7dpz

Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Virion protein 1

OrganismNot specified

UniProt W8GTF7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 300 VP2 × 60 (A0A2S0RQC2) VP3 × 60 (L7UV52) Capsid protein VP4 × 60 (A0A2S1FMR1) Coxsackievirus and adenovirus receptor × 60 (P78310) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 5 VP2 × 1 (A0A2S0RQC2) VP3 × 1 (L7UV52) Capsid protein VP4 × 1 (A0A2S1FMR1) Coxsackievirus and adenovirus receptor × 1 (P78310) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 25 VP2 × 5 (A0A2S0RQC2) VP3 × 5 (L7UV52) Capsid protein VP4 × 5 (A0A2S1FMR1) Coxsackievirus and adenovirus receptor × 5 (P78310) Consistent with protein count
4 Protein heterocomplex Heteromer Protein 30 VP2 × 6 (A0A2S0RQC2) VP3 × 6 (L7UV52) Capsid protein VP4 × 6 (A0A2S1FMR1) Coxsackievirus and adenovirus receptor × 6 (P78310) Consistent with protein count
5 Protein heterocomplex Heteromer Protein 5 VP2 × 1 (A0A2S0RQC2) VP3 × 1 (L7UV52) Capsid protein VP4 × 1 (A0A2S1FMR1) Coxsackievirus and adenovirus receptor × 1 (P78310) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name W8GTF7_9ENTO
Isoform —
PDB entities 1
Chains and sequence ranges Author chain 1; PDBConstruct 1–278; UniProt 1–278

VP2

OrganismNot specified

UniProt A0A2S0RQC2

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 300 Virion protein 1 × 60 (W8GTF7) VP3 × 60 (L7UV52) Capsid protein VP4 × 60 (A0A2S1FMR1) Coxsackievirus and adenovirus receptor × 60 (P78310) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 5 Virion protein 1 × 1 (W8GTF7) VP3 × 1 (L7UV52) Capsid protein VP4 × 1 (A0A2S1FMR1) Coxsackievirus and adenovirus receptor × 1 (P78310) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 25 Virion protein 1 × 5 (W8GTF7) VP3 × 5 (L7UV52) Capsid protein VP4 × 5 (A0A2S1FMR1) Coxsackievirus and adenovirus receptor × 5 (P78310) Consistent with protein count
4 Protein heterocomplex Heteromer Protein 30 Virion protein 1 × 6 (W8GTF7) VP3 × 6 (L7UV52) Capsid protein VP4 × 6 (A0A2S1FMR1) Coxsackievirus and adenovirus receptor × 6 (P78310) Consistent with protein count
5 Protein heterocomplex Heteromer Protein 5 Virion protein 1 × 1 (W8GTF7) VP3 × 1 (L7UV52) Capsid protein VP4 × 1 (A0A2S1FMR1) Coxsackievirus and adenovirus receptor × 1 (P78310) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name A0A2S0RQC2_9ENTO
Isoform —
PDB entities 2
Chains and sequence ranges Author chain 2; PDBConstruct 1–263; UniProt 70–332

VP3

OrganismNot specified

UniProt L7UV52

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 300 Virion protein 1 × 60 (W8GTF7) VP2 × 60 (A0A2S0RQC2) Capsid protein VP4 × 60 (A0A2S1FMR1) Coxsackievirus and adenovirus receptor × 60 (P78310) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 5 Virion protein 1 × 1 (W8GTF7) VP2 × 1 (A0A2S0RQC2) Capsid protein VP4 × 1 (A0A2S1FMR1) Coxsackievirus and adenovirus receptor × 1 (P78310) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 25 Virion protein 1 × 5 (W8GTF7) VP2 × 5 (A0A2S0RQC2) Capsid protein VP4 × 5 (A0A2S1FMR1) Coxsackievirus and adenovirus receptor × 5 (P78310) Consistent with protein count
4 Protein heterocomplex Heteromer Protein 30 Virion protein 1 × 6 (W8GTF7) VP2 × 6 (A0A2S0RQC2) Capsid protein VP4 × 6 (A0A2S1FMR1) Coxsackievirus and adenovirus receptor × 6 (P78310) Consistent with protein count
5 Protein heterocomplex Heteromer Protein 5 Virion protein 1 × 1 (W8GTF7) VP2 × 1 (A0A2S0RQC2) Capsid protein VP4 × 1 (A0A2S1FMR1) Coxsackievirus and adenovirus receptor × 1 (P78310) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name L7UV52_9ENTO
Isoform —
PDB entities 3
Chains and sequence ranges Author chain 3; PDBConstruct 1–238; UniProt 333–570

