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7d3v

Non-specific and specific interactions work cooperatively to promote cytidine deamination catalyzed by APOBEC3A

Method: SOLUTION NMR
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1. Protein Identity and Related Structures Protein Identity & Related Structures

DNA dC->dU-editing enzyme APOBEC-3A

Homo sapiens

UniProt P31941

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Homooligomer Protein 2 DNA 2 ;DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*TP*T)-3') ; × 2 ZINC ION × 2 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer
2m65

1 assemblies

Homodimer
4xxo

1 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
5keg 5sww 5sww 5sww 5sww 7d3v 7d3w 7d3x 8fii 8fii 8fij 8fij

18 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name ABC3A_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–199； UniProt 1–199 Author chain B； PDBConstruct 1–199； UniProt 1–199

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7d3v
Deposition date deposition_date2020-09-21
Structure title titleNon-specific and specific interactions work cooperatively to promote cytidine deamination catalyzed by APOBEC3A
Keywords keywordsDNA BINDING PROTEIN-DNA COMPLEX; DNA BINDING PROTEIN/DNA
Experimental Method methodSOLUTION NMR
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7d3v__assembly_1__model_2

Assembly 1 · Model 2 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7d3v__assembly_1__model_2 | I(q)

10-2 10-1 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7d3v__assembly_1__model_2 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）25.13 Å
Rg (electron density)24.16 Å
Total Rg25.01 Å
Atom count6978
Residues418
Excluded volume62995 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7d3v__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 2 7d3v__assembly_1__model_2 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 3 7d3v__assembly_1__model_3 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 4 7d3v__assembly_1__model_4 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 5 7d3v__assembly_1__model_5 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 6 7d3v__assembly_1__model_6 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 7 7d3v__assembly_1__model_7 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 8 7d3v__assembly_1__model_8 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 9 7d3v__assembly_1__model_9 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 10 7d3v__assembly_1__model_10 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 11 7d3v__assembly_1__model_11 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 12 7d3v__assembly_1__model_12 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 13 7d3v__assembly_1__model_13 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 14 7d3v__assembly_1__model_14 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 15 7d3v__assembly_1__model_15 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 16 7d3v__assembly_1__model_16 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 17 7d3v__assembly_1__model_17 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 18 7d3v__assembly_1__model_18 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 19 7d3v__assembly_1__model_19 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
1 20 7d3v__assembly_1__model_20 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (3)

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7. Citations (1)