8ro0

Structure of the C. elegans Intron Lariat Spliceosome primed for disassembly (ILS')

Method: ELECTRON MICROSCOPY

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1. Protein Identity and Related Structures Protein Identity & Related Structures

Pre-mRNA-splicing factor 8 homolog

OrganismNot specified

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	PRP8_CAEEL
Isoform	—
PDB entities	4
Chains and sequence ranges	Author chain A； PDBConstruct 1–2329； UniProt 1–2329

U5 small nuclear ribonucleoprotein 200 kDa helicase

OrganismNot specified

UniProt Q9U2G0

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	U520_CAEEL
Isoform	—
PDB entities	5
Chains and sequence ranges	Author chain B； PDBConstruct 1–2145； UniProt 1–2145

Tr-type G domain-containing protein

OrganismNot specified

UniProt Q23463

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q23463_CAEEL
Isoform	—
PDB entities	6
Chains and sequence ranges	Author chain C； PDBConstruct 1–974； UniProt 1–974

Protein isy-1

OrganismNot specified

UniProt Q20716

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	ISY1_CAEEL
Isoform	—
PDB entities	7
Chains and sequence ranges	Author chain D； PDBConstruct 1–267； UniProt 1–267

WD_REPEATS_REGION domain-containing protein

OrganismNot specified

UniProt Q19211

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q19211_CAEEL
Isoform	—
PDB entities	8
Chains and sequence ranges	Author chain E； PDBConstruct 1–331； UniProt 1–331

Pre-mRNA-splicing factor SYF1

OrganismNot specified

UniProt P91175

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	P91175_CAEEL
Isoform	—
PDB entities	9
Chains and sequence ranges	Author chain I； PDBConstruct 1–855； UniProt 1–855

TPR_REGION domain-containing protein

OrganismNot specified

UniProt O16376

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	O16376_CAEEL
Isoform	—
PDB entities	10
Chains and sequence ranges	Author chain J； PDBConstruct 1–744； UniProt 1–744

Pre-mRNA-splicing factor SPF27

OrganismNot specified

UniProt Q22417

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q22417_CAEEL
Isoform	—
PDB entities	11
Chains and sequence ranges	Author chain K； PDBConstruct 1–238； UniProt 1–238

Cell division cycle 5-like protein

OrganismNot specified

UniProt G5EFC4

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	G5EFC4_CAEEL
Isoform	—
PDB entities	12
Chains and sequence ranges	Author chain L； PDBConstruct 1–755； UniProt 1–755

Pre-mRNA-splicing factor syf-2

OrganismNot specified

UniProt Q09385

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	SYF2_CAEEL
Isoform	—
PDB entities	13
Chains and sequence ranges	Author chain M； PDBConstruct 1–234； UniProt 1–234

Protein BUD31 homolog

OrganismNot specified

UniProt P34313

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	BUD31_CAEEL
Isoform	—
PDB entities	14
Chains and sequence ranges	Author chain N； PDBConstruct 1–147； UniProt 1–147

Pre-mRNA-splicing factor RBM22

OrganismNot specified

UniProt Q22412

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q22412_CAEEL
Isoform	—
PDB entities	15
Chains and sequence ranges	Author chain O； PDBConstruct 1–408； UniProt 1–408

Spliceosome-associated protein CWC15 homolog

OrganismNot specified

UniProt O45766

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	CWC15_CAEEL
Isoform	—
PDB entities	16
Chains and sequence ranges	Author chain P； PDBConstruct 1–230； UniProt 1–230

GCF C-terminal domain-containing protein

OrganismNot specified

UniProt G5ECH1

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	G5ECH1_CAEEL
Isoform	—
PDB entities	17
Chains and sequence ranges	Author chain PX； PDBConstruct 1–809； UniProt 1–809

Intron-binding protein aquarius

OrganismNot specified

UniProt Q9U1Q7

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q9U1Q7_CAEEL
Isoform	—
PDB entities	18
Chains and sequence ranges	Author chain Q； PDBConstruct 1–1467； UniProt 1–1467

Uncharacterized protein T27F2.1

OrganismNot specified

UniProt Q22836

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	YGH1_CAEEL
Isoform	—
PDB entities	19
Chains and sequence ranges	Author chain R； PDBConstruct 1–535； UniProt 1–535

Peptidyl-prolyl cis-trans isomerase

OrganismNot specified

UniProt Q18445

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q18445_CAEEL
Isoform	—
PDB entities	20
Chains and sequence ranges	Author chain S； PDBConstruct 1–169； UniProt 1–169

WD_REPEATS_REGION domain-containing protein

OrganismNot specified

UniProt G5EEL2

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	G5EEL2_CAEEL
Isoform	—
PDB entities	21
Chains and sequence ranges	Author chain T； PDBConstruct 1–494； UniProt 1–494

Septin and tuftelin-interacting protein 1 homolog

OrganismNot specified

UniProt Q17784

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	TFP11_CAEEL
Isoform	—
PDB entities	22
Chains and sequence ranges	Author chain TF； PDBConstruct 1–830； UniProt 1–830

WD_REPEATS_REGION domain-containing protein

OrganismNot specified

UniProt O44729

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	O44729_CAEEL
Isoform	—
PDB entities	23
Chains and sequence ranges	Author chain W； PDBConstruct 1–567； UniProt 1–567

Coiled-coil domain-containing protein 12

OrganismNot specified

UniProt Q95XJ1

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q95XJ1_CAEEL
Isoform	—
PDB entities	24
Chains and sequence ranges	Author chain Z； PDBConstruct 1–169； UniProt 1–169

Small nuclear ribonucleoprotein Sm D3

OrganismNot specified

UniProt Q17348

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	SMD3_CAEEL
Isoform	—
PDB entities	25
Chains and sequence ranges	Author chain a； PDBConstruct 1–136； UniProt 1–136 Author chain h； PDBConstruct 1–136； UniProt 1–136

Probable small nuclear ribonucleoprotein-associated protein B

OrganismNot specified

UniProt P91918

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RSMB_CAEEL
Isoform	—
PDB entities	26
Chains and sequence ranges	Author chain b； PDBConstruct 1–160； UniProt 1–160 Author chain i； PDBConstruct 1–160； UniProt 1–160

Small nuclear ribonucleoprotein Sm D1

OrganismNot specified

UniProt E3LR34

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	E3LR34_CAERE
Isoform	—
PDB entities	27
Chains and sequence ranges	Author chain c； PDBConstruct 1–127； UniProt 1–127 Author chain j； PDBConstruct 1–127； UniProt 1–127

Probable small nuclear ribonucleoprotein Sm D2

OrganismNot specified

UniProt Q18786

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	SMD2_CAEEL
Isoform	—
PDB entities	28
Chains and sequence ranges	Author chain d； PDBConstruct 1–118； UniProt 1–118 Author chain k； PDBConstruct 1–118； UniProt 1–118

Probable small nuclear ribonucleoprotein E

OrganismNot specified

UniProt Q9XTU6

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RUXE_CAEEL
Isoform	—
PDB entities	29
Chains and sequence ranges	Author chain e； PDBConstruct 1–90； UniProt 1–90 Author chain l； PDBConstruct 1–90； UniProt 1–90

Probable small nuclear ribonucleoprotein F

OrganismNot specified

UniProt P34659

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RUXF_CAEEL
Isoform	—
PDB entities	30
Chains and sequence ranges	Author chain f； PDBConstruct 1–85； UniProt 1–85 Author chain m； PDBConstruct 1–85； UniProt 1–85

