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7b8s

Fusidic acid bound structure of bacterial efflux pump.

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Multidrug efflux pump subunit AcrB,Multidrug efflux pump subunit AcrB

Escherichia coli (strain K12)

UniProt P31224

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 6 DARPin × 3 FUSIDIC ACID × 1 water × 6 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
9fdp 9fdq

2 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers
1iwg 1oy6 1oy8 1oy9 1oyd 1oye 1t9t 1t9u 1t9v 1t9w 1t9x 1t9y

63 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
2j8s 2rdd 3noc 3nog 4c48 4cdi 4dx5 4dx6 4dx7 4u8v 4u8y 4u95

60 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name ACRB_ECOLI
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 2–292； UniProt 39–329 Author chain A； PDBConstruct 302–610； UniProt 561–869 Author chain B； PDBConstruct 2–292； UniProt 39–329 Author chain B； PDBConstruct 302–610； UniProt 561–869 Author chain C； PDBConstruct 2–292； UniProt 39–329 Author chain C； PDBConstruct 302–610； UniProt 561–869

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7b8s
Deposition date deposition_date2020-12-13
Structure title titleFusidic acid bound structure of bacterial efflux pump.
Keywords keywordsRND transporter, multidrug resistance, efflux pump, antibiotics, TRANSPORT PROTEIN; TRANSPORT PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7b8s__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7b8s__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7b8s__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）40.07 Å
Rg (electron density)39.49 Å
Total Rg39.90 Å
Atom count16922
Residues2219
Excluded volume300220 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7b8s__assembly_1__model_1 hexameric （6） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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7. Citations (1)