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8ssw

Crystal structure of DEAD-box RNA helicase DDX3X in complex with ADP at pre-unwound state

Method: X-RAY DIFFRACTION
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1. Protein Identity and Related Structures Protein Identity & Related Structures

ATP-dependent RNA helicase DDX3X

Homo sapiens

UniProt O00571

State in the Current Structure

Assembly Physical composition Protein state Molecular copy count Associated components Data consistency
1 Protein–RNA Homooligomer Protein 2 RNA 2 RNA (28-MER) × 2 ADENOSINE-5'-DIPHOSPHATE × 2 MAGNESIUM ION × 2 1,2-ETHANEDIOL × 4 water × 4 Consistent with all polymers

Other States of the Same Protein in the Database

Monomer
2i4i 2jgn 2jgn 2jgn 3jrv 4px9 4px9 4px9 4pxa 5e7i 5e7i 5e7i

16 assemblies; showing the first 12

Homodimer
7ymf

1 assemblies

Homotetramer

None

Other homooligomers

None

Heteromeric or nucleic-acid complex
3jrv 3jrv 4o2c 4o2e 4o2e 4o2f 4o2f 6o5f 7liu 8ssw

10 assemblies

View Construct and Data Evidence
UniProt name DDX3X_HUMAN
Isoform —
PDB entities 1
Chains and sequence ranges Author chain A； PDBConstruct 1–476； UniProt 132–607 Author chain B； PDBConstruct 1–476； UniProt 132–607

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id8ssw
Deposition date deposition_date2023-05-09
Last revision last_revision2024-05-22
Structure title titleCrystal structure of DEAD-box RNA helicase DDX3X in complex with ADP at pre-unwound state
Keywords keywordsDEAD-box RNA helicase, DDX3X, pre-unwound state, RNA BINDING PROTEIN, RNA BINDING PROTEIN-RNA complex; RNA BINDING PROTEIN/RNA
Experimental Method methodX-RAY DIFFRACTION
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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8ssw__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8ssw__assembly_1__model_1 | I(q)

10-2 10-1 106 107 108 q (1/Angstrom) I(q)
100 plotted points; both axes use logarithmic scales.

8ssw__assembly_1__model_1 | P(r) · Pending

The new assembly/model P(r) has not been calculated yet This placeholder does not display legacy data r (Angstrom) P(r)
P(r) will be calculated and displayed separately for the same assembly/model.
Rg（Guinier）33.65 Å
Rg (electron density)33.83 Å
Total Rg34.21 Å
Atom count7996
Residues918
Excluded volume138270 ų
Maximum q0.500 Å⁻¹
Assembly Model Structure unit Oligomeric description Status CRYSOL Actions
1 1 8ssw__assembly_1__model_1 tetrameric （4） Success 4.1.3-1-20251215 (887e7ef) View Download
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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (6)

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7. Citations (1)