Probable small nuclear ribonucleoprotein G

OrganismNot specified

UniProt Q9N4G9

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RUXG_CAEEL
Isoform	—
PDB entities	31
Chains and sequence ranges	Author chain g； PDBConstruct 1–77； UniProt 1–77 Author chain n； PDBConstruct 1–77； UniProt 1–77

;Probable U2 small nuclear ribonucleoprotein A' ;

OrganismNot specified

UniProt Q9BLB6

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	RU2A_CAEEL
Isoform	—
PDB entities	32
Chains and sequence ranges	Author chain o； PDBConstruct 1–253； UniProt 1–253

RRM domain-containing protein

OrganismNot specified

UniProt Q21323

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） Pre-mRNA-processing factor 19 × 4 （Q10051） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q21323_CAEEL
Isoform	—
PDB entities	33
Chains and sequence ranges	Author chain p； PDBConstruct 1–217； UniProt 1–217

Pre-mRNA-processing factor 19

OrganismNot specified

UniProt Q10051

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Peptidyl-prolyl cis-trans isomerase E × 1 （Q9U2S6） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	PRP19_CAEEL
Isoform	—
PDB entities	34
Chains and sequence ranges	Author chain q； PDBConstruct 1–492； UniProt 1–492 Author chain r； PDBConstruct 1–492； UniProt 1–492 Author chain s； PDBConstruct 1–492； UniProt 1–492 Author chain t； PDBConstruct 1–492； UniProt 1–492

Peptidyl-prolyl cis-trans isomerase E

OrganismNot specified

UniProt Q9U2S6

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Other combination	Heteromer	Protein 42 DNA 1 RNA 3	U2 snRNA × 1 U5 snRNA × 1 U6 snRNA × 1 Pre-mRNA-splicing factor 8 homolog × 1 （P34369） U5 small nuclear ribonucleoprotein 200 kDa helicase × 1 （Q9U2G0） Tr-type G domain-containing protein × 1 （Q23463） Protein isy-1 × 1 （Q20716） WD_REPEATS_REGION domain-containing protein × 1 （Q19211） Pre-mRNA-splicing factor SYF1 × 1 （P91175） TPR_REGION domain-containing protein × 1 （O16376） Pre-mRNA-splicing factor SPF27 × 1 （Q22417） Cell division cycle 5-like protein × 1 （G5EFC4） Pre-mRNA-splicing factor syf-2 × 1 （Q09385） Protein BUD31 homolog × 1 （P34313） Pre-mRNA-splicing factor RBM22 × 1 （Q22412） Spliceosome-associated protein CWC15 homolog × 1 （O45766） GCF C-terminal domain-containing protein × 1 （G5ECH1） Intron-binding protein aquarius × 1 （Q9U1Q7） Uncharacterized protein T27F2.1 × 1 （Q22836） Peptidyl-prolyl cis-trans isomerase × 1 （Q18445） WD_REPEATS_REGION domain-containing protein × 1 （G5EEL2） Septin and tuftelin-interacting protein 1 homolog × 1 （Q17784） WD_REPEATS_REGION domain-containing protein × 1 （O44729） Coiled-coil domain-containing protein 12 × 1 （Q95XJ1） Small nuclear ribonucleoprotein Sm D3 × 2 （Q17348） Probable small nuclear ribonucleoprotein-associated protein B × 2 （P91918） Small nuclear ribonucleoprotein Sm D1 × 2 （E3LR34） Probable small nuclear ribonucleoprotein Sm D2 × 2 （Q18786） Probable small nuclear ribonucleoprotein E × 2 （Q9XTU6） Probable small nuclear ribonucleoprotein F × 2 （P34659） Probable small nuclear ribonucleoprotein G × 2 （Q9N4G9） ;Probable U2 small nuclear ribonucleoprotein A' ; × 1 （Q9BLB6） RRM domain-containing protein × 1 （Q21323） Pre-mRNA-processing factor 19 × 4 （Q10051） Intron lariat RNA × 1 MAGNESIUM ION × 7 INOSITOL HEXAKISPHOSPHATE × 2 GUANOSINE-5'-TRIPHOSPHATE × 1 ZINC ION × 6	Consistent with all polymers

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	Q9U2S6_CAEEL
Isoform	—
PDB entities	35
Chains and sequence ranges	Author chain y； PDBConstruct 1–331； UniProt 1–331

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	8ro0
Deposition date deposition_date	2024-01-11
Structure title title	Structure of the C. elegans Intron Lariat Spliceosome primed for disassembly (ILS')
Keywords keywords	mRNA, splicing, Intorn Lariat spliceosome, ILS, pre-mRNA; SPLICING
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8ro0__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8ro0__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

8ro0__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	0.00 Å
Rg (electron density)	105.70 Å
Total Rg	105.50 Å
Atom count	121370
Residues	14602
Excluded volume	2144100 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`8ro0__assembly_1__model_1`	46-meric （46）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (40)

Entity 1 Entity 1 polymer

Description description	U2 snRNA
Molecular weight formula_weight	56554.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	2
Atom count atom_count	121370

AUCGCUUCUUCGGCUUAUUAGCUAAGAUCAAAGUGUAGUAUCUGUUCUUAUCGUAUUAACCUACGGUAUACACUCGAAUGAGUGUAAUAAAGGUUAUAUGAUUUUUGGAACCUAGGGAAGACUCGGGGCUUGCUCCGACUUCCCAAGGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNUCCCC

Entity 2 Entity 2 polymer

Description description	U5 snRNA
Molecular weight formula_weight	38680.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	5

AAACUCUGGUUCCUCUGCAUUUAACCGUGAAAAUCUUUCGCCUUUUACUAAAGAUUUCCGUGCAAAGGAGCAUACAUUGAGUAUUAUAUACAAUUUUUGGAGUCCCCUCGAAAGAGCGGGA

Entity 3 Entity 3 polymer

Description description	U6 snRNA
Molecular weight formula_weight	32483.4 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polyribonucleotide
Chain IDs strand_id	6

GUUCUUCCGAGAACAUAUACUAAAAUUGGAACAAUACAGAGAAGAUUAGCAUGGCCCCUGCGCAAGGAUGACACGCAAAUUCGUGAAGCGUUCCAAAUUUU

Entity 4 Entity 4 polymer

Description description	Pre-mRNA-splicing factor 8 homolog
Molecular weight formula_weight	272396.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	A

