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7d3d

Crystal structure of SPOP bound with a peptide

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Speckle-type POZ protein

Homo sapiens

UniProt O43791

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 2 GLU-VAL-SER-ILE-ILE-GLN-GLY-ALA-ASP-SER-THR-THR × 1 GLYCEROL × 1 water × 2 Consistent with protein count
2 Protein heterocomplex Heteromer Protein 2 GLU-VAL-SER-ILE-ILE-GLN-GLY-ALA-ASP-SER-THR-THR × 1 water × 2 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2cr2 7lip 7liq

3 assemblies

Homodimer
3htm 3htm 4hs2 4j8z 4j8z

5 assemblies

Homotetramer

None

Other homooligomers
8dws 8dwt 8dwu 8dwv 9out 9ouu 9ouw

7 assemblies

Heteromeric or nucleic-acid complex
3hqi 3hql 3hql 3hqm 3hqm 3hsv 3hu6 3ivb 3ivq 3ivq 3ivv 4eoz

39 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name SPOP_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–139； UniProt 28–166 Author chain B； PDBConstruct 1–139； UniProt 28–166

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7d3d
Deposition date deposition_date2020-09-18
Structure title titleCrystal structure of SPOP bound with a peptide
Keywords keywordsccRCC, E3 ligase adaptor SPOP, ubiquitination, SBC motif(F-pS-S/T-S/T;F is nonpolar, p is polar), PROTEIN BINDING; PROTEIN BINDING
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7d3d__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7d3d__assembly_1__model_1 | I(q)

10-2 10-1 105 106 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7d3d__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）16.51 Å
Rg (electron density)15.08 Å
Total Rg16.28 Å
Atom count1214
Residues151
Excluded volume21732 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7d3d__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 7d3d__assembly_2__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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6. Fold Classification (SCOP + CATH) 2 domains

SCOP 2.08 (2 domains)

Domain ID domain_idd7d3da_
Class classb — All beta proteins
Fold Fold foldb.8 — TRAF domain-like
Superfamily Superfamily superfamilyb.8.1 — TRAF domain-like
Family Family familyb.8.1.1 — MATH domain
Domain ID domain_idd7d3db_
Class classb — All beta proteins
Fold Fold foldb.8 — TRAF domain-like
Superfamily Superfamily superfamilyb.8.1 — TRAF domain-like
Family Family familyb.8.1.1 — MATH domain
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7. Citations (1)