Retinol-binding protein 2
Homo sapiens
State in the Current Structure
| Assembly | Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Associated Components | Method and Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|
| 1 | Protein monomer Monomer Protein × 1 PDB declaration: monomeric（1） Consistent with protein copy count | Chain A； UniProt 2–134 | Mutation：Q108K:K40L:T51V:T53S:R58W | ACT ACETATE ION × 1 | X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, HANGING DROP；295 K；ammonium acetate, PEG 4000, sodium acetate | Resolution 1.50 Å R-free 0.237 |
| 2 | Protein monomer Monomer Protein × 1 PDB declaration: monomeric（1） Consistent with protein copy count | Chain B； UniProt 2–134 | Mutation：Q108K:K40L:T51V:T53S:R58W | ACT ACETATE ION × 1 A1AEQ (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal × 1 | X-RAY DIFFRACTION X-ray crystallization conditions：VAPOR DIFFUSION, HANGING DROP；295 K；ammonium acetate, PEG 4000, sodium acetate | Resolution 1.50 Å R-free 0.237 |
Other States of the Same Protein in the Database
Each row is a biological assembly of the same UniProt protein in another PDB entry. The “Difference from current entry” column identifies evidence-level differences; no tag means the currently parsed fields agree.
| Other PDB | Difference from Current Entry 8W02 | Assembly / Oligomeric State | Construct | Mutations and Modifications | Ligands, Ions and Non-polymers | Method and Experimental Conditions | Structure Quality |
|---|---|---|---|---|---|---|---|
| 12AK Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-6 Deposited 2026-03-23 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | A1CKY (2Z)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}-4,4,4-trifluorobut-2-enal × 1 ACT ACETATE ION × 1 EDO 1,2-ETHANEDIOL × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, ammonium acetate, sodium acetate 100 mM
|
Resolution 1.37 Å R-free 0.200 |
| 2RCQ Crystal structure of human apo Cellular Retinol Binding Protein II (CRBP-II) Deposited 2007-09-20 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | SO4 SULFATE ION × 2 TLA L(+)-TARTARIC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.6；293 K；0.1 M sodium citrate, 0.2 M sodium/potassium tartrate, 1.4 M ammonium sulphate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.20 Å R-free 0.217 |
| 2RCT Crystal structure of human holo cellular retinol-binding protein II (CRBP-II) Deposited 2007-09-20 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | SO4 SULFATE ION × 2 RTL RETINOL × 1 TLA L(+)-TARTARIC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 5.6；293 K；0.1 M sodium citrate, 0.2 M sodium/potassium tartrate, 1.4 M ammonium sulfate, pH 5.6, VAPOR DIFFUSION, HANGING DROP, temperature 293K
|
Resolution 1.20 Å R-free 0.215 |
| 4EDE Crystal Structure of the Q108K:K40L:T51V:T53C:Y19W:R58W:T29L:A33W Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.4 Angstrom Resolution Deposited 2012-03-27 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:Y19W:R58W:T29L:A33W | ACT ACETATE ION × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION, RECRYSTALLIZATION；pH 4.6；298 K；40% PEG4000, 0.1 M sodium acetate trihydrate, pH 4.6, 0.1 M ammonium acetate, EVAPORATION, RECRYSTALLIZATION, temperature 298K
|
Resolution 1.40 Å R-free 0.242 |
| 4EDE Crystal Structure of the Q108K:K40L:T51V:T53C:Y19W:R58W:T29L:A33W Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.4 Angstrom Resolution Deposited 2012-03-27 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:Y19W:R58W:T29L:A33W | ACT ACETATE ION × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION, RECRYSTALLIZATION；pH 4.6；298 K；40% PEG4000, 0.1 M sodium acetate trihydrate, pH 4.6, 0.1 M ammonium acetate, EVAPORATION, RECRYSTALLIZATION, temperature 298K
|
Resolution 1.40 Å R-free 0.242 |
| 4EEJ Crystal Structure of the Q108K:K40L:T51V:T53C:Y19W:R58W:T29L:Q4R Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.5 Angstrom Resolution Deposited 2012-03-28 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:Y19W:R58W:T29L:Q4R | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION, RECRYSTALLIZATION；pH 4.6；298 K；40% PEG4000, 0.1 M sodium acetate trihydrate, pH 4.6, 0.1 M ammonium acetate, EVAPORATION, RECRYSTALLIZATION, temperature 298K
|
Resolution 1.50 Å R-free 0.208 |
| 4EEJ Crystal Structure of the Q108K:K40L:T51V:T53C:Y19W:R58W:T29L:Q4R Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.5 Angstrom Resolution Deposited 2012-03-28 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:Y19W:R58W:T29L:Q4R | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION, RECRYSTALLIZATION；pH 4.6；298 K；40% PEG4000, 0.1 M sodium acetate trihydrate, pH 4.6, 0.1 M ammonium acetate, EVAPORATION, RECRYSTALLIZATION, temperature 298K
|
Resolution 1.50 Å R-free 0.208 |
| 4EFG Crystal Structure of the Q108K:K40L:T51V:T53C:Y19W:R58W:T29L Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.58 Angstrom Resolution Deposited 2012-03-29 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:Y19W:R58W:T29L | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION, RECRYSTALLIZATION；pH 4.6；298 K；40% PEG4000, 0.1 M sodium acetate trihydrate, pH 4.6, 0.1 M ammonium acetate, EVAPORATION, RECRYSTALLIZATION, temperature 298K
|
Resolution 1.58 Å R-free 0.242 |
| 4EFG Crystal Structure of the Q108K:K40L:T51V:T53C:Y19W:R58W:T29L Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.58 Angstrom Resolution Deposited 2012-03-29 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:Y19W:R58W:T29L | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION, RECRYSTALLIZATION；pH 4.6；298 K；40% PEG4000, 0.1 M sodium acetate trihydrate, pH 4.6, 0.1 M ammonium acetate, EVAPORATION, RECRYSTALLIZATION, temperature 298K
|
Resolution 1.58 Å R-free 0.242 |
| 4EXZ Crystal Structure of the Q108K:K40L Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.7 Angstrom Resolution Deposited 2012-05-01 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L | ACT ACETATE ION × 1 RET RETINAL × 1 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.61 Å R-free 0.265 |