MANYGGHPQTEPHAIPDSILEEKSRKWKQLQGKRYSEKKKFGMSDTQKEEMPPEHVRKVIRDHGDMTSRKYRHDKRVYLGALKYMPHAVLKLLENMPMPWEQIRDVKVLYHITGAITFVNDIPRVIEPVYMAQWGTMWIMMRREKRDRRHFKRMRFPPFDDEEPPLDYADNILDVEPLEPIQMELDPEEDGAVAEWFYDHKPLATTRFVNGPTYRKWAFSIPQMSTLYRLANQLLTDLVDDNYFYLFDMKSFFTAKALNVAIPGGPKFEPLVKDLHTDEDWNEFNDINKVIIRAPIRTEYRIAFPFMYNNLISSLPVQVSWYHTPSVVFIKTEDPDLPAFYYDPLINPIVLSNLKATEENLPEGEEEDEWELPEDVRPIFEDVPLYTDNTANGLALLWAPRPFNLRSGRTRRAVDVPLVKSWYREHCPAGMPVKVRVSYQKLLKVFVLNALKHRPPKPQKRRYLFRSFKATKFFQTTTLDWVEAGLQVLRQGYNMLNLLIHRKNLNYLHLDYNFNLKPVKTLTTKERKKSRFGNAFHLCREILRLTKLVVDAHVQYRLNNVDAYQLADGLQYIFAHVGQLTGMYRYKYKLMRQVRMCKDLKHLIYYRFNTGPVGKGPGCGFWAPGWRVWLFFLRGITPLLERWLGNLLSRQFEGRHSKGVAKTVTKQRVESHFDLELRAAVMHDILDMMPDGIKQNKARVILQHLSEAWRCWKANIPWKVPGLPTPVENMILRYVKAKADWWTNSAHYNRERVRRGATVDKTVCKKNLGRLTRLYLKSEQERQHNYLKDGPYISAEEAVAIYTTTVHWLESRRFSPIPFPPLSYKHDTKLLILALERLKESYSVKNRLNQSQREELALIEQAYDNPHEALSRIKRHMLTQRAFKEVGIEFMDLYTHLIPVYDIEPLEKVTDAYLDQYLWYEADKRRLFPAWVKPGDTEPPPLLTYKWCQGLNNLQDVWETSEGECNVIMETKLEKIAEKMDLTLLNRLLRLIVDHNIADYMTSKNNVLINYKDMNHTNSFGIIRGLQFASFIVQFYGLVLDLLVLGLRRASEIAGPPQCPNEFLQFQDVATEIGHPIRLYCRYIDRVWIMFRFSADEARDLIQRYLTEHPDPNNENIVGYNNKKCWPRDARMRLMKHDVNLGRAVFWDIKNRLPRSITTVEWENSFVSVYSKDNPNMLFDMSGFECRILPKCRTANEEFVHRDGVWNLQNEVTKERTAQCFLKVDEESLSKFHNRIRQILMSSGSTTFTKIVNKWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKEIGGLGMLSMGHVLIPQSDLRWMQQTEAGGVTHFRSGMSHDEDQLIPNLYRYIQPWEAEFVDSVRVWAEYALKRQEANAQNRRLTLEDLDDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTEFKAYQILKQNPFWWTHQRHDGKLWNLNNYRTDMIQALGGVEGILEHTLFRGTYFPTWEGLFWERASGFEESMKFKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIFMHGKIPTLKISLIQIFRAHLWQKIHESVVMDLCQVFDQELDALEIQTVQKETIHPRKSYKMNSSCADVLLFAQYKWNVSRPSLMADSKDVMDNTTTQKYWLDVQLRWGDYDSHDVERYARAKFLDYTTDNMSIYPSPTGVLIAIDLAYNLYSAYGNWFPGMKPLIRQAMAKIIKANPAFYVLRERIRKGLQLYSSEPTEPYLTSQNYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLSQLAKWKTAEEVAALIRSLPVEEQPRQIIVTRKAMLDPLEVHLLDFPNIVIKGSELMLPFQAIMKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRVVLIMRGMHINPDKTKVILKPDKTTITEPHHIWPTLSDDDWIKVELALKDMILADYGKKNNVNVASLTQSEVRDIILGMEISAPSQQRQQIADIEKQTKEQSQVTATTTRTVNKHGDEIITATTSNYETASFASRTEWRVRAISSTNLHLRTQHIYVNSDDVKDTGYTYILPKNILKKFITISDLRTQIAGFMYGVSPPDNPQVKEIRCIVLVPQTGSHQQVNLPTQLPDHELLRDFEPLGWMHTQPNELPQLSPQDVTTHAKLLTDNISWDGEKTVMITCSFTPGSVSLTAYKLTPSGYEWGKANTDKGNNPKGYMPTHYEKVQMLLSDRFLGYFMVPSNGVWNYNFQGQRWSPAMKFDVCLSNPKEYYHEDHRPVHFHNFKAFDDPLGTGSADREDAFA

Entity 5 Entity 5 polymer

Description description	U5 small nuclear ribonucleoprotein 200 kDa helicase
Molecular weight formula_weight	244151.6 kDa
EC 编号 ec_number	3.6.4.13
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	B

MADELARIQQYEYRQNSNLVLSVDYNLTDRRGREEPTGEVLPITDKEMRKMKMGDRAIKGKAPVQDQKKKRKKKDDEKAQQFGRNVLVDNNELMGAYKPRTQETKQTYEVILSFILDALGDVPREVLCGAADEVLLTLKNDKFRDKEKKKEVEALLGPLTDDRIAVLINLSKKISDFSIEEENKPEGDGDIYENEGVNVQFDSDEEEDDGGMVNEIKGDSEEESEEEEGVDTDYTATLKGDGHLTEDEQKARGILHPRDIDAHWIQRSLAKYFKDPLIAQQKQTEVIGILKNAADDRDAENQLVLLLGFDQFEFIKCLRQNRLMILYCTLLRQANEKERLQIEDDMRSRPELHPILALLQETDEGSVVQVEKSKRDAEKSKKAATAANEAISAGQWQAGRKMLDLNDLTFSQGSHLMSNKRCELPDGSYRRQKKSYEEIHVPALKPRPFAEGEKLVSVSELPKWAQPAFDGYKSLNRIQSRLCDSALRSKEHLLLCAPTGAGKTNVALLTMLQEIGNHLAEDGSVKLDEFKIVYIAPMKSLVQEMVGSFSKRLAPFGITVGEMTGDAQMSKEQFMATQVIVCTPEKYDVVTRKGGERAYNQMVRLLIIDEIHLLHDDRGPVLESIVVRTIRQMEQNHDECRLVGLSATLPNYQDVATFLRVKPEHLHFFDNSYRPVPLEQQYIGVTEKKALKRFQAMNEVVYDKIMEHAGKSQVLVFVHSRKETAKTAKAIRDACLEKDTLSAFMREGSASTEILRTEAEQAKNLDLKDLLPYGFAIHHAGMNRVDRTLVEDLFADRHIQVLFSTATLAWGVNLPAHTVIIKGTQIYNPEKGRWTELGALDIMQMLGRAGRPQYDDRGEGILITNHSELQYYLSLMNQQLPVESQMVSRLTDMLNAEVVLGTVSSVSEATNWLGYTFLFVRMLKNPTLYGITHEQARADPLLEQRRADLIHTACVLLDKAGLIKYDKRSGIIQATELGRIASHFYCTYESMQTYNKLLVETCSDIDLFRIFSMSSEFKLLSVRDEEKLELQKMAEHAPIPIKENLDEASAKTNVLLQAYISQLKLEGFALQADMVFVAQSAGRLFRALFEIVLWRGWAGLAQKVLTLCKMVTQRQWGSLNPLHQFKKIPSEVVRSIDKKNYSFDRLYDLDQHQLGDLIKMPKMGKPLFKFIRQFPKLEMTTLIQPITRTTMRIELTITPDFKWDEKVHGSAEGFWIFIEDTDGEKILHHEFFLLKQKFCSDEHVVKMIVPMFDPMPPLYYVRIVSDRWIGAETVLPISFRHLILPEKYPPPTELLDLQPLPISAVTNKEFQTVFAESGFKVFNPIQTQVFRTVFESNENVIVCAPNGSGKTAIAELAVLRHFENTPEAKAVYITPMEDMATKVYADWKRRLEPAIGHTIVLLTGEQTMDLKLAQRGQLIISTPERWDNISRRWKQRKSVQNVKLFIADDLHMIGASNGAVFEVVCSRTRYISSQLESAVRVVALSSSLTNARDLGMWLGCSASATFNFMPSTRPVPLDLEIKSFNLSHNASRFAAMERPVYQAICRHAGKLEPKPALVFVPVRRQTRPVAVALLTMALADGAPKRFLRLAEHDDTFQALLADIEDESLRESVSCGVGFLHEGTAPKDVHIVQQLFESNAIQVCVVPRGMCYQIEMSAYLVVVMDTQFYNGKYHVYEDYPIADMLHMVGLANRPILDSDAKCVVMCQTSKRAYYKKFLCDPLPVESHLDHCLHDHFNAEIVTKTIENKQDAIDYLTWTLLYRRMTQNPNYYNLQGTTHRHLSDALSELVELTLKDLENSKCIAVKDEMDTVSLNLGMIASYYYISYQTIELFSMSLKEKTKTRALIEIISASSEFGNVPMRHKEDVILRQLAERLPGQLKNQKFTDPHVKVNLLIHAHLSRVKLTAELNKDTELIVLRACRLVQACVDVLSSNGWLSPAIHAMELSQMLTQAMYSNEPYLKQLPHCSAALLERAKAKEVTSVFELLELENDDRSDILQMEGAELADVARFCNHYPSIEVATELENDVVTSNDNLMLAVSLERDNDIDGLAPPVVAPLFPQKRKEEGWWLVIGDSESNALLTIKRLVINEKSSVQLDFAAPRPGHHKFKLFFISDSYLGADQEFDVAFKVEEPGRSNRKRKHEKEED

