 MN MANGANESE (II) ION × 1 CUA DINUCLEAR COPPER ION × 1 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE；4 seconds before plunging
Resolution 2.40 Å

7 other PDB entries and 7 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name COX2_PARDE
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–298； UniProt 1–298

Cytochrome c oxidase subunit 3

OrganismNot specified

UniProt P06030

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 4 PDB declaration: tetrameric（4） Consistent with protein copy count Chain C； UniProt 1–274 Not recorded Cytochrome c oxidase subunit 1-beta × 1 （P98002） Cytochrome c oxidase subunit 2 × 1 （P08306） Cytochrome c oxidase subunit 4 × 1 （P77921） MN MANGANESE (II) ION × 1 HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 O OXYGEN ATOM × 1 2FK SUPEROXO ION × 1 CUA DINUCLEAR COPPER ION × 1 PGV (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE × 1 ELECTRON MICROSCOPY cryo-EM buffer：pH 8 cryo-EM vitrification conditions：Cryogen ETHANE；4 seconds before plunging Resolution 2.56 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 7AU3 Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
1QLE CRYO-STRUCTURE OF THE PARACOCCUS DENITRIFICANS FOUR-SUBUNIT CYTOCHROME C OXIDASE IN THE COMPLETELY OXIDIZED STATE COMPLEXED WITH AN ANTIBODY FV FRAGMENT Deposited 1999-08-30 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric
Chain C 1–273（273 aa）
Not recorded HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 MN MANGANESE (II) ION × 1 CUA DINUCLEAR COPPER ION × 1 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；pH 8.00
Resolution 3.00 Å R-free 0.309
7ATE Cytochrome c oxidase structure in P-state Deposited 2020-10-30 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain C 1–274（274 aa）
Not recorded MN MANGANESE (II) ION × 1 HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 PEO HYDROGEN PEROXIDE × 1 CUA DINUCLEAR COPPER ION × 1 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 1 PGV (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE；4 second before plunging
Resolution 2.40 Å
7ATN Cytochrome c oxidase structure in R-state Deposited 2020-10-30 Different ligand/ion Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain C 1–274（274 aa）
Not recorded MN MANGANESE (II) ION × 1 HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 CUA DINUCLEAR COPPER ION × 1 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE；4 seconds before plunging
Resolution 2.66 Å
7AU6 Cytochrome c oxidase structure in O-state Deposited 2020-11-02 Different ligand/ion Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain C 1–274（274 aa）
Not recorded HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 OXY OXYGEN MOLECULE × 6 PEO HYDROGEN PEROXIDE × 1 MN MANGANESE (II) ION × 1 CUA DINUCLEAR COPPER ION × 1 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE；4 seconds before plunging
Resolution 2.40 Å

4 other PDB entries and 4 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name COX3_PARDE
Isoform —
PDB entities 3
Chains and sequence ranges Author chain C； PDBConstruct 1–274； UniProt 1–274

Cytochrome c oxidase subunit 4

OrganismNot specified

UniProt P77921

State in the Current Structure

Assembly Oligomeric State Construct Mutations and Modifications Ligands, Ions and Associated Components Method and Experimental Conditions Structure Quality
1 Protein heterocomplex Heteromer Protein × 4 PDB declaration: tetrameric（4） Consistent with protein copy count Chain D； UniProt 1–50 Not recorded Cytochrome c oxidase subunit 1-beta × 1 （P98002） Cytochrome c oxidase subunit 2 × 1 （P08306） Cytochrome c oxidase subunit 3 × 1 （P06030） MN MANGANESE (II) ION × 1 HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 O OXYGEN ATOM × 1 2FK SUPEROXO ION × 1 CUA DINUCLEAR COPPER ION × 1 PGV (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE × 1 ELECTRON MICROSCOPY cryo-EM buffer：pH 8 cryo-EM vitrification conditions：Cryogen ETHANE；4 seconds before plunging Resolution 2.56 Å

Other States of the Same Protein in the Database

Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.