| 4EXZ Crystal Structure of the Q108K:K40L Mutant of Cellular Retinol Binding Protein Type II in Complex with All-trans-Retinal at 1.7 Angstrom Resolution Deposited 2012-05-01 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L | ACT ACETATE ION × 1 RET RETINAL × 1 | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.61 Å R-free 0.265 |
| 4GKC Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal at 1.33 Deposited 2012-08-10 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K,K40L,T51V,T53C,Y19W,R58W,T29L,Q4A | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 4.6；298 K；40% PEG 4000, 0.1M CH3COONa.3H2O, 0.1 M CH3COONH4, EVAPORATION, temperature 298K, pH 4.6
|
Resolution 1.30 Å R-free 0.225 |
| 4GKC Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal at 1.33 Deposited 2012-08-10 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K,K40L,T51V,T53C,Y19W,R58W,T29L,Q4A | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 4.6；298 K；40% PEG 4000, 0.1M CH3COONa.3H2O, 0.1 M CH3COONH4, EVAPORATION, temperature 298K, pH 4.6
|
Resolution 1.30 Å R-free 0.225 |
| 4QYN The Crystal Structures of holo-wt human Cellular Retinol Binding protein II (hCRBPII) bound to Retinol Deposited 2014-07-24 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
Fragment：transfer protein
|
Not recorded | RTL RETINOL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 1.19 Å R-free 0.216 |
| 4QYN The Crystal Structures of holo-wt human Cellular Retinol Binding protein II (hCRBPII) bound to Retinol Deposited 2014-07-24 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
Fragment：transfer protein
|
Not recorded | RTL RETINOL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 1.19 Å R-free 0.216 |
| 4QYP The Crystal Structures of holo-wt human Cellular Retinol Binding protein II (hCRBPII) bound to Retinal Deposited 2014-07-25 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
Fragment：transfer protein
|
Not recorded | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 1.62 Å R-free 0.252 |
| 4QYP The Crystal Structures of holo-wt human Cellular Retinol Binding protein II (hCRBPII) bound to Retinal Deposited 2014-07-25 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
Fragment：transfer protein
|
Not recorded | RET RETINAL × 1 ACT ACETATE ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 1.62 Å R-free 0.252 |
| 4QYP The Crystal Structures of holo-wt human Cellular Retinol Binding protein II (hCRBPII) bound to Retinal Deposited 2014-07-25 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
Fragment：transfer protein
|
Not recorded | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 1.62 Å R-free 0.252 |
| 4QYP The Crystal Structures of holo-wt human Cellular Retinol Binding protein II (hCRBPII) bound to Retinal Deposited 2014-07-25 | Different construct Different mutation/modification Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain D
2–134（133 aa）
Fragment：transfer protein
|
Not recorded | ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 1.62 Å R-free 0.252 |
| 4QZT Crystal Structure of wild type Human Cellular Retinol Binding Protein II (hCRBPII) bound to retinol at 7 KeV beam energy Deposited 2014-07-28 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | RTL RETINOL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.90 Å R-free 0.244 |
| 4QZT Crystal Structure of wild type Human Cellular Retinol Binding Protein II (hCRBPII) bound to retinol at 7 KeV beam energy Deposited 2014-07-28 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
|
Not recorded | RTL RETINOL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.90 Å R-free 0.244 |
| 4QZT Crystal Structure of wild type Human Cellular Retinol Binding Protein II (hCRBPII) bound to retinol at 7 KeV beam energy Deposited 2014-07-28 | Different mutation/modification Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Not recorded | ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.90 Å R-free 0.244 |
| 4QZT Crystal Structure of wild type Human Cellular Retinol Binding Protein II (hCRBPII) bound to retinol at 7 KeV beam energy Deposited 2014-07-28 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain D
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.90 Å R-free 0.244 |
| 4QZU Crystal Structure of wild type Human Cellular Retinol Binding Protein II (hCRBPII) bound to retinol at 11 KeV beam energy Deposited 2014-07-28 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | RTL RETINOL × 1 ACT ACETATE ION × 1 GOL GLYCEROL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.50 Å R-free 0.218 |
| 4QZU Crystal Structure of wild type Human Cellular Retinol Binding Protein II (hCRBPII) bound to retinol at 11 KeV beam energy Deposited 2014-07-28 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
|
Not recorded | RTL RETINOL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.50 Å R-free 0.218 |
| 4QZU Crystal Structure of wild type Human Cellular Retinol Binding Protein II (hCRBPII) bound to retinol at 11 KeV beam energy Deposited 2014-07-28 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Not recorded | RTL RETINOL × 1 ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.50 Å R-free 0.218 |
| 4QZU Crystal Structure of wild type Human Cellular Retinol Binding Protein II (hCRBPII) bound to retinol at 11 KeV beam energy Deposited 2014-07-28 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain D
2–134（133 aa）
|
Not recorded | ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.50 Å R-free 0.218 |
| 4RUU Crystal structure of the Q108K:K40L mutant of human Cellular Retinol Binding ProteinII in complex with All-trans-Retinal after 24 hour incubation at 1.4 Angstrom Resolution Deposited 2014-11-21 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：K40L, Q108K | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；298 K；30 % PEG 4000, 0.1 M Ammonium Acatate, 0.1 M Sodium Acetate pH 4.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.40 Å R-free 0.238 |
| 4RUU Crystal structure of the Q108K:K40L mutant of human Cellular Retinol Binding ProteinII in complex with All-trans-Retinal after 24 hour incubation at 1.4 Angstrom Resolution Deposited 2014-11-21 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：K40L, Q108K | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；298 K；30 % PEG 4000, 0.1 M Ammonium Acatate, 0.1 M Sodium Acetate pH 4.0, VAPOR DIFFUSION, HANGING DROP, temperature 298K