Entity 6 Entity 6 polymer

Description description	Tr-type G domain-containing protein
Molecular weight formula_weight	110612.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	C

MDSDLYDEFGNYIGPELDSDDDAGDIDDNGDDEDRSDVDEDDEPDRMEEDDAEEIPQNQVVLHEDKKYYATALEVYGEGVETLVQEEDAQPLTEPIVKPVSKKKFQAAERFLPETVYKKEYLADLMDCPHIMRNVAIAGHLHHGKTTFLDCLMEQTHPEFYRAEDADARFTDILFIEKQRGCSIKSQPVSIVAQDSRSKSYLLNIIDTPGHVNFSDEMTASYRLADGVVVMVDAHEGVMMNTERAIRHAIQERLAVTLCISKIDRLLLELKLPPADAYFKLRLIIDQVNNILSTFAEEDVPVLSPLNGNVIFSSGRYNVCFSLLSFSNIYAKQHGDSFNSKEFARRLWGDIYFEKKTRKFVKKSPSHDAPRTFVQFILEPMYKIFSQVVGDVDTCLPDVMAELGIRLSKEEQKMNVRPLIALICKRFFGDFSAFVDLVVQNIKSPLENAKTKIEQTYLGPADSQLAQEMQKCNAEGPLMVHTTKNYPVDDATQFHVFGRVMSGTLEANTDVRVLGENYSIQDEEDCRRMTVGRLFVRVASYQIEVSRVPAGCWVLIEGIDQPIVKTATIAELGYEEDVYIFRPLKFNTRSCVKLAVEPINPSELPKMLDGLRKVNKSYPLLTTRVEESGEHVLLGTGEFYMDCVMHDMRKVFSEIDIKVADPVVTFNETVIETSTLKCFAETPNKKNKITMMAEPLEKQLDEDIENEVVQIGWNRRRLGEFFQTKYNWDLLAARSIWAFGPDTTGPNILLDDTLPSEVDKHLLSTVRESLVQGFQWATREGPLCEEPIRQVKFKLLDAAIATEPLYRGGGQMIPTARRCAYSAFLMATPRLMEPYYTVEVVAPADCVAAVYTVLAKRRGHVTTDAPMPGSPMYTISAYIPVMDSFGFETDLRIHTQGQAFCMSAFHHWQLVPGDPLDKSIVIKTLDVQPTPHLAREFMIKTRRRKGLSEDVSVNKFFDDPMLLELAKQQDYTGF

Entity 7 Entity 7 polymer

Description description	Protein isy-1
Molecular weight formula_weight	31326.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	D

MARNAEKAMTALARWRRMKEEEERGPIARRPHDVKDCRNLSDAERFRREIVRDASKKITAIQNPGLGEFKLRDLNDEVNRLIKLKHAWEQRIRELGGTDYRKYAQKELDAIGRETGNSRGYKYFGAAKDLPGVRELFEKSTEGEEQRRHRADLLRNIDAHYFGYLDDEDGRLIPLEKLIEEKNIERINKEFAEKQAQKQQTASDAAPENIYKVEEDDDDDLETQESTVIGEDGRPMTIRHVLLPTQQDIEEMLLEQKKQELMAKYLD

Entity 8 Entity 8 polymer

Description description	WD_REPEATS_REGION domain-containing protein
Molecular weight formula_weight	36865.6 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	E

MALVTSSGQQLVSSGFPQQTAQRFSNLMAPTMVLLGHEGEIYTGAFSPDGTCLATSGYDQKIFFWNVYGECENFSTIKGHSGAVMDLKFTTDSSSLVSCGTDKSVRVWDMETGTCARRFRTHTDFVNAVHPSRRGVTLVASASDDGTCRVHDMRTKEPVKTYTNRYQQTAVTFNDSSDQVISGGIDNVLKVWDMRRDEITYTLTGHRDTITGISLSPSGKFIISNSMDCTVRQWDIRPFVPGQRSVGVFAGHNHNFEKNLLKCSWSPCERFITAGSSDRFLYVWETLSKKIVYKLPGHMGSVNCTDFHPKEPIMLSCGSDKRVFLGEIDMS

Entity 9 Entity 9 polymer

Description description	Pre-mRNA-splicing factor SYF1
Molecular weight formula_weight	99675.1 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	I

MADKENATKIEKMPNSETMKGISSEDVPFEEDIIRNPTSVNCWQRYIDHKLQNKSPAKQMFLIYERALAVFERSYKLWYHYLKYRESTIVNKCPTDNSWRALCDTYERCLMRLHKMPRIWICYCEVMIKRGLITETRRVFDRALRSLPVTQHMRIWTLYIGFLTSHDLPETTIRVYRRYLKMNPKAREDYVEYLIERDQIDEAAKELTTLVNQDQNVSEKGRTAHQLWTQLCDLISKNPVKIFSLNVDAIIRQGIYRYTDQVGFLWCSLADYYIRSAEFERARDVYEEAIAKVSTVRDFAQVYDAYAAFEEREVSIMMQEVEQSGDPEEEVDLEWMFQRYQHLMERKNELMNSVLLRQNPHNVGEWLNRVNIYEGNYNKQIETFKEAVKSVNPKIQVGKVRDLWIGLAKLYEDNGDLDAARKTFETAVISQFGGVSELANVWCAYAEMEMKHKRAKAALTVMQRACVVPKPGDYENMQSVQARVHRSPILWAMYADYEECCGTVESCRKVYDKMIELRVASPQMIMNYAMFLEENEYFELAFQAYEKGIALFKWPGVFDIWNTYLVKFIKRYGGKKLERARDLFEQCLENCPPTHAKYIFLLYAKLEEEHGLARHALSIYNRACSGVDRADMHSMYNIYIKKVQEMYGIAQCRPIFERAISELPEDKSRAMSLRYAQLETTVGEIDRARAIYAHAAEISDPKVHVKFWDTWKNFEVAHGNEATVRDMLRVRRSVEASYNVNVTLTSVQMRVDAERKAQETTTSSNPMDSLDQQQQQPSDGAGSITQVSMNKGNISFVRGAGKTVQQNTTENPDEIDLDEDDDDEEDDGGDADISVKVVPAQIFGNLKLAEEEEEA