Other PDB Difference from Current Entry 7AU3 Assembly / Oligomeric State Construct Mutations and Modifications Ligands, Ions and Non-polymers Method and Experimental Conditions Structure Quality
1QLE CRYO-STRUCTURE OF THE PARACOCCUS DENITRIFICANS FOUR-SUBUNIT CYTOCHROME C OXIDASE IN THE COMPLETELY OXIDIZED STATE COMPLEXED WITH AN ANTIBODY FV FRAGMENT Deposited 1999-08-30 Different construct Different oligomeric state Different ligand/ion Different experimental method Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 6 PDB declaration: hexameric
Chain D 8–50（43 aa）
Not recorded HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 MN MANGANESE (II) ION × 1 CUA DINUCLEAR COPPER ION × 1 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 X-RAY DIFFRACTION
X-ray crystallization conditions pH 8；pH 8.00
Resolution 3.00 Å R-free 0.309
7ATE Cytochrome c oxidase structure in P-state Deposited 2020-10-30 Different ligand/ion Different experimental conditions Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain D 1–50（50 aa）
Not recorded MN MANGANESE (II) ION × 1 HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 PEO HYDROGEN PEROXIDE × 1 CUA DINUCLEAR COPPER ION × 1 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 1 PGV (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE；4 second before plunging
Resolution 2.40 Å
7ATN Cytochrome c oxidase structure in R-state Deposited 2020-10-30 Different ligand/ion Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain D 1–50（50 aa）
Not recorded MN MANGANESE (II) ION × 1 HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 CUA DINUCLEAR COPPER ION × 1 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 1 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE；4 seconds before plunging
Resolution 2.66 Å
7AU6 Cytochrome c oxidase structure in O-state Deposited 2020-11-02 Different ligand/ion Different structure-quality metrics Assembly 1 Protein heterocomplex Heteromer；Protein × 4 PDB declaration: tetrameric
Chain D 1–50（50 aa）
Not recorded HEA HEME-A × 2 CU COPPER (II) ION × 1 CA CALCIUM ION × 1 OXY OXYGEN MOLECULE × 6 PEO HYDROGEN PEROXIDE × 1 MN MANGANESE (II) ION × 1 CUA DINUCLEAR COPPER ION × 1 PC1 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE × 2 ELECTRON MICROSCOPY
cryo-EM buffer pH 8
cryo-EM vitrification conditions Cryogen ETHANE；4 seconds before plunging
Resolution 2.40 Å

4 other PDB entries and 4 assemblies. Open the comparison page and filter oligomeric states

View Construct and Data Evidence
UniProt name COX4_PARDE
Isoform —
PDB entities 4
Chains and sequence ranges Author chain D； PDBConstruct 1–50； UniProt 1–50

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

SAXS scattering curve SAXS Profile

暂无 SAXS 图

P(r) Distance Distribution P(r) Distribution

暂无 P(r) 图
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2. Structure Basics 2. Structure Basics

Entry ID entry_id7au3
Deposition date deposition_date2020-11-02
Structure title titleCytochrome c oxidase structure in F-state
Keywords keywordsTerminal oxidase Cytochrome c oxidase aa3 oxidase, MEMBRANE PROTEIN; MEMBRANE PROTEIN
Experimental Method methodELECTRON MICROSCOPY
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3. SAXS Parameters (CRYSOL theoretical calculation) 3. SAXS Parameters (CRYSOL)

该条目暂无 SAXS 数据。

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4. P(r) Distance Distribution (GNOM inversion) 4. P(r) Analysis (GNOM)

该条目暂无 P(r) 分析数据。

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5. Crystallography and Experiment 5. Crystallography & Experiment

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6. Entities and Polymers Entities & Polymers (13)

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7. Fold Classification (SCOP + CATH) 1 domains

CATH v4.4 (1 domains)

Domain ID domain_id7au3A01
Class class1 — Mainly Alpha
Architecture architecture20 — Up-down Bundle
Topology topology210 — Cytochrome C Oxidase; Chain A
Homologous superfamily homologous superfamily10 — Cytochrome c oxidase-like, subunit I domain
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8. Citations (1)

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9. Files and Curves (0)