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8cl1

HIV-1 mature capsid hexamer from CA-IP6 CLPs, bound to CPSF6 peptide.

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Gag polyprotein

Human immunodeficiency virus 1

UniProt B6DRA0

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 12 Cleavage and polyadenylation specificity factor subunit 6 × 6 （Q16630） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
7urt 7urt 8eep 8eep 8eet 8eet

6 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers
5mcx 5mcy 5up4 5w4o 5w4p 5w4q 6axr 6axs 6axt 6axv 6axw 6axx

88 assemblies; showing the first 12

Heteromeric or nucleic-acid complex
6ay9 6obh 6pu1 7n9u 7n9v 7n9x 8cky 8cl0 8cl1 8cl3

10 assemblies

View Construct and Data Evidence
UniProt name B6DRA0_9HIV1
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 2–232； UniProt 133–363

Cleavage and polyadenylation specificity factor subunit 6

OrganismNot specified

UniProt Q16630

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 12 Gag polyprotein × 6 （B6DRA0） Consistent with protein count

Other States of the Same Protein in the Database

Monomer

None

Homodimer

None

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3p5t 3p5t 3p5t 3p6y 3p6y 3p6y 3p6y 3q2s 3q2t 4b4n 4u0a 4u0b

25 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name CPSF6_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain B； PDBConstruct 1–15； UniProt 276–290

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8cl1
Deposition date deposition_date2023-02-16
Structure title titleHIV-1 mature capsid hexamer from CA-IP6 CLPs, bound to CPSF6 peptide.
Keywords keywordsCapsid, Hexamer, HIV-1, Mature, CPSF6, VIRUS LIKE PARTICLE; VIRUS LIKE PARTICLE
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8cl1__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8cl1__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8cl1__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）36.53 Å
Rg (electron density)35.64 Å
Total Rg36.15 Å
Atom count10494
Residues1362
Excluded volume186950 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8cl1__assembly_1__model_1 dodecameric （12） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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6. Fold Classification (SCOP + CATH) 1 domains

CATH v4.4 (1 domains)

Domain ID domain_id8cl1A01
Class class1 — Mainly Alpha
Architecture architecture10 — Orthogonal Bundle
Topology topology375 — Human Immunodeficiency Virus Type 1 Capsid Protein
Homologous superfamily homologous superfamily10 — Human Immunodeficiency Virus Type 1 Capsid Protein
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7. Citations (1)