|
Resolution 1.40 Å R-free 0.238 |
| 4ZCB Human CRBPII mutant - Y60W dimer Deposited 2015-04-15 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Fragment：UNP residues 2-134
Chain B
2–134（133 aa）
Fragment：UNP residues 2-134
|
Mutation：Y60W Mutation：Y60W | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；294 K；30% PEG 4000, 0.1M CH3COONa.3H2O, pH 4.6, 0.1M CH3COONH4
|
Resolution 1.70 Å R-free 0.239 |
| 4ZGU Crystal structure of monomer Y60W hCRBPII Deposited 2015-04-24 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Y60W | ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；294.15 K；30% PEG 4000, 0.1M CH3COONa.3H2O pH4.6, 0.1M CH3COONH4
|
Resolution 1.49 Å R-free 0.246 |
| 4ZGU Crystal structure of monomer Y60W hCRBPII Deposited 2015-04-24 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Y60W | ACT ACETATE ION × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；294.15 K；30% PEG 4000, 0.1M CH3COONa.3H2O pH4.6, 0.1M CH3COONH4
|
Resolution 1.49 Å R-free 0.246 |
| 4ZGU Crystal structure of monomer Y60W hCRBPII Deposited 2015-04-24 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
|
Mutation：Y60W | ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；294.15 K；30% PEG 4000, 0.1M CH3COONa.3H2O pH4.6, 0.1M CH3COONH4
|
Resolution 1.49 Å R-free 0.246 |
| 4ZGU Crystal structure of monomer Y60W hCRBPII Deposited 2015-04-24 | Different mutation/modification Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain D
2–134（133 aa）
|
Mutation：Y60W | ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；294.15 K；30% PEG 4000, 0.1M CH3COONa.3H2O pH4.6, 0.1M CH3COONH4
|
Resolution 1.49 Å R-free 0.246 |
| 4ZH6 Crystal Structure of the Domain-Swapped Dimer Y60L mutant of Human Cellular Retinol Binding Protein II Deposited 2015-04-24 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
|
Mutation：Y60L | ACT ACETATE ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M
|
Resolution 1.55 Å R-free 0.224 |
| 4ZH9 Crystal Structure of the Domain-Swapped Dimer Wild-Type of Human Cellular Retinol Binding Protein II Deposited 2015-04-24 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M
|
Resolution 2.66 Å R-free 0.274 |
| 4ZJ0 The crystal structure of monomer Q108K:K40L:Y60W CRBPII bound to all-trans-retinal Deposited 2015-04-28 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
Fragment：UNP residues 2-134
|
Mutation：K40L, Y60W, Q108K | ACT ACETATE ION × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；294 K；30% PEG4000, 0.1M CH3COONa.3H2O, pH 4.6, 0.1M CH3COONH4
|
Resolution 1.50 Å R-free 0.251 |
| 4ZJ0 The crystal structure of monomer Q108K:K40L:Y60W CRBPII bound to all-trans-retinal Deposited 2015-04-28 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
Fragment：UNP residues 2-134
|
Mutation：K40L, Y60W, Q108K | ACT ACETATE ION × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；294 K；30% PEG4000, 0.1M CH3COONa.3H2O, pH 4.6, 0.1M CH3COONH4
|
Resolution 1.50 Å R-free 0.251 |
| 4ZR2 Crystal Structure of the Domain-Swapped Dimer K40L:Q108K:Y60W mutant of Human Cellular Retinol Binding Protein II Deposited 2015-05-11 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：Q108K, K40L, Y60W Mutation：Q108K, K40L, Y60W | RET RETINAL × 1 ACT ACETATE ION × 5 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；25% PEG 4000 (40%), 0.1M Sodium Acetate pH 4.5, Ammonium Acetate 0.1M
|
Resolution 1.80 Å R-free 0.218 |
| 5DG4 Crystal structure of monomer human cellular retinol binding protein II-Y60L Deposited 2015-08-27 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Y60L | ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 1.50 Å R-free 0.243 |
| 5DG4 Crystal structure of monomer human cellular retinol binding protein II-Y60L Deposited 2015-08-27 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Y60L | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 1.50 Å R-free 0.243 |
| 5DG4 Crystal structure of monomer human cellular retinol binding protein II-Y60L Deposited 2015-08-27 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
|
Mutation：Y60L | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 1.50 Å R-free 0.243 |
| 5DG4 Crystal structure of monomer human cellular retinol binding protein II-Y60L Deposited 2015-08-27 | Different mutation/modification Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain D
2–134（133 aa）
|
Mutation：Y60L | ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 1.50 Å R-free 0.243 |
| 5DPQ Crystal Structure of E72A mutant of domain swapped dimer Human Cellular Retinol Binding Protein Deposited 2015-09-14 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：E72A Mutation：E72A | ACT ACETATE ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6, EVAPORATION, temperature 298K
|
Resolution 1.77 Å R-free 0.220 |
| 5F58 Crystal structure of the Q108K:K40L:T51V:R58F mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.54 Angstrom Resolution Deposited 2015-12-04 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V, R58F | RET RETINAL × 1 ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1M Ammonium Acetate, 0.1M Sodium Acetate pH = 4.5
|
Resolution 1.54 Å R-free 0.229 |
| 5F58 Crystal structure of the Q108K:K40L:T51V:R58F mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.54 Angstrom Resolution Deposited 2015-12-04 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V, R58F | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1M Ammonium Acetate, 0.1M Sodium Acetate pH = 4.5
|
Resolution 1.54 Å R-free 0.229 |
| 5F6B Crystal structure of the Q108K:K40L:T51V:R58Y:Y19W mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.3 Angstrom Resolution Deposited 2015-12-05 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V, R58Y, Y19W | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；25 %PEG 4000, 0.1 M Ammonium Acetate, 0.1 M Sodium Acetate pH = 4.5.
|
Resolution 1.31 Å R-free 0.235 |
| 5F6B Crystal structure of the Q108K:K40L:T51V:R58Y:Y19W mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.3 Angstrom Resolution Deposited 2015-12-05 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V, R58Y, Y19W | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；25 %PEG 4000, 0.1 M Ammonium Acetate, 0.1 M Sodium Acetate pH = 4.5.