Entity 10 Entity 10 polymer

Description description	TPR_REGION domain-containing protein
Molecular weight formula_weight	88116.0 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	J

MSDDEAAVPGNKPIRLPKKAAKVKNKAPAQLQITAEQLLREAKERELELIPPAPKTKITDPDELKEYQRKKRKEFEDGIRKNRMQLANWIKYGKWEESIGEIQRARSVFERALDVDHRSISIWLQYAEMEMRCKQINHARNVFDRAITIMPRAMQFWLKYSYMEEVIENIPGARQIFERWIEWEPPEQAWQTYINFELRYKEIDRARSVYQRFLHVHGINVQNWIKYAKFEERNGYIGNARAAYEKAMEYFGEEDINETVLVAFALFEERQKEHERARGIFKYGLDNLPSNRTEEIFKHYTQHEKKFGERVGIEDVIISKRKTQYEKMVEENGYNYDAWFDYLRLLENEETDREEVEDVYERAIANIPPHSEKRYWRRYIYLWINYALYEELVAKDFDRARQVYKACIDIIPHKTFTFAKVWIMFAHFEIRQLDLNAARKIMGVAIGKCPKDKLFRAYIDLELQLREFDRCRKLYEKFLESSPESSQTWIKFAELETLLGDTDRSRAVFTIAVQQPALDMPELLWKAYIDFEIACEEHEKARDLYETLLQRTNHIKVWISMAEFEQTIGNFEGARKAFERANQSLENAEKEERLMLLEAWKECETKSGDQEALKRVETMMPRRVKKRRQIQTEDGVDAGWEEYFDYIFPQDQAAKGSFKLLEAAARWKREREEAAARAAQELDAPIPEGDDDEEKEEAGKDAEEKVREGDSDTDLSESSSSSDSESSSSSSSDSSDSSDDDEDK

Entity 11 Entity 11 polymer

Description description	Pre-mRNA-splicing factor SPF27
Molecular weight formula_weight	27679.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	K

MSSKPLALTGGSGSSQLQDDQVLVDALPYLDTEYNEADRQLAMKLVEHECKTFRPTKNYLTHLPVPDYDAFLTKCMLKEMDRMKKKEEMGKLDMSRCELPAPSAVKGVDRKLWAKVLRNAKAQNEHLLMRQINLELMDEYAAESYLQRNKVMEDLLTHAEKELRKTKEAVMEVHANRKMAQLKAGEKVKQLEQSWVSMVTNNYRMEMENRQIDSDNRKQIKALKLDPTKLDDKEDQEN

Entity 12 Entity 12 polymer

Description description	Cell division cycle 5-like protein
Molecular weight formula_weight	85843.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	L

MVRVIIKGGVWKNTEDEILKAAIMKYGKNQWSRIASLLHRKSAKQCKARWFEWLDPGIKKTEWSREEDEKLLHLAKLMPTQWRTIAPIVGRTSAQCLERYEHLLDEAQRKAEGLDEEATETRKLKPGEIDPTPETKPARPDPIDMDDDELEMLSEARARLANTQGKKAKRKARERQLSDARRLASLQKRREMRAAGLAFARKFKPKRNQIDYSEEIPFEKHVPAGFHNPSEDRYVVEDANQKAIEDHQKPRGREIEMEMRREDREKLKKRKEQGEADAVFNIKEKKRSKLVLPEPQISDRELEQIVKIGHASDSVRQYIDGTATSGLLTDYTESARANAVAARTMRTPMLKDTVQLELENLMALQNTESALKGGLNTPLHESELGKGVLPTPKVAATPNTVLHAIAATPGTQSQFPGSTPGGFATPAGSVAATPFRDQMRINEEIAGSALEQKASLKRALASLPTPKNDFEVVGPDDDEVEGAVEDESNQDEDGWIEDASERAENKAKRNAENRVRNMKMRSQVIQRSLPKPTKVNEQATRATNSSADDMVKAEMSKLLAWDVDNKPPSVIYSREELDAAADLIKQEAESGPELNSLMWKVVEQCTSEIILSKDKFTRIAILPREEQMKALNDEFQMYRGWMNQRAKRAAKVEKKLRVKLGGYQAIHDKLCKKYQEVTTEIEMANIEKKTFERLGEHELKAINKRVGRLQQEVTTQETREKDLQKMYSKLSNKQWKLSQIEIHDAASTTSAPITY

Entity 13 Entity 13 polymer

Description description	Pre-mRNA-splicing factor syf-2
Molecular weight formula_weight	27719.0 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	M

MSSESQSSSSGPSSSGSKMKDFNQRFRDLHKLRQRARKENHEQVVEEDRRSKLPKNHEAKKERDQWQVKELQDRKAAEDKGLDYERVRSLEMSADVTEKLEQKRKRKKNPDQGFTSYEDMTLRQHTRLTAALDPDLDSYKKMRECVGGEQFYPTADTLIHGNHYPTTAAMDKLTKDVHGQVKRREQYHRRRLYDPDAPIDYINEKNKKFNKKLDKYYGKYTEDIKDDLERGTAI

Entity 14 Entity 14 polymer

Description description	Protein BUD31 homolog
Molecular weight formula_weight	17153.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	N

MSLATKLRRVRKSPPEGWDLIEPTLEQFEAKMREAETEPHEGKRKTEINWPIFRIHHQRSRYVYDMYYKKAEISRELYEFCLTAKFADAALIAKWKKQGYENLCCVKCVNTRDSNFGTACICRVPKSKLDAERVIECVHCGCHGCSG

Entity 15 Entity 15 polymer

Description description	Pre-mRNA-splicing factor RBM22
Molecular weight formula_weight	45902.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	O

MSMSKSSYSQYNRKNWEDSDFPILCETCLGNNPYMRMMKDKYGRECKICERPFTTFRWQPGKGARYKNTELCQTCAKVKNVCQTCMFDLEYGLPVQVRDHELQIADNIPKQGANRDFFLQNVERTLGQGDGTQPIAQIANNMDQAAHDRLRRMGRTQPYYKRNAPHICSFFVKGECKRGEECPYRHEKPTDPDDPLSRQNIRDRYYGTNDPVAEKILNRAAAAPTLSPPADTTITTLYIGNLGPSGAQQVTEKDLNDFFYQYGDIRCLRVLTEKGCAFIEFTTREAAERAAERSFNKTFIKGKRLTIRWGEPQAKRAADNSNYVTPVPSVPILPVPDGLAPSTSSQQRFTGSMPRPPAPPTFAAPRSLVVPNVRPVKAGESSGASSSSSIYYPSQDPTRLGAKGDVIE

Entity 16 Entity 16 polymer

Description description	Spliceosome-associated protein CWC15 homolog
Molecular weight formula_weight	26154.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	P

