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7kuf

Transcription activation subcomplex with WhiB7 bound to SigmaAr4-RNAP Beta flap tip chimera and DNA

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Probable transcriptional regulator WhiB7

Mycobacterium tuberculosis

UniProt Q6MX01

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 2 DNA 2 RNA polymerase sigma factor, DNA-directed RNA polymerase subunit beta chimera × 1 （A0A654TMB9,A1KGE7） ;DNA (5'-D(*CP*AP*GP*AP*AP*AP*AP*TP*CP*GP*GP*TP*TP*GP*TP*GP*GP*T)-3') ; × 1 ;DNA (5'-D(*GP*AP*CP*CP*AP*CP*AP*AP*CP*CP*GP*AP*TP*TP*TP*TP*CP*T)-3') ; × 1 IRON/SULFUR CLUSTER × 1 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
7kif 7kim 7kuf 7kug 7kug

5 assemblies

View Construct and Data Evidence
UniProt name WHB7A_MYCTU
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–92； UniProt 1–92

RNA polymerase sigma factor, DNA-directed RNA polymerase subunit beta chimera

Mycobacterium tuberculosis

UniProt A0A654TMB9

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 2 DNA 2 Probable transcriptional regulator WhiB7 × 1 （Q6MX01） ;DNA (5'-D(*CP*AP*GP*AP*AP*AP*AP*TP*CP*GP*GP*TP*TP*GP*TP*GP*GP*T)-3') ; × 1 ;DNA (5'-D(*GP*AP*CP*CP*AP*CP*AP*AP*CP*CP*GP*AP*TP*TP*TP*TP*CP*T)-3') ; × 1 IRON/SULFUR CLUSTER × 1 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
7kuf 7kug 7kug 8cyf

4 assemblies

View Construct and Data Evidence
UniProt name A0A654TMB9_MYCTX
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 9–91； UniProt 295–377

RNA polymerase sigma factor, DNA-directed RNA polymerase subunit beta chimera

Mycobacterium tuberculosis

UniProt A1KGE7

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Insufficient information Heteromer Protein 2 DNA 2 Probable transcriptional regulator WhiB7 × 1 （Q6MX01） ;DNA (5'-D(*CP*AP*GP*AP*AP*AP*AP*TP*CP*GP*GP*TP*TP*GP*TP*GP*GP*T)-3') ; × 1 ;DNA (5'-D(*GP*AP*CP*CP*AP*CP*AP*AP*CP*CP*GP*AP*TP*TP*TP*TP*CP*T)-3') ; × 1 IRON/SULFUR CLUSTER × 1 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
7kuf 7kug 7kug 8cyf

4 assemblies

View Construct and Data Evidence
UniProt name RPOB_MYCBP
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 98–112； UniProt 815–829

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id7kuf
Deposition date deposition_date2020-11-24
Structure title titleTranscription activation subcomplex with WhiB7 bound to SigmaAr4-RNAP Beta flap tip chimera and DNA
Keywords keywordsRedox-sensitive, Iron-sulfur cluster, transcription, activator; TRANSCRIPTION
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

7kuf__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

7kuf__assembly_1__model_1 | I(q)

10-2 10-1 105 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

7kuf__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）21.30 Å
Rg (electron density)20.40 Å
Total Rg21.15 Å
Atom count1987
Residues194
Excluded volume33009 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 7kuf__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

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7. Citations (1)