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8fii

Wild type APOBEC3A in complex with TT(FdZ)-hairpin inhibitor (crystal form 1)

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

DNA dC->dU-editing enzyme APOBEC-3A

Homo sapiens

UniProt P31941

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–DNA Monomer Protein 1 DNA 1 ;DNA (5'-D(P*GP*CP*GP*CP*TP*TP*(UFP)P*GP*CP*GP*C)-3') ; × 1 PHOSPHATE ION × 3 ZINC ION × 1 Consistent with all polymers
2 Protein–DNA Monomer Protein 1 DNA 1 ;DNA (5'-D(P*GP*CP*GP*CP*TP*TP*(UFP)P*GP*CP*GP*C)-3') ; × 1 PHOSPHATE ION × 4 ZINC ION × 1 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer
2m65

1 assemblies

Homodimer
4xxo

1 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
5keg 5sww 5sww 5sww 5sww 7d3v 7d3w 7d3x 8fii 8fii 8fij 8fij

18 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name ABC3A_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–199； UniProt 1–199 Author chain B； PDBConstruct 1–199； UniProt 1–199

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8fii
Deposition date deposition_date2022-12-16
Structure title titleWild type APOBEC3A in complex with TT(FdZ)-hairpin inhibitor (crystal form 1)
Keywords keywordsAPOBEC, APOBEC3A, A3A, cancer, DNA, cytidine deaminase, hairpin DNA inhibitor, DNA BINDING PROTEIN; DNA BINDING PROTEIN
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8fii__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8fii__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8fii__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）18.84 Å
Rg (electron density)17.27 Å
Total Rg18.27 Å
Atom count1675
Residues188
Excluded volume28633 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8fii__assembly_1__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 8fii__assembly_2__model_1 dimeric （2） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (4)

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7. Citations (1)