MTTAHRPTFHPARGGTARGEGDLSKLSNQYSSKDMPSHTKMKYRQTGQETEADLRKKDLRRELEDKERNAIREKRARDSASSSSSHSKRQRMDQIAAESAASVDADEAVDELNSSDDDDSDEDDTAALMAELEKIKKERAEEKAARDEEIKEKEEKQRMENILAGNPLLNDTPAGSSTSGGDFTVKRRWDDDVVFKNCAKGVEERKKEVTFINDAIRSEFHKKFMDKYIK

Entity 17 Entity 17 polymer

Description description	GCF C-terminal domain-containing protein
Molecular weight formula_weight	94244.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	PX

MFRKPKAKGAIRQRKSDGWDEPDAENQQVVSAIEVKQPAVPRPAMSFDADEGADSTFKLKKDKKKVEELKRQHKLEEEAEKLYKEEKIRKEALDKIVKKEKLSKEDKKTKNERHKYLDKYRDKSAKHISNSESYEYEENLDIDAEAISSVSNKFNSAFEGIPDSRAVFEAKKRRERARREGNQDGYIPLDDTQKLKSKSERNRLIREDENDDSDEECTNKFYSARELLRTEEDRRREEQEGFLERENGDIDEAERIKGDDDSENEEWEKQQIRKAVSRREIGQLRTEKRNTSKLFGHTVPVEDDTAMDMDIDLDMDVQVIGKPEFTGPSNTGGVVKIEDILAKLKLRIQERDEALNFRKEEKRKLEQNIEENKSMIAKIEMELPNQSTKYTMYQELRVYSRSLLECLNEKVGEINSIIDKKRDCGKSRTSRLSVRRRQDMRDQHAECMQGRNARMGEAAGRAAERDARRGRRRREREFTLARINHEEGLSTDDEEPTPQSMNDQKICDEVEAVASVLFADALDEYSDLRKVFGRMTDWLAVDPKSFQDAYVYLCIPKLSSPYVRLQILRADFLRKETILTSMQWFHIAMLAGSENAEIDQSHEILVELAPAIVEKVVIPFLIDTVKEEWDPMSLRQTRHLTTFCSLFEKLPNLTEKSKQFNAFLNAIRERICDCISEDLFMPIFMPNALEQPICRQFHDRQFWTCIKLIKSINALSPLISIAARFELVVEKCVNSQCVMALRTGSKNDVTAERKVRGLLAELDDSLLKMGGRTSFRQLIGTLELIAEEQSKAGRSFHKEIRKFLEKLER

Entity 18 Entity 18 polymer

Description description	Intron-binding protein aquarius
Molecular weight formula_weight	170397.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Q

MVTKRHQEAVVTRGAIENDTISAVAAKFWAPFTAETHENFDAKLIDTIYDNEMLKTSFNSRKIMMLEFSQYLEAYLWPNYVPEKASKAWNMSIVVMINEKFRERNLDSWNCFTKKSEHFPHFFKSILQLSLQEEGLASSEHCALLTFLVNAFGSVETPIVHKETRKLVSIEIWAGLLDSQREDLFKKQKKLKKIWENVRQKMTAAAADNNEFERTYLWNLIEKFKRVLNSLEPNEAQESEEGEVRDPIDSIKYCERFIELLIDLESILQTRRFFNSVLHSSHILTHCLLSSLISTDAGSLFFQLVQLLKFYARFEIDDLSGRQLTHKEVSEQHYQSVTRLQKAAFRLFNETMKEFYVLNVSGVDTRRALQKQFGDMNHAEVYRFAEYLHLVPAFGEDPNHQTSLLHLYPHQHLVETITLHCERRPNQLTQLNEKPLFPTEKVIWDENIIPYENYTGDGVLALDKLNLQFLTLHDYLLRNFNLFQLESTYEIRQDLEDVLFRMKPFQHESRNETVFSGWARMALQIDHFQISEVAKPLVGEKSPAVVRGVVTVNIGRRQDIRQEWENLRKHDVCFLVACRSRKSASGLKFDVRRPFSEQIEVLSVRGCDVEGMLDQDGHLLEEFTAWEKKAKIPGDLRKFRLLLDPNQYRIDMEQGTKDDIYDTFNLIVRRDSKTNNFKAVLQTIRDLLNTECVVPDWLTDVILGYGEPDSAHYSKLSSAVPELDFNDTFLSFAHVKESFPGYKIELADGFDEKEAVPPFKLEFKELERRQDVEIKPGELRTILVTPLTRKKVTPYSYDPRKNQVKFTPSQVEAIKSGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNWPNQRTLIVTHSNQALNQLFEKIIALDVDERHLLRMGHGEEALETEKDFSRYGRVNYVLKERLQLLNCVEKLAKALKIVGDVAYTCENAGYFFRFSVCRVWEEFLAKVTSKGCNKLAEGIISEIFPFTGFFKDIPDLFSGNNSADLKVAHSCWRHIEQIFEKLDEFRAFELLRNGRDRTEYLLVKEAKIIAMTCTHAALRRNELVKLGFRYDNIVMEEAAQILEVETFIPLLLQNPQDGHNRLKRWIMIGDHHQLPPVVQNQAFQKYSNMEQSLFARLVRLSVPNVQLDRQGRARAQIAELYQWRYNGLGNLPHVDGLPQFQNANAGFAFPFQFIDIPDFNGHGETQPSPHFYQNLGEAEYACALYTYMRILGYPAEKISILTTYNGQAQLIRDVFQRRCDTNPLIGMPAKVSTVDKYQGQQNDFIILSLVKTRNIGHIRDVRRLVVALSRARLGLYVLGRSKVFMDCLELTPAMRIFAKYPRKLVILPFEAHPTIRKWNERSKDGEPMEIQDTLHMTHFVHEFYMSNLPAMRDAYEQAMNEYMESQRLLNPPIDETQMDVETEHEKKHREAMERKKKQEMDDKKEADIHFEDMDHEMQEPAATAAPAPGAPAVEEPPPK

Entity 19 Entity 19 polymer

Description description	Uncharacterized protein T27F2.1
Molecular weight formula_weight	60303.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	R

MSMKLRDILPAPVAADEAASQIRRDPWFGGRDNEPSAALVSKEPPPYGKRTSFRPRGPEDFGDGGAFPEIHVAQFPLGLGLGDMRGKPENTLALQYGTDGKLQHDAIARIGHVKDKVVYSKLNDMKAKTWNEDDDDIQKPDDDAVIDATEKTRMALEKIVNSKVASALPVRHADKLAPAQYIRYTPSQQNGAAGSQQRIIRMVEEQKDPMEPPKFKINQKIPRAPPSPPAPVMHSPPRKMTAKDQNDWKIPPCISNWKNPKGFTVGLDKRLAADGRGLQQTHINENFAKLADALYIADRKAREEVETRAQLERRVAQNKKSEQEAKMAEAAAKARQERSAMRRKDDEDDEQVKVREEIRRDRLDDIRKERNIARSRPDKADKLRKERERDISEKIVLGLPDTNQKRTGEPQFDQRLFDKTQGLDSGAMDDDTYNPYDAAWRGGDSVQQHVYRPSKNLDNDVYGGDLDKIIEQKNRFVADKGFSGAEGSSRGSGPVQFEKDQDVFGLSSLFEHTKEKKRGGDGGDSRGESKRSRRD

