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8cj2

Urea-based foldamer inhibitor c3u_5 chimera in complex with ASF1 histone chaperone

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Histone chaperone ASF1A

Homo sapiens

UniProt Q9Y294

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 8 c3u_5 chimera inhibitor of histone chaperone ASF1 × 4 GLYCEROL × 14 SULFATE ION × 1 water × 7 Consistent with protein count

Other States of the Same Protein in the Database

Monomer
1tey 7lny 7lny 7lny 7lny 7lny 7lny 7lny

8 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
2i32 2i32 3aad 5c3i 5c3i 5c3i 5c3i 5c3i 5c3i 6f0f 6f0g 6f0g

37 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name ASF1A_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–156； UniProt 1–156 Author chain B； PDBConstruct 1–156； UniProt 1–156 Author chain C； PDBConstruct 1–156； UniProt 1–156 Author chain D； PDBConstruct 1–156； UniProt 1–156

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8cj2
Deposition date deposition_date2023-02-11
Structure title titleUrea-based foldamer inhibitor c3u_5 chimera in complex with ASF1 histone chaperone
Keywords keywordsInhibitor, ASF1, Histone, protein-protein interaction, CHAPERONE; CHAPERONE
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8cj2__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8cj2__assembly_1__model_1 | I(q)

10-2 10-1 106 107 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8cj2__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）31.11 Å
Rg (electron density)30.32 Å
Total Rg30.96 Å
Atom count5428
Residues634
Excluded volume96676 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8cj2__assembly_1__model_1 octameric （8） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (5)

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7. Citations (1)