Capsid protein VP4

OrganismNot specified

UniProt A0A2S1FMR1

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 300 Virion protein 1 × 60 (W8GTF7) VP2 × 60 (A0A2S0RQC2) VP3 × 60 (L7UV52) Coxsackievirus and adenovirus receptor × 60 (P78310) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 5 Virion protein 1 × 1 (W8GTF7) VP2 × 1 (A0A2S0RQC2) VP3 × 1 (L7UV52) Coxsackievirus and adenovirus receptor × 1 (P78310) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 25 Virion protein 1 × 5 (W8GTF7) VP2 × 5 (A0A2S0RQC2) VP3 × 5 (L7UV52) Coxsackievirus and adenovirus receptor × 5 (P78310) Consistent with protein count
4 Protein heterocomplex Heteromer Protein 30 Virion protein 1 × 6 (W8GTF7) VP2 × 6 (A0A2S0RQC2) VP3 × 6 (L7UV52) Coxsackievirus and adenovirus receptor × 6 (P78310) Consistent with protein count
5 Protein heterocomplex Heteromer Protein 5 Virion protein 1 × 1 (W8GTF7) VP2 × 1 (A0A2S0RQC2) VP3 × 1 (L7UV52) Coxsackievirus and adenovirus receptor × 1 (P78310) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name A0A2S1FMR1_9ENTO
Isoform —
PDB entities 4
Chains and sequence ranges Author chain 4; PDBConstruct 1–69; UniProt 1–69

Coxsackievirus and adenovirus receptor

OrganismNot specified

UniProt P78310

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 300 Virion protein 1 × 60 (W8GTF7) VP2 × 60 (A0A2S0RQC2) VP3 × 60 (L7UV52) Capsid protein VP4 × 60 (A0A2S1FMR1) Consistent with protein count
2 Protein heterocomplex Heteromer Protein 5 Virion protein 1 × 1 (W8GTF7) VP2 × 1 (A0A2S0RQC2) VP3 × 1 (L7UV52) Capsid protein VP4 × 1 (A0A2S1FMR1) Consistent with protein count
3 Protein heterocomplex Heteromer Protein 25 Virion protein 1 × 5 (W8GTF7) VP2 × 5 (A0A2S0RQC2) VP3 × 5 (L7UV52) Capsid protein VP4 × 5 (A0A2S1FMR1) Consistent with protein count
4 Protein heterocomplex Heteromer Protein 30 Virion protein 1 × 6 (W8GTF7) VP2 × 6 (A0A2S0RQC2) VP3 × 6 (L7UV52) Capsid protein VP4 × 6 (A0A2S1FMR1) Consistent with protein count
5 Protein heterocomplex Heteromer Protein 5 Virion protein 1 × 1 (W8GTF7) VP2 × 1 (A0A2S0RQC2) VP3 × 1 (L7UV52) Capsid protein VP4 × 1 (A0A2S1FMR1) Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence
UniProt name CXAR_HUMAN
Isoform —
PDB entities 5
Chains and sequence ranges Author chain K; PDBConstruct 1–121; UniProt 20–140

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7dpz
Deposition date deposition_date2020-12-22
Structure title titleCryo-EM structure of Coxsackievirus B1 virion in complex with CAR
Keywords keywordsCoxsackievirus B1, CAR, Cryo-EM, VIRUS; VIRUS
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7dpz__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7dpz__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 1010 1011 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7dpz__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg(Guinier)0.00 Å
Rg (electron density)138.20 Å
Total Rg138.20 Å
Atom count430740
Residues55020
Excluded volume7649700 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7dpz__assembly_1__model_1 300-meric (300) Success 4.1.3-1-20251215 (887e7ef) View Download
2 1 7dpz__assembly_2__model_1 pentameric (5) Excluded — —
Exclusion reason: Auxiliary symmetry representation; not a complete or representative biological assembly.
3 1 7dpz__assembly_3__model_1 25-meric (25) Excluded — —
Exclusion reason: Auxiliary symmetry representation; not a complete or representative biological assembly.
4 1 7dpz__assembly_4__model_1 30-meric (30) Excluded — —
Exclusion reason: Auxiliary symmetry representation; not a complete or representative biological assembly.
5 1 7dpz__assembly_5__model_1 pentameric (5) Excluded — —
Exclusion reason: Auxiliary symmetry representation; not a complete or representative biological assembly.
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

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6. Fold Classification (SCOP + CATH) 1 domains

CATH v4.4 (1 domains)

Domain ID domain_id7dpz201
Class class2 — Mainly Beta
Architecture architecture60 — Sandwich
Topology topology120 — Jelly Rolls
Homologous superfamily homologous superfamily20 —
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7. Citations (1)