|
Resolution 1.31 Å R-free 0.235 |
| 5F7G Crystal structure of the Q108K:K40L:T51V:R58Y:Y19W:Q38L mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.48 Angstrom Resolution Deposited 2015-12-08 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V, R58Y, Y19W, Q38L | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；25% PEG 4000, 0.1 M Ammonium Acetate, 0.1 M sodium acetate pH = 4.5
|
Resolution 1.48 Å R-free 0.252 |
| 5F7G Crystal structure of the Q108K:K40L:T51V:R58Y:Y19W:Q38L mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.48 Angstrom Resolution Deposited 2015-12-08 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V, R58Y, Y19W, Q38L | RET RETINAL × 1 ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；25% PEG 4000, 0.1 M Ammonium Acetate, 0.1 M sodium acetate pH = 4.5
|
Resolution 1.48 Å R-free 0.252 |
| 5FAZ Crystal structure of the Q108K:K40L:T51V mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.4 Angstrom Resolution Deposited 2015-12-13 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V | ACT ACETATE ION × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30 % PEG 4000, 0.1M Ammonium Acetate, 0.1M Sodium acetate pH = 4.5
|
Resolution 1.40 Å R-free 0.255 |
| 5FAZ Crystal structure of the Q108K:K40L:T51V mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.4 Angstrom Resolution Deposited 2015-12-13 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V | ACT ACETATE ION × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30 % PEG 4000, 0.1M Ammonium Acetate, 0.1M Sodium acetate pH = 4.5
|
Resolution 1.40 Å R-free 0.255 |
| 5FEN Crystal structure of the Q108K:K40L:T53C mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.55 Angstrom Resolution Deposited 2015-12-17 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T53C | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG4000, 0.1M Ammonium Acetate, 0.1 M Sodium Acetate pH 4.5
|
Resolution 1.55 Å R-free 0.241 |
| 5FEN Crystal structure of the Q108K:K40L:T53C mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal after 24 hours of incubation at 1.55 Angstrom Resolution Deposited 2015-12-17 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K, K40L, T53C | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG4000, 0.1M Ammonium Acetate, 0.1 M Sodium Acetate pH 4.5
|
Resolution 1.55 Å R-free 0.241 |
| 5FFH Crystal structure of the Q108K:K40L:T51V:R58W:Y19W mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.68 Angstrom Resolution Deposited 2015-12-18 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V, R58W, Y19W | ACT ACETATE ION × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；25% PEG4000, 0.1M Ammonium Acetate, 0.1M Sodium Acetate
|
Resolution 1.68 Å R-free 0.267 |
| 5FFH Crystal structure of the Q108K:K40L:T51V:R58W:Y19W mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.68 Angstrom Resolution Deposited 2015-12-18 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K, K40L, T51V, R58W, Y19W | ACT ACETATE ION × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；25% PEG4000, 0.1M Ammonium Acetate, 0.1M Sodium Acetate
|
Resolution 1.68 Å R-free 0.267 |
| 5U6G Crystal Structure of the holo Domain-Swapped Dimer mutant Q108K:K40D Human Cellular Retinol Binding Protein II bound with all trans retinal Deposited 2016-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain F
2–134（133 aa）
|
Mutation：Q108K, K40D Mutation：Q108K, K40D | RET RETINAL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 2.60 Å R-free 0.281 |
| 5U6G Crystal Structure of the holo Domain-Swapped Dimer mutant Q108K:K40D Human Cellular Retinol Binding Protein II bound with all trans retinal Deposited 2016-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain B
2–134（133 aa）
Chain E
2–134（133 aa）
|
Mutation：Q108K, K40D Mutation：Q108K, K40D | RET RETINAL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 2.60 Å R-free 0.281 |
| 5U6G Crystal Structure of the holo Domain-Swapped Dimer mutant Q108K:K40D Human Cellular Retinol Binding Protein II bound with all trans retinal Deposited 2016-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain C
2–134（133 aa）
Chain G
2–134（133 aa）
|
Mutation：Q108K, K40D Mutation：Q108K | RET RETINAL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 2.60 Å R-free 0.281 |
| 5U6G Crystal Structure of the holo Domain-Swapped Dimer mutant Q108K:K40D Human Cellular Retinol Binding Protein II bound with all trans retinal Deposited 2016-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain D
2–134（133 aa）
Chain H
2–134（133 aa）
|
Mutation：Q108K, K40D Mutation：Q108K, K40D | RET RETINAL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 2.60 Å R-free 0.281 |
| 5U6G Crystal Structure of the holo Domain-Swapped Dimer mutant Q108K:K40D Human Cellular Retinol Binding Protein II bound with all trans retinal Deposited 2016-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain I
2–134（133 aa）
Chain K
2–134（133 aa）
|
Mutation：Q108K Mutation：Q108K, K40D | RET RETINAL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 2.60 Å R-free 0.281 |
| 5U6G Crystal Structure of the holo Domain-Swapped Dimer mutant Q108K:K40D Human Cellular Retinol Binding Protein II bound with all trans retinal Deposited 2016-12-08 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain J
2–134（133 aa）
Chain L
2–134（133 aa）
|
Mutation：Q108K, K40D Mutation：Q108K, K40D | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6
|
Resolution 2.60 Å R-free 0.281 |
| 6BTH Crystal structure of human cellular retinol binding protein 2 (CRBP2) in complex with 2-arachidonoylglycerol (2-AG) Deposited 2017-12-06 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–134（134 aa）
|
Not recorded | ECB 1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate × 1 PEG DI(HYDROXYETHYL)ETHER × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；295 K；0.1 M Tris HCl, PEG 3350 22-28%
|
Resolution 1.35 Å R-free 0.164 |
| 6BTH Crystal structure of human cellular retinol binding protein 2 (CRBP2) in complex with 2-arachidonoylglycerol (2-AG) Deposited 2017-12-06 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
1–134（134 aa）
|
Not recorded | ECB 1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；295 K；0.1 M Tris HCl, PEG 3350 22-28%
|
Resolution 1.35 Å R-free 0.164 |
| 6BTI Crystal structure of human cellular retinol binding protein 2 (CRBP2) in complex with N-arachidonoylethanolamine (AEA) Deposited 2017-12-06 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–134（134 aa）
|
Not recorded | E7Y (5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-tetraenamide × 1 PEG DI(HYDROXYETHYL)ETHER × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.1 M TrisHCl, PEG 3350 22-28%.
|
Resolution 1.45 Å R-free 0.185 |
| 6BTI Crystal structure of human cellular retinol binding protein 2 (CRBP2) in complex with N-arachidonoylethanolamine (AEA) Deposited 2017-12-06 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
1–134（134 aa）
|
Not recorded | E7Y (5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-tetraenamide × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；293 K；0.1 M TrisHCl, PEG 3350 22-28%.