Entity 20 Entity 20 polymer

Description description	Peptidyl-prolyl cis-trans isomerase
Molecular weight formula_weight	18547.0 kDa
EC 编号 ec_number	5.2.1.8
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	S

MPAPINDQAPYVILDTTMGKIALELYWNHAPRTCQNFSQLAKRNYYNGTIFHRIIADFMIQGGDPTGTGRGGASIYGDKFSDEIDERLKHTGAGILSMANAGPNTNGSQFFITLAPTQHLDGKHTIFGRVAAGMKVIANMGRVDTDNHDRPKIEIRILKAYPSESSVLS

Entity 21 Entity 21 polymer

Description description	WD_REPEATS_REGION domain-containing protein
Molecular weight formula_weight	54766.2 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	T

MSASVSDPYEQMPAAPTDDDLEDKPEADKKALLNQVFKSLKRAQDLFYHDYAQPPPMPEENDSLIRSMKRKHEYGNVIKKVEEMKVRRENEMLALPTSQPMHGTGSVIASAGTPLAITDGSGKLVNQQQGSAKSGTLLPLVPLGNSSKGEDNTTRSLLPSKAPMMMKPKWHAPWKLYRVASGHTGWVRAVDVEPGNQWFASGGADRIIKIWDLASGQLKLSLTGHISSVRAVKVSPRHPFLFSGGEDKQVKCWDLEYNKVIRHYHGHLSAVQALSVHPSLDVLVTCARDSTARVWDMRTKAQVHCFAGHTNTVADVVCQSVDPQVITASHDATVRLWDLAAGRSMCTLTHHKKSVRALTIHPRLNMFASASPDNIKQWKLPKGEFMQNLSGHNAIINTLSSNDDGVVVSGADNGSLCFWDWRSGFCFQKIQTKPQPGSIESEAGIYASCFDKTGLRLITAEADKTIKMYKEDDEATEESHPIVWRPEIVKKKAY

Entity 22 Entity 22 polymer

Description description	Septin and tuftelin-interacting protein 1 homolog
Molecular weight formula_weight	94421.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	TF

MEDDDGRESFEINDMDLEYAMNPGGRRRFQNKDQATYGVFAPDSDDDDDEQGTSRGPYKKRSKISAPMSFVSGGIQQGNKIDKDDPASLNLNLGGEKKPKEDDEGSIQIDFDKRTKKAPKQNGAQVFAGMRSSANHGAADINQFGSWMRGDGNSNKIMKMMQAMGYKPGEGLGAQGQGIVEPVQAQLRKGRGAVGAYGKESTATGPKFGESAADAQKRMAQEGTSSRPTNDDQEKSGLKIKGSWKKSQTVKTKYRTIEDVMEEGMSASRPASHQQSQQYSNIKVIDMTGKQQKIYSGYDSFSMKTRSEYDTVDDEERTVFDVPELIHNLNLLVDLTEEGIRRSNQQLISLKDQTTALEYDLQQVQKSLGTEEQEAQHIKDVYELIDGFSSNRSPSMEECQELFRRLRSEFPHEYELYSLETVAIPTVLPLIQKYFVAWKPLEDKNYGCELISTWRDILDDSKNGRKMTFGHNKTKGDEIRAYDRIIWEGILPSIRRACLQWDPSTQMHEMIELVEQWIPLLSAWITENILEQLVVPKIAERVNQWDPMTDEIPIHEWLVPWLVLLGDRIQTVMPPIRQKLSKALKLWDPMDRSALETLRPWQNVWSAATFSAFIAQNIVPKLGVALDTMELNPTMNPEYPEWTACMEWLEFTHPDAIANIVTKYFFPRFYNCLCLWLDSPGVDYNEVKRWYGSWKARIPQVLVNYPTVNENLRRSMIAIGRSLQGEKVGGLQATPIAPMAPPPPMAPHFTQAAPVQKLSLKEIIEYTAGKNGFTYHPQKDRYKDGRQVFWFGALSIYLDSEMVYVMDPIEFVWRPSGLNELIQMAQGAQG

Entity 23 Entity 23 polymer

Description description	WD_REPEATS_REGION domain-containing protein
Molecular weight formula_weight	65385.7 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	W

MDALQAYGGSDSEHSDDDASMDQVAKGKSSTLLERAIVTAPDVESKSAIRQVAIVDPKTKEIKSNPKFDQLFKPESGPVNHFKSEQQRSQKNTLTGFVEPAHLNEFHFNRQIRSFDTLGYAQNPTAESGTTHFVGDVKKAEAEKGVSLFESKKTGGEKRKRVRNDDSADIDGYTGPWSRFIDEKTVAKPTPELQKQMDEIVKKRQEKSRRFKKEKEDSEQMAEESSTLHLKEAEDYQGRSFLVPPSFTGVNLREDYVPERCFVPKKLVHTYRGHNKGVNFLQWFPKSAHLFLSCSMDTKIKLWEVYDRQRVVRTYAGHKLPVREVAFNNEGTEFLSASFDRYVKLWDTETGQVKQRFHTGHVPYCLKYHPDDDKNHMFLVGMQNKKIIQWDSRSGEIVQEYDRHLQAVNSITFFDKNRRFASTSDDKSVRIWEWEIPVDTKLIQNVGLHAIPTMTKSPNDKWVVGQCMDNRIVLFQLVDDKLRFSKKKAFRGHNAAGYACNIDFSPDQSFLISGDADGKLFIWDWRTHKIVGKWKAHDSTCIAALWHPHEKSRMITAGWDGLIKMWN

Entity 24 Entity 24 polymer

Description description	Coiled-coil domain-containing protein 12
Molecular weight formula_weight	19138.5 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	Z

MTDKNNSDSDEDIESLTNHETSLEAAAKARKRRLLAMKSKIHGIEMQEEDYDEGETSTKKSREVGREFRNHKPDDAVGTQNVDMDLDIVQREITEHLKDVLHEKAIDSVDLAMLAPKKIDWDLKRDIESKLQKLERRTQKAVATIIRQRLAEGKGDLAATVNAAAAQNL

Entity 25 Entity 25 polymer

Description description	Small nuclear ribonucleoprotein Sm D3
Molecular weight formula_weight	14836.2 kDa
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	a,h

MTSVGVPIKILHEAEGHMVTLETVTGEVYRGKLSEAEDNMNCQLAETVVTFRDGRSHQLDNVFIRGNKIRFMILPDMLKNAPMFKNIGRAQKGAIGMGLGGLDQRGRGRGTAFRRPMGRGGPRGMSRPGGAPTFRG

Entity 26 Entity 26 polymer

Description description	Probable small nuclear ribonucleoprotein-associated protein B
Molecular weight formula_weight	16768.6 kDa
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	b,i

MTISKNNKMMAHLNYRMKIILQDGRTFIGFFKAFDKHMNILLAECEEHRQIKPKAGKKTDGEEKRILGLVLVRGEHIVSMTVDGPPPRDDDSVRLAKAGGAGGVGQAKPGGRGMPAMPGMPGMPPGGAPGGLSGAMRGHGGPGMAAMQPGYGGPPGGRPF

Entity 27 Entity 27 polymer

Description description	Small nuclear ribonucleoprotein Sm D1
Molecular weight formula_weight	13724.1 kDa
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	c,j

