Severe acute respiratory syndrome coronavirus 2
| Assembly | 物理组成 | 蛋白状态 | 分子拷贝数 | 共同组分 | 数据核对 |
|---|---|---|---|---|---|
| 1 | 蛋白同源多聚体 | 同源多聚体 | 蛋白 2 | 5-(3-{3-chloro-5-[(3-fluorophenyl)methoxy]phenyl}-2-oxo-2H-[1,3'-bipyridin]-5-yl)pyrimidine-2,4(1H,3H)-dione × 1 water × 2 | 与蛋白数一致 |
| UniProt名称 | R1AB_SARS2 |
| Isoform | — |
| PDB实体 | 1 |
| 链与序列区间 | 作者链 A； PDB构建体 1–306； UniProt 3264–3569 作者链 B； PDB构建体 1–306； UniProt 3264–3569 |
页面优先展示蛋白身份、当前 assembly、共同组分、聚集状态和跨 PDB 结构链接。 链映射与序列区间收在“数据证据”中；数据库内部编号、导入时间和 assembly 操作表达式仅用于维护，因此不在读者页面展示。
| 条目编号 entry_id | 7m8o |
| 沉积日期 deposition_date | 2021-03-30 |
| 结构标题 title | CRYSTAL STRUCTURE OF THE SARS-COV-2(2019-NCOV) MAIN PROTEASE IN COMPLEX WITH COMPOUND 19 |
| 关键词 keywords | VIRAL PROTEIN, Hydrolase; VIRAL PROTEIN, Hydrolase |
| 实验方法 method | X-RAY DIFFRACTION |
页面只读取最新 assembly 计算结果。每一条曲线都对应明确的 PDB、official biological assembly 和 coordinate model。
Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)
| Rg（Guinier） | 26.36 Å |
| Rg（电子密度） | 25.36 Å |
| 总 Rg | 26.22 Å |
| 原子数 | 4576 |
| 残基数 | 590 |
| 排除体积 | 81064 ų |
| 最大 q | 0.500 Å⁻¹ |
| 结构域编号 domain_id | d7m8oa_ |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.47 — Trypsin-like serine proteases |
| 超家族 Superfamily superfamily | b.47.1 — Trypsin-like serine proteases |
| 家族 Family family | b.47.1.4 — Viral cysteine protease of trypsin fold |
| 结构域编号 domain_id | d7m8ob_ |
| 类 Class class | b — All beta proteins |
| 折叠类型 Fold fold | b.47 — Trypsin-like serine proteases |
| 超家族 Superfamily superfamily | b.47.1 — Trypsin-like serine proteases |
| 家族 Family family | b.47.1.4 — Viral cysteine protease of trypsin fold |
| 结构域编号 domain_id | 7m8oA01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 10 — Thrombin, subunit H |
| 同源超家族 H-superfamily homologous superfamily | 10 — Trypsin-like serine proteases |
| 结构域编号 domain_id | 7m8oA02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 1840 — main proteinase (3clpro) structure, domain 3 |
| 同源超家族 H-superfamily homologous superfamily | 10 — main proteinase (3clpro) structure, domain 3 |
| 结构域编号 domain_id | 7m8oB01 |
| 类 Class class | 2 — Mainly Beta |
| 架构 Architecture architecture | 40 — Beta Barrel |
| 拓扑 Topology topology | 10 — Thrombin, subunit H |
| 同源超家族 H-superfamily homologous superfamily | 10 — Trypsin-like serine proteases |
| 结构域编号 domain_id | 7m8oB02 |
| 类 Class class | 1 — Mainly Alpha |
| 架构 Architecture architecture | 10 — Orthogonal Bundle |
| 拓扑 Topology topology | 1840 — main proteinase (3clpro) structure, domain 3 |
| 同源超家族 H-superfamily homologous superfamily | 10 — main proteinase (3clpro) structure, domain 3 |