|
Resolution 1.45 Å R-free 0.185 |
| 6C7Z Crystal structure of the Q108K:K40L:T51V:R58F mutant of human Cellular Retinol Binding Protein II in complex with synthetic Ligand Julolidine Deposited 2018-01-23 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K,K40L,T51V,R58F | ACT ACETATE ION × 1 JLO (2E,4E)-3-methyl-5-(2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-yl)penta-2,4-dienal × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1M Ammonium Acetate, 0.1 M Sodium Acetate pH=4.5
|
Resolution 1.42 Å R-free 0.256 |
| 6C7Z Crystal structure of the Q108K:K40L:T51V:R58F mutant of human Cellular Retinol Binding Protein II in complex with synthetic Ligand Julolidine Deposited 2018-01-23 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K,K40L,T51V,R58F | ACT ACETATE ION × 1 JLO (2E,4E)-3-methyl-5-(2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-yl)penta-2,4-dienal × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.5；298 K；30% PEG 4000, 0.1M Ammonium Acetate, 0.1 M Sodium Acetate pH=4.5
|
Resolution 1.42 Å R-free 0.256 |
| 6E50 Crystal structure of the apo domain-swapped dimer Q108K:K40L:T51F mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-18 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51F | ACT ACETATE ION × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；298 K；PEG 4000, sodium acetate, Ammonium acetate
|
Resolution 1.97 Å R-free 0.266 |
| 6E51 Crystal structure of the apo domain-swapped dimer Q108K:K40L:T51W mutant of human cellular retinol binding protein II Deposited 2018-07-19 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51W | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, ammonium acetate, Sodium acetate
|
Resolution 2.26 Å R-free 0.287 |
| 6E5E Crystal structure of the apo domain-swapped dimer Q108K:T51D mutant of human cellular retinol binding protein II Deposited 2018-07-20 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, T51D | ACT ACETATE ION × 8 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；4000 PEG, sodium acetate, ammonium acetate
|
Resolution 1.70 Å R-free 0.242 |
| 6E5Q Crystal structure of the apo domain-swapped dimer Q108K:T51D:A28H mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-21 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, T51D, A28H | ACT ACETATE ION × 8 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, ammonium acetete
|
Resolution 1.99 Å R-free 0.267 |
| 6E5R Crystal structure of the apo domain-swapped dimer Q108K:T51D:A28C mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：Q108K, A28C, T51D Mutation：Q108K, A28C, T51D | ACT ACETATE ION × 3 GOL GLYCEROL × 5 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, ammonium acetate, sodium acetate
|
Resolution 2.59 Å R-free 0.281 |
| 6E5S Crystal structure of holo retinal-bound domain-swapped dimer Q108K:T51D mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain C
2–134（133 aa）
|
Mutation：Q108K, T51D Mutation：Q108K, T51D | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, Ammonium acetate
|
Resolution 2.06 Å R-free 0.274 |
| 6E5S Crystal structure of holo retinal-bound domain-swapped dimer Q108K:T51D mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain B
2–134（133 aa）
Chain J
2–134（133 aa）
|
Mutation：Q108K, T51D Mutation：Q108K, T51D | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, Ammonium acetate
|
Resolution 2.06 Å R-free 0.274 |
| 6E5S Crystal structure of holo retinal-bound domain-swapped dimer Q108K:T51D mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain D
2–134（133 aa）
Chain K
2–134（133 aa）
|
Mutation：Q108K, T51D Mutation：Q108K, T51D | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, Ammonium acetate
|
Resolution 2.06 Å R-free 0.274 |
| 6E5S Crystal structure of holo retinal-bound domain-swapped dimer Q108K:T51D mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain E
2–134（133 aa）
Chain L
2–134（133 aa）
|
Mutation：Q108K, T51D Mutation：Q108K, T51D | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, Ammonium acetate
|
Resolution 2.06 Å R-free 0.274 |
| 6E5S Crystal structure of holo retinal-bound domain-swapped dimer Q108K:T51D mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain F
2–134（133 aa）
Chain H
2–134（133 aa）
|
Mutation：Q108K, T51D Mutation：Q108K, T51D | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, Ammonium acetate
|
Resolution 2.06 Å R-free 0.274 |
| 6E5S Crystal structure of holo retinal-bound domain-swapped dimer Q108K:T51D mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain G
2–134（133 aa）
Chain I
2–134（133 aa）
|
Mutation：Q108K, T51D Mutation：Q108K, T51D | RET RETINAL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, Ammonium acetate
|
Resolution 2.06 Å R-free 0.274 |
| 6E6L Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:K40L:T51F:Y60A mutant of human cellular retinol binding protein II Deposited 2018-07-25 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51F, Y60A | ACT ACETATE ION × 2 RET RETINAL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, Ammonium acetate
|
Resolution 2.08 Å R-free 0.248 |
| 6E7M Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28C mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain C
2–134（133 aa）
|
Mutation：Q108K, T51D, A28C Mutation：Q108K, T51D, A28C | ACT ACETATE ION × 8 GOL GLYCEROL × 4 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, ammonium acetate, sodium acetate
|
Resolution 2.70 Å R-free 0.296 |
| 6E7M Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28C mutant of human Cellular Retinol Binding Protein II Deposited 2018-07-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain B
2–134（133 aa）
Chain D
2–134（133 aa）
|
Mutation：Q108K, T51D, A28C Mutation：Q108K, T51D, A28C | ACT ACETATE ION × 2 GOL GLYCEROL × 2 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, ammonium acetate, sodium acetate
|
Resolution 2.70 Å R-free 0.296 |
| 6MCU Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28H mutant of human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain D
2–134（133 aa）
|
Mutation：Q108K, T51D, A28H Mutation：Q108K, T51D, A28H | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；298 K；PEG 4000, ammonium sulfate, sodium acetate