MKLVRFLMKLSHETVNIELKNGTQVSGTIMGVDVAMNTHLRAVSMTVKNKEPVKLDTLSIRGNNIRYIILPDPLALDTLLIDDEPRKKARAARAGASRGRGGRGGMRGGRGGRGRGRGGPRGAGPRR

Entity 28 Entity 28 polymer

Description description	Probable small nuclear ribonucleoprotein Sm D2
Molecular weight formula_weight	13291.5 kDa
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	d,k

MSAQAKPRSEMTAEELAAKEDEEFNVGPLSILTNSVKNNHQVLINCRNNKKLLGRVKAFDRHCNMVLENVKEMWTEVPKTGKGKKKAKSVAKDRFISKMFLRGDSVILVVKNPLAQAE

Entity 29 Entity 29 polymer

Description description	Probable small nuclear ribonucleoprotein E
Molecular weight formula_weight	10625.3 kDa
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	e,l

MSTRKLNKVMVQPVNLIFRYLQNRTRVQIWLYEDVTHRLEGYIIGFDEFMNVVFDEAEEVNMKTKGRNKIGRILLKGDNITLIHAAQQEA

Entity 30 Entity 30 polymer

Description description	Probable small nuclear ribonucleoprotein F
Molecular weight formula_weight	9256.5 kDa
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	f,m

MSAVQPVNPKPFLNSLTGKFVVCKLKWGMEYKGVLVAVDSYMNLQLAHAEEYIDGNSQGNLGEILIRCNNVLYVGGVDGENETSA

Entity 31 Entity 31 polymer

Description description	Probable small nuclear ribonucleoprotein G
Molecular weight formula_weight	8756.2 kDa
Source method src_method	nat
Copy count entity_count	2

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	g,n

MSKTHPPELKKYMDKEMDLKLNGNRRVSGILRGFDPFMNMVIDEAVEYQKDGGSVNLGMTVIRGNSVVIMEPKERIS

Entity 32 Entity 32 polymer

Description description	;Probable U2 small nuclear ribonucleoprotein A' ;
Molecular weight formula_weight	28905.9 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	o

MVRLTTELFAERPQFVNSVNMREINLRGQKIPVIENMGVTRDQFDVIDLTDNDIRKLDNFPTFSRLNTLYLHNNRINYIAPDIATKLPNLKTLALTNNNICELGDIEPLAECKKLEYVTFIGNPITHKDNYRMYMIYKLPTVRVIDFNRVRLTEREAAKKMFKGKSGKKARDAIQKSVHTEDPSEIEPNENSSGGGARLTDEDREKIKEAIKNAKSLSEVNYLQSILASGKVPEKGWNRQMDQNGADGEAMES

Entity 33 Entity 33 polymer

Description description	RRM domain-containing protein
Molecular weight formula_weight	24881.3 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	p

MADINPNHTIYVNNLNEKVKKDELKRSLHMVFTQFGEIIQLMSFRKEKMRGQAHIVFKEVSSASNALRALQGFPFYGKPMRIQYAREDSDVISRAKGTFVEKRQKSTKIAKKPYEKPAKNGKSAAEPTQKEPQETDGPGLPNNILFCSNIPEGTEPEQIQTIFSQFPGLREVRWMPNTKDFAFIEYESEDLSEPARQALDNFRITPTQQITVKFASK

Entity 34 Entity 34 polymer

Description description	Pre-mRNA-processing factor 19
Molecular weight formula_weight	53272.6 kDa
EC 编号 ec_number	2.3.2.27
Source method src_method	nat
Copy count entity_count	4

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	q,r,s,t

MSFVCGISGELTEDPVVSQVSGHIFDRRLIVKFIAENGTDPISHGELSEDQLVSLKSGGTGSAPRNVSGTSIPSLLKMLQDEWDTVMLNSFSLRQQLQIARQELSHSLYQHDAACRVISRLSKELTAAREALSTLKPHTSAKVDDDVSIDESEDQQGLSEAILAKLEEKSKSLTAERKQRGKNLPEGLAKTEELAELKQTASHTGIHSTGTPGITALDIKGNLSLTGGIDKTVVLYDYEKEQVMQTFKGHNKKINAVVLHPDNITAISASADSHIRVWSATDSSSKAIIDVHQAPVTDISLNASGDYILSASDDSYWAFSDIRSGKSLCKVSVEPGSQIAVHSIEFHPDGLIFGTGAADAVVKIWDLKNQTVAAAFPGHTAAVRSIAFSENGYYLATGSEDGEVKLWDLRKLKNLKTFANEEKQPINSLSFDMTGTFLGIGGQKVQVLHVKSWSEVVSLSDHSGPVTGVRFGENARSLVTCSLDKSLRVFSF

Entity 35 Entity 35 polymer

Description description	Peptidyl-prolyl cis-trans isomerase E
Molecular weight formula_weight	36469.3 kDa
EC 编号 ec_number	5.2.1.8
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polypeptide(L)
Chain IDs strand_id	y

MNTNFPHNRKRTLYVGGFTEDVTEKVLMAAFIPFGDVVAISIPMDYESGKHRGFGFVEFDMAEDAAMAIDNMNESELFGKTIRVNFARPPKATERSQKPVWADDEWLKKYGRGGEAAAEEDGDAEKAATSSSSASTKLPRVYLGVKIGIRYIGRIVIELRTDVTPKTAENFRCLCTGERGFGYEGSIFHRIIPKFMLQGGDFTKGDGTGGKSIYGTKFDDENFTLRHTMPGTVSMANCGANTNGSQFFICTEKTDWLDGKHVVFGHVVEGMNIVRQVEQQGTPSGKPQMVVKIVESGEIEPEKRIAAEKLAQKAVVPGAEIQEPLPQAMET

Entity 36 Entity 36 polymer

Description description	Intron lariat RNA
Molecular weight formula_weight	3680.8 kDa
Source method src_method	nat
Copy count entity_count	1

Polymer Polymer

Polymer type type	polydeoxyribonucleotide
Chain IDs strand_id	In

NNNNNNNNNNNNNNNNNNN

Entity 37 Entity 37 non-polymer

Description description	MAGNESIUM ION
Molecular weight formula_weight	24.3 kDa
Source method src_method	syn
Copy count entity_count	7

Entity 38 Entity 38 non-polymer

Description description	INOSITOL HEXAKISPHOSPHATE
Molecular weight formula_weight	660.0 kDa
Source method src_method	syn
Copy count entity_count	2

Entity 39 Entity 39 non-polymer

Description description	GUANOSINE-5'-TRIPHOSPHATE
Molecular weight formula_weight	523.2 kDa
Source method src_method	syn
Copy count entity_count	1

Entity 40 Entity 40 non-polymer

Description description	ZINC ION
Molecular weight formula_weight	65.4 kDa
Source method src_method	syn
Copy count entity_count	6

▶

Resolution resolution	2.90 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	879523

Structure of the C. elegans Intron Lariat Spliceosome primed for disassembly (ILS')

1. Protein Identity and Related Structures Protein Identity & Related Structures

Pre-mRNA-splicing factor 8 homolog

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

U5 small nuclear ribonucleoprotein 200 kDa helicase

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Tr-type G domain-containing protein

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Protein isy-1

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

WD_REPEATS_REGION domain-containing protein

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Pre-mRNA-splicing factor SYF1

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

TPR_REGION domain-containing protein

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Pre-mRNA-splicing factor SPF27

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Cell division cycle 5-like protein

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

Pre-mRNA-splicing factor syf-2

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer