SAXSdb — 8teq

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1. Protein Identity and Related Structures Protein Identity & Related Structures

TRK-fused gene protein Low Complexity Domain G269V mutant

Homo sapiens

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Insufficient information	Homooligomer	Protein 30	No other associated polymer	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	A0A2U3DNX3_PURLI
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain 0； PDBConstruct 26–261； UniProt 1–236 Author chain 1； PDBConstruct 26–261； UniProt 1–236 Author chain 2； PDBConstruct 26–261； UniProt 1–236 Author chain 3； PDBConstruct 26–261； UniProt 1–236 Author chain A； PDBConstruct 26–261； UniProt 1–236 Author chain B； PDBConstruct 26–261； UniProt 1–236 Author chain C； PDBConstruct 26–261； UniProt 1–236 Author chain D； PDBConstruct 26–261； UniProt 1–236 Author chain E； PDBConstruct 26–261； UniProt 1–236 Author chain F； PDBConstruct 26–261； UniProt 1–236 Author chain G； PDBConstruct 26–261； UniProt 1–236 Author chain H； PDBConstruct 26–261； UniProt 1–236 Author chain I； PDBConstruct 26–261； UniProt 1–236 Author chain J； PDBConstruct 26–261； UniProt 1–236 Author chain K； PDBConstruct 26–261； UniProt 1–236 Author chain L； PDBConstruct 26–261； UniProt 1–236 Author chain M； PDBConstruct 26–261； UniProt 1–236 Author chain N； PDBConstruct 26–261； UniProt 1–236 Author chain O； PDBConstruct 26–261； UniProt 1–236 Author chain P； PDBConstruct 26–261； UniProt 1–236 Author chain Q； PDBConstruct 26–261； UniProt 1–236 Author chain R； PDBConstruct 26–261； UniProt 1–236 Author chain S； PDBConstruct 26–261； UniProt 1–236 Author chain T； PDBConstruct 26–261； UniProt 1–236 Author chain U； PDBConstruct 26–261； UniProt 1–236 Author chain V； PDBConstruct 26–261； UniProt 1–236 Author chain W； PDBConstruct 26–261； UniProt 1–236 Author chain X； PDBConstruct 26–261； UniProt 1–236 Author chain Y； PDBConstruct 26–261； UniProt 1–236 Author chain Z； PDBConstruct 26–261； UniProt 1–236

TRK-fused gene protein Low Complexity Domain G269V mutant

Homo sapiens

UniProt Q92734

State in the Current Structure

Assembly	Physical composition	Protein state	Molecular copy count	Associated components	Data consistency
1	Insufficient information	Homooligomer	Protein 30	No other associated polymer	Consistent with protein count

Other States of the Same Protein in the Database

View Construct and Data Evidence

UniProt name	TFG_HUMAN
Isoform	—
PDB entities	1
Chains and sequence ranges	Author chain 0； PDBConstruct 268–358； UniProt 237–327 Author chain 1； PDBConstruct 268–358； UniProt 237–327 Author chain 2； PDBConstruct 268–358； UniProt 237–327 Author chain 3； PDBConstruct 268–358； UniProt 237–327 Author chain A； PDBConstruct 268–358； UniProt 237–327 Author chain B； PDBConstruct 268–358； UniProt 237–327 Author chain C； PDBConstruct 268–358； UniProt 237–327 Author chain D； PDBConstruct 268–358； UniProt 237–327 Author chain E； PDBConstruct 268–358； UniProt 237–327 Author chain F； PDBConstruct 268–358； UniProt 237–327 Author chain G； PDBConstruct 268–358； UniProt 237–327 Author chain H； PDBConstruct 268–358； UniProt 237–327 Author chain I； PDBConstruct 268–358； UniProt 237–327 Author chain J； PDBConstruct 268–358； UniProt 237–327 Author chain K； PDBConstruct 268–358； UniProt 237–327 Author chain L； PDBConstruct 268–358； UniProt 237–327 Author chain M； PDBConstruct 268–358； UniProt 237–327 Author chain N； PDBConstruct 268–358； UniProt 237–327 Author chain O； PDBConstruct 268–358； UniProt 237–327 Author chain P； PDBConstruct 268–358； UniProt 237–327 Author chain Q； PDBConstruct 268–358； UniProt 237–327 Author chain R； PDBConstruct 268–358； UniProt 237–327 Author chain S； PDBConstruct 268–358； UniProt 237–327 Author chain T； PDBConstruct 268–358； UniProt 237–327 Author chain U； PDBConstruct 268–358； UniProt 237–327 Author chain V； PDBConstruct 268–358； UniProt 237–327 Author chain W； PDBConstruct 268–358； UniProt 237–327 Author chain X； PDBConstruct 268–358； UniProt 237–327 Author chain Y； PDBConstruct 268–358； UniProt 237–327 Author chain Z； PDBConstruct 268–358； UniProt 237–327

The page prioritizes protein identity, the current assembly, associated components, oligomeric state and cross-PDB links. Chain mapping and sequence ranges are retained as data evidence. Internal IDs, import timestamps and assembly operation expressions are maintenance fields and are not shown here.

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2. Structure Basics 2. Structure Basics

Entry ID entry_id	8teq
Deposition date deposition_date	2023-07-06
Structure title title	Tropomyosin-receptor kinase fused gene protein (TRK-fused gene protein; TFG) Low Complexity Domain (residues 237-327) G269V mutant, amyloid fiber
Keywords keywords	;amyloid, mutation, Charcot-Marie-Tooth disease, Hereditary motor and sensory neuropathy with proximal dominant involvement, PROTEIN FIBRIL ;; PROTEIN FIBRIL
Experimental Method method	ELECTRON MICROSCOPY

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3. Official assembly/model SAXS Official SAXS Profiles

This page reads only the latest assembly calculations. Every curve maps to an explicit PDB entry, official biological assembly and coordinate model.

8teq__assembly_1__model_1

Assembly 1 · Model 1 · CRYSOL 4.1.3-1-20251215 (887e7ef)

Download this curve (.dat)

8teq__assembly_1__model_1 | I(q)

100 plotted points; both axes use logarithmic scales.

8teq__assembly_1__model_1 | P(r) · Pending

P(r) will be calculated and displayed separately for the same assembly/model.

Rg（Guinier）	27.89 Å
Rg (electron density)	27.30 Å
Total Rg	28.02 Å
Atom count	6705
Residues	825
Excluded volume	115440 Å³
Maximum q	0.500 Å⁻¹

Assembly	Model	Structure unit	Oligomeric description	Status	CRYSOL	Actions
1	1	`8teq__assembly_1__model_1`	30-meric （30）	Success	4.1.3-1-20251215 (887e7ef)	View Download

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4. Crystallography and Experiment 4. Crystallography & Experiment

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5. Entities and Polymers Entities & Polymers (1)

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Unit-cell length a length_a	1.000 Å
Unit-cell length b length_b	1.000 Å
Unit-cell length c length_c	1.000 Å
Unit-cell angle α angle_alpha	90.00 °
Unit-cell angle β angle_beta	90.00 °
Unit-cell angle γ angle_gamma	90.00 °
Molecules per unit cell Z z_pdb	—

Space group space_group	P 1
Space-group number int_tables_number	1
Crystal system crystal_system	triclinic

Resolution resolution	2.84 Å
Resolution测定Method resolution_method	—
颗粒数 num_particles	31643

Description description	TRK-fused gene protein Low Complexity Domain G269V mutant
Molecular weight formula_weight	40490.8 kDa
Mutation mutation	G269V
Source method src_method	man
Copy count entity_count	30

Polymer type type	polypeptide(L)
Chain IDs strand_id	A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,0,1,2,3
Atom count atom_count	6705

Tropomyosin-receptor kinase fused gene protein (TRK-fused gene protein; TFG) Low Complexity Domain (residues 237-327) G269V mutant, amyloid fiber

1. Protein Identity and Related Structures Protein Identity & Related Structures

TRK-fused gene protein Low Complexity Domain G269V mutant

State in the Current Structure

Other States of the Same Protein in the Database

TRK-fused gene protein Low Complexity Domain G269V mutant

State in the Current Structure

Other States of the Same Protein in the Database

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

8teq__assembly_1__model_1

8teq__assembly_1__model_1 | I(q)

8teq__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

冷冻电镜 EM 3D

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

7. Citations (1)

Source organism organism	Homo sapiens
Common name common_name	human
NCBI taxonomy ID ncbi_taxonomy_id	9606
Host organism host_organism	Escherichia coli BL21(DE3)

Tropomyosin-receptor kinase fused gene protein (TRK-fused gene protein; TFG) Low Complexity Domain (residues 237-327) G269V mutant, amyloid fiber

1. Protein Identity and Related Structures Protein Identity & Related Structures

TRK-fused gene protein Low Complexity Domain G269V mutant

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

TRK-fused gene protein Low Complexity Domain G269V mutant

State in the Current Structure

Other States of the Same Protein in the Database

Monomer

Homodimer

Homotetramer

Other homooligomers

Heteromeric or nucleic-acid complex

2. Structure Basics 2. Structure Basics

3. Official assembly/model SAXS Official SAXS Profiles

8teq__assembly_1__model_1

8teq__assembly_1__model_1 | I(q)

8teq__assembly_1__model_1 | P(r) · Pending

4. Crystallography and Experiment 4. Crystallography & Experiment

Unit cell Unit Cell

Symmetry Symmetry

冷冻电镜 EM 3D

5. Entities and Polymers Entities & Polymers (1)

Entity 1 Entity 1 polymer

Polymer Polymer

Source Source

7. Citations (1)