|
Resolution 2.57 Å R-free 0.296 |
| 6MCU Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28H mutant of human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain B
2–134（133 aa）
Chain C
2–134（133 aa）
|
Mutation：Q108K, T51D, A28H Mutation：Q108K, T51D, A28H | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；298 K；PEG 4000, ammonium sulfate, sodium acetate
|
Resolution 2.57 Å R-free 0.296 |
| 6MCU Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28H mutant of human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain E
2–134（133 aa）
Chain H
2–134（133 aa）
|
Mutation：Q108K, T51D, A28H Mutation：Q108K, T51D, A28H | GOL GLYCEROL × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；298 K；PEG 4000, ammonium sulfate, sodium acetate
|
Resolution 2.57 Å R-free 0.296 |
| 6MCU Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28H mutant of human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain F
2–134（133 aa）
Chain G
2–134（133 aa）
|
Mutation：Q108K, T51D, A28H Mutation：Q108K, T51D, A28H | GOL GLYCEROL × 1 RET RETINAL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；298 K；PEG 4000, ammonium sulfate, sodium acetate
|
Resolution 2.57 Å R-free 0.296 |
| 6MCU Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28H mutant of human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain I
2–134（133 aa）
Chain L
2–134（133 aa）
|
Mutation：Q108K, T51D, A28H Mutation：Q108K, T51D, A28H | GOL GLYCEROL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；298 K；PEG 4000, ammonium sulfate, sodium acetate
|
Resolution 2.57 Å R-free 0.296 |
| 6MCU Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28H mutant of human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain J
2–134（133 aa）
Chain K
2–134（133 aa）
|
Mutation：Q108K, T51D, A28H Mutation：Q108K, T51D, A28H | RET RETINAL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；298 K；PEG 4000, ammonium sulfate, sodium acetate
|
Resolution 2.57 Å R-free 0.296 |
| 6MCV Crystal Structure of Holo Retinal-Bound Domain-Swapped Dimer of Wild Type Human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain K
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；298 K；4000 PEG, Ammonium acetate, Sodium acetate
|
Resolution 3.30 Å R-free 0.266 |
| 6MCV Crystal Structure of Holo Retinal-Bound Domain-Swapped Dimer of Wild Type Human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain B
2–134（133 aa）
Chain L
2–134（133 aa）
|
Not recorded | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；298 K；4000 PEG, Ammonium acetate, Sodium acetate
|
Resolution 3.30 Å R-free 0.266 |
| 6MCV Crystal Structure of Holo Retinal-Bound Domain-Swapped Dimer of Wild Type Human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain C
2–134（133 aa）
Chain G
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；298 K；4000 PEG, Ammonium acetate, Sodium acetate
|
Resolution 3.30 Å R-free 0.266 |
| 6MCV Crystal Structure of Holo Retinal-Bound Domain-Swapped Dimer of Wild Type Human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain D
2–134（133 aa）
Chain H
2–134（133 aa）
|
Not recorded | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；298 K；4000 PEG, Ammonium acetate, Sodium acetate
|
Resolution 3.30 Å R-free 0.266 |
| 6MCV Crystal Structure of Holo Retinal-Bound Domain-Swapped Dimer of Wild Type Human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 5 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain E
2–134（133 aa）
Chain I
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；298 K；4000 PEG, Ammonium acetate, Sodium acetate
|
Resolution 3.30 Å R-free 0.266 |
| 6MCV Crystal Structure of Holo Retinal-Bound Domain-Swapped Dimer of Wild Type Human Cellular Retinol Binding Protein II Deposited 2018-09-02 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 6 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain F
2–134（133 aa）
Chain J
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
EVAPORATION；298 K；4000 PEG, Ammonium acetate, Sodium acetate
|
Resolution 3.30 Å R-free 0.266 |
| 6MKV Crystal structure of Retinal-bound holo Q108K:K40L:T51W domain-swapped dimer of human cellular retinol binding protein 2 Deposited 2018-09-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain C
2–134（133 aa）
|
Mutation：Q108K,K40L,T51W Mutation：Q108K,K40L,T51W | RET RETINAL × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；PEG 4000, Sodium acetate, Ammonium acetate
|
Resolution 2.11 Å R-free 0.273 |
| 6MKV Crystal structure of Retinal-bound holo Q108K:K40L:T51W domain-swapped dimer of human cellular retinol binding protein 2 Deposited 2018-09-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain B
2–134（133 aa）
Chain D
2–134（133 aa）
|
Mutation：Q108K,K40L,T51W Mutation：Q108K,K40L,T51W | RET RETINAL × 2 ACT ACETATE ION × 6 GOL GLYCEROL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；293 K；PEG 4000, Sodium acetate, Ammonium acetate
|
Resolution 2.11 Å R-free 0.273 |
| 6MLB Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:K40L:T51F mutant of human cellular retinol binding protein II Deposited 2018-09-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Fragment：Q108K, K40L, T51F
Chain C
2–134（133 aa）
Fragment：Q108K, K40L, T51F
|
Not recorded | GOL GLYCEROL × 1 ACT ACETATE ION × 2 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, ammonium acetate, sodium acetate
|
Resolution 2.15 Å R-free 0.302 |
| 6MLB Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:K40L:T51F mutant of human cellular retinol binding protein II Deposited 2018-09-27 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain B
2–134（133 aa）
Fragment：Q108K, K40L, T51F
Chain D
2–134（133 aa）
Fragment：Q108K, K40L, T51F
|
Not recorded | GOL GLYCEROL × 3 ACT ACETATE ION × 3 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, ammonium acetate, sodium acetate
|
Resolution 2.15 Å R-free 0.302 |
| 6ON5 Crystal Structure of the Zn-bound Domain-Swapped Dimer Q108K:T51D:A28C:L36C:F57H Mutant of Human Cellular Retinol Binding Protein II Deposited 2019-04-20 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：Q108K,T51D,A28C,L36C,F57H Mutation：Q108K,T51D,A28C,L36C,F57H | ZN ZINC ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 3350, Bis-Tris-HCl
