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8czo

Cryo-EM structure of BCL10 CARD - MALT1 DD filament

Method: ELECTRON MICROSCOPY
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1. Protein Identity and Related Structures Protein Identity & Related Structures

Mucosa-associated lymphoid tissue lymphoma translocation protein 1

Homo sapiens

UniProt Q9UDY8

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 44 B-cell lymphoma/leukemia 10 × 22 （O95999） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2g7r 2g7r 3bfo 3bfo 3bfo 3bfo 3v55 6h4a 6yn8 6yn9 7ak1 9bp2

16 assemblies; showing the first 12

Homodimer
4i1r 6f7i 7a41 7ak0 7pav 7paw 8j5i 9mkd

8 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3uo8 3uo8 3uoa 3v4o 4i1p 4i1p 4i1p 6gk2 8czo 8v4x 8v4x 8v4x

13 assemblies; showing the first 12

View Construct and Data Evidence
UniProt name MALT1_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain a； PDBConstruct 1–94； UniProt 29–122 Author chain b； PDBConstruct 1–94； UniProt 29–122 Author chain c； PDBConstruct 1–94； UniProt 29–122 Author chain d； PDBConstruct 1–94； UniProt 29–122 Author chain e； PDBConstruct 1–94； UniProt 29–122 Author chain f； PDBConstruct 1–94； UniProt 29–122 Author chain g； PDBConstruct 1–94； UniProt 29–122 Author chain h； PDBConstruct 1–94； UniProt 29–122 Author chain i； PDBConstruct 1–94； UniProt 29–122 Author chain j； PDBConstruct 1–94； UniProt 29–122 Author chain k； PDBConstruct 1–94； UniProt 29–122 Author chain l； PDBConstruct 1–94； UniProt 29–122 Author chain m； PDBConstruct 1–94； UniProt 29–122 Author chain n； PDBConstruct 1–94； UniProt 29–122 Author chain o； PDBConstruct 1–94； UniProt 29–122 Author chain p； PDBConstruct 1–94； UniProt 29–122 Author chain q； PDBConstruct 1–94； UniProt 29–122 Author chain r； PDBConstruct 1–94； UniProt 29–122 Author chain s； PDBConstruct 1–94； UniProt 29–122 Author chain t； PDBConstruct 1–94； UniProt 29–122 Author chain u； PDBConstruct 1–94； UniProt 29–122 Author chain v； PDBConstruct 1–94； UniProt 29–122

B-cell lymphoma/leukemia 10

Homo sapiens

UniProt O95999

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein heterocomplex Heteromer Protein 44 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 × 22 （Q9UDY8） Consistent with protein count

Other States of the Same Protein in the Database

Monomer
2mb9

1 assemblies

Homodimer

None

Homotetramer

None

Other homooligomers
6bze 8czd

2 assemblies

Heteromeric or nucleic-acid complex
6gk2 8czo

2 assemblies

View Construct and Data Evidence
UniProt name BCL10_HUMAN
Isoform —
PDB entities 2
Chains and sequence ranges Author chain A； PDBConstruct 1–106； UniProt 10–115 Author chain B； PDBConstruct 1–106； UniProt 10–115 Author chain C； PDBConstruct 1–106； UniProt 10–115 Author chain D； PDBConstruct 1–106； UniProt 10–115 Author chain E； PDBConstruct 1–106； UniProt 10–115 Author chain F； PDBConstruct 1–106； UniProt 10–115 Author chain G； PDBConstruct 1–106； UniProt 10–115 Author chain H； PDBConstruct 1–106； UniProt 10–115 Author chain I； PDBConstruct 1–106； UniProt 10–115 Author chain J； PDBConstruct 1–106； UniProt 10–115 Author chain K； PDBConstruct 1–106； UniProt 10–115 Author chain L； PDBConstruct 1–106； UniProt 10–115 Author chain M； PDBConstruct 1–106； UniProt 10–115 Author chain N； PDBConstruct 1–106； UniProt 10–115 Author chain O； PDBConstruct 1–106； UniProt 10–115 Author chain P； PDBConstruct 1–106； UniProt 10–115 Author chain Q； PDBConstruct 1–106； UniProt 10–115 Author chain R； PDBConstruct 1–106； UniProt 10–115 Author chain S； PDBConstruct 1–106； UniProt 10–115 Author chain T； PDBConstruct 1–106； UniProt 10–115 Author chain U； PDBConstruct 1–106； UniProt 10–115 Author chain V； PDBConstruct 1–106； UniProt 10–115

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8czo
Deposition date deposition_date2022-05-25
Structure title titleCryo-EM structure of BCL10 CARD - MALT1 DD filament
Keywords keywordsfilament, CBM complex, IMMUNE SYSTEM; IMMUNE SYSTEM
Experimental Method methodELECTRON MICROSCOPY
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8czo__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8czo__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 109 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8czo__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）54.52 Å
Rg (electron density)54.23 Å
Total Rg54.58 Å
Atom count34518
Residues4268
Excluded volume618780 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8czo__assembly_1__model_1 44-meric （44） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (2)

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7. Citations (1)