|
Resolution 1.64 Å R-free 0.255 |
| 6ON7 Crystal Structure of Apo Domain-Swapped Dimer Q108K:T51D:A28C:L36C Mutant of Human Cellular Retinol Binding Protein II Deposited 2019-04-20 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：Q108K,T51D,A28C,L36C Mutation：Q108K,T51D,A28C,L36C | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate
|
Resolution 1.98 Å R-free 0.254 |
| 6ON8 Crystal Structure of the Reduced Form of Apo Domain-Swapped Dimer Q108K:T51D:A28C:L36C:F57H Mutant of Human Cellular Retinol Binding Protein II Deposited 2019-04-20 | Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K,T51D,A28C,L36C,F57H | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；Bis-Tris:HCl, PEG 3350
|
Resolution 2.40 Å R-free 0.258 |
| 6VID The Crystal Structure of Aps Domain-Swapped Trimer Q108K:K40D:T53A:R58L:Q38F:Q4F Variant of HCRBPII Deposited 2020-01-12 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
Chain D
2–134（133 aa）
|
Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F | ACT ACETATE ION × 3 GOL GLYCEROL × 5 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, Sodium acetate, Ammonium acetate
|
Resolution 2.89 Å R-free 0.308 |
| 6VID The Crystal Structure of Aps Domain-Swapped Trimer Q108K:K40D:T53A:R58L:Q38F:Q4F Variant of HCRBPII Deposited 2020-01-12 | Different construct Different mutation/modification Different oligomeric state Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain C
2–134（133 aa）
Chain E
2–134（133 aa）
Chain F
2–134（133 aa）
|
Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F | ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, Sodium acetate, Ammonium acetate
|
Resolution 2.89 Å R-free 0.308 |
| 6VIS The Crystal Structure of Domain-Swapped Trimer Q108K:K40D:T53A:R58L:Q38F:Q4F:V62E Variant of HCRBPII Deposited 2020-01-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
Chain C
2–134（133 aa）
|
Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F, V62E Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F, V62E Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F, V62E | GOL GLYCEROL × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；293 K；PEG 4000, Sodium acetate, ammonium acetate
|
Resolution 2.79 Å R-free 0.298 |
| 6VIT The Crystal Structure of Apo Domain-Swapped dimer Q108K:T51D:I32C Variant of HCRBPII with an Engineered Disulfide Bond Deposited 2020-01-13 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：Q108K, T51D, I32C Mutation：Q108K, T51D, I32C | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 6.4；298 K；citric acid, PEG 3350
|
Resolution 3.20 Å R-free 0.288 |
| 6WNF The Crystal Structure of Apo Domain-Swapped Dimer Q108K:K40D:T53A:R58L:Q38F:Q4F:F57H Variant of HCRBPII Deposited 2020-04-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：Q108K,K40D,T53A,R58L,Q38F,Q4F,F57H Mutation：Q108K,K40D,T53A,R58L,Q38F,Q4F,F57H | ACT ACETATE ION × 3 GOL GLYCEROL × 6 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, Sodium acetate, ammonium acetate
|
Resolution 1.67 Å R-free 0.270 |
| 6WNJ The Crystal Structure of Apo Domain-Swapped Trimer Q108K:T51D:A28C:I32C of HCRBPII Deposited 2020-04-22 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
Chain C
2–134（133 aa）
|
Mutation：Q108K,T51D,A28C,I32C Mutation：Q108K,T51D,A28C,I32C Mutation：Q108K,T51D,A28C,I32C | GOL GLYCEROL × 7 144 TRIS-HYDROXYMETHYL-METHYL-AMMONIUM × 3 SO4 SULFATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4.6；298 K；sodium acetate trihydrate, ammonium sulfate
|
Resolution 2.10 Å R-free 0.239 |
| 6WP0 The Crystal Structure of Domain-Swapped Trimer Q108K:T51D variant of HCRBPII Deposited 2020-04-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain A
2–134（133 aa）
Chain I
2–134（133 aa）
Chain K
2–134（133 aa）
|
Mutation：Q108K, T51D Mutation：Q108K, T51D Mutation：Q108K, T51D | GOL GLYCEROL × 6 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；sodium acetate, ammonium acetate, PEG 4000
|
Resolution 2.78 Å R-free 0.321 |
| 6WP0 The Crystal Structure of Domain-Swapped Trimer Q108K:T51D variant of HCRBPII Deposited 2020-04-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain B
2–134（133 aa）
Chain J
2–134（133 aa）
Chain L
2–134（133 aa）
|
Mutation：Q108K, T51D Mutation：Q108K, T51D Mutation：Q108K, T51D | GOL GLYCEROL × 10 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；sodium acetate, ammonium acetate, PEG 4000
|
Resolution 2.78 Å R-free 0.321 |
| 6WP0 The Crystal Structure of Domain-Swapped Trimer Q108K:T51D variant of HCRBPII Deposited 2020-04-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain C
2–134（133 aa）
Chain E
2–134（133 aa）
Chain G
2–134（133 aa）
|
Mutation：Q108K, T51D Mutation：Q108K, T51D Mutation：Q108K, T51D | GOL GLYCEROL × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；sodium acetate, ammonium acetate, PEG 4000
|
Resolution 2.78 Å R-free 0.321 |
| 6WP0 The Crystal Structure of Domain-Swapped Trimer Q108K:T51D variant of HCRBPII Deposited 2020-04-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain D
2–134（133 aa）
Chain F
2–134（133 aa）
Chain H
2–134（133 aa）
|
Mutation：Q108K, T51D Mutation：Q108K, T51D Mutation：Q108K, T51D | GOL GLYCEROL × 2 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；sodium acetate, ammonium acetate, PEG 4000
|
Resolution 2.78 Å R-free 0.321 |
| 6WP1 The Crystal Structure of Apo Domain-Swapped Trimer Q108K:K40L:T51K Variant of HCRBPII Deposited 2020-04-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain A
2–134（133 aa）
Chain E
2–134（133 aa）
Chain F
2–134（133 aa）
|
Mutation：Q108K, K40L, T51K Mutation：Q108K, K40L, T51K Mutation：Q108K, K40L, T51K | ACT ACETATE ION × 1 GOL GLYCEROL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, sodium acetate, ammonium acetate
|
Resolution 2.99 Å R-free 0.302 |
| 6WP1 The Crystal Structure of Apo Domain-Swapped Trimer Q108K:K40L:T51K Variant of HCRBPII Deposited 2020-04-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain B
2–134（133 aa）
Chain C
2–134（133 aa）
Chain D
2–134（133 aa）
|
Mutation：Q108K, K40L, T51K Mutation：Q108K, K40L, T51K Mutation：Q108K, K40L, T51K | ACT ACETATE ION × 4 GOL GLYCEROL × 7 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, sodium acetate, ammonium acetate
|
Resolution 2.99 Å R-free 0.302 |
| 6WP2 The Crystal Structure of Apo Zinc-Bound Domain Swapped-Trimer Q108K:K40D:T53A:R58L:Q38F:Q4F:F57H Variant of HCRBPII Deposited 2020-04-26 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
Chain C
2–134（133 aa）
|
Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F, F57H Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F, F57H Mutation：Q108K, K40D, T53A, R58L, Q38F, Q4F, F57H | ZN ZINC ION × 6 GOL GLYCEROL × 5 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；ammonium iodide, PEG 3350
|
Resolution 2.48 Å R-free 0.312 |
| 7JVG Cellular retinol-binding protein 2 (CRBP2) in complex with 1-arachidonoylglycerol Deposited 2020-08-21 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–134（134 aa）
|
Not recorded | 1AG (2S)-2,3-dihydroxypropyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；298 K；0.1 M Tris/HCl, pH 8.0, PEG 3350 25%
|
Resolution 1.40 Å R-free 0.196 |
| 7JVG Cellular retinol-binding protein 2 (CRBP2) in complex with 1-arachidonoylglycerol Deposited 2020-08-21 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
1–134（134 aa）
|
Not recorded | 1AG (2S)-2,3-dihydroxypropyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；298 K；0.1 M Tris/HCl, pH 8.0, PEG 3350 25%
|
Resolution 1.40 Å R-free 0.196 |
| 7JVY Cellular retinol-binding protein 2 (CRBP2) in complex with 2-arachidonylglyceryl ether Deposited 2020-08-24 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–134（134 aa）
|
Not recorded | VKV 2-{[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraen-1-yl]oxy}propane-1,3-diol × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；298 K；0.1 M Tris/HCl, PEG 3350 25%
|
Resolution 1.30 Å R-free 0.166 |
| 7JVY Cellular retinol-binding protein 2 (CRBP2) in complex with 2-arachidonylglyceryl ether Deposited 2020-08-24 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
1–134（134 aa）
|
Not recorded | VKV 2-{[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraen-1-yl]oxy}propane-1,3-diol × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；298 K；0.1 M Tris/HCl, PEG 3350 25%
|
Resolution 1.30 Å R-free 0.166 |
| 7JWD Cellular retinol-binding protein 2 (CRBP2) in complex with 2-linoleoylglycerol Deposited 2020-08-25 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–134（134 aa）
|
Not recorded | VL7 1,3-dihydroxypropan-2-yl (9Z,12Z)-octadeca-9,12-dienoate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.1 M Tris HCl, PEG 3350 22-28%
|
Resolution 1.35 Å R-free 0.148 |
| 7JWD Cellular retinol-binding protein 2 (CRBP2) in complex with 2-linoleoylglycerol Deposited 2020-08-25 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
1–134（134 aa）
|
Not recorded | VL7 1,3-dihydroxypropan-2-yl (9Z,12Z)-octadeca-9,12-dienoate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.1 M Tris HCl, PEG 3350 22-28%
|
Resolution 1.35 Å R-free 0.148 |
| 7JWR Cellular retinol-binding protein 2 (CRBP2) in complex with 2-oleoylglycerol Deposited 2020-08-26 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–134（134 aa）
|
Not recorded | YOG 1,3-dihydroxypropan-2-yl (9Z)-octadec-9-enoate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.1 M Tris HCl, PEG 3350 22-28%
|
Resolution 1.30 Å R-free 0.174 |
| 7JWR Cellular retinol-binding protein 2 (CRBP2) in complex with 2-oleoylglycerol Deposited 2020-08-26 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
1–134（134 aa）
|
Not recorded | YOG 1,3-dihydroxypropan-2-yl (9Z)-octadec-9-enoate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.1 M Tris HCl, PEG 3350 22-28%
|
Resolution 1.30 Å R-free 0.174 |
| 7JX2 Cellular retinol-binding protein 2 (CRBP2) in complex with 2-palmitoylglycerol Deposited 2020-08-26 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–134（134 aa）
|
Not recorded | VLP 1,3-dihydroxypropan-2-yl hexadecanoate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.1 M Tris HCl, PEG 3350 22-28%
|
Resolution 1.80 Å R-free 0.256 |
| 7JZ5 Cellular retinol-binding protein 2 (CRBP2) in complex with 1-arachodonoyl-1-thio-glycerol Deposited 2020-09-01 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–134（134 aa）
|
Not recorded | VPY S-[(2R)-2,3-dihydroxypropyl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenethioate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.1 M Tris HCl, PEG 3350 22-28%
|
Resolution 1.57 Å R-free 0.183 |
| 7JZ5 Cellular retinol-binding protein 2 (CRBP2) in complex with 1-arachodonoyl-1-thio-glycerol Deposited 2020-09-01 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
1–134（134 aa）
|
Not recorded | VPY S-[(2R)-2,3-dihydroxypropyl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenethioate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；0.1 M Tris HCl, PEG 3350 22-28%
|
Resolution 1.57 Å R-free 0.183 |
| 7K3I Cellular retinol-binding protein 2 (CRBP2) in complex with 2-lauroylglycerol Deposited 2020-09-11 | Different construct Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
1–134（134 aa）
|
Not recorded | VLZ 1,3-dihydroxypropan-2-yl dodecanoate × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, SITTING DROP；pH 8；293 K；Tris/HCl Ph 8.0, PEG3350 20%-25%
|
Resolution 1.20 Å R-free 0.206 |
| 7LHM Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A:Q38L mutant of cellular retinol binding protein II complex with all-trans-retinal Deposited 2021-01-25 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K,K40L,T51V,T53C,R58W,T29L,Y19W,Q4A,Q38L | ACT ACETATE ION × 1 RET RETINAL × 1 GOL GLYCEROL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 1.50 Å R-free 0.222 |
| 7LHM Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A:Q38L mutant of cellular retinol binding protein II complex with all-trans-retinal Deposited 2021-01-25 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K,K40L,T51V,T53C,R58W,T29L,Y19W,Q4A,Q38L | ACT ACETATE ION × 1 RET RETINAL × 1 GOL GLYCEROL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 1.50 Å R-free 0.222 |
| 7LHN Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal after exposure to visible light Deposited 2021-01-25 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K,K40L,T51V,T53C,R58W,T29L,Y19W,Q4A | GOL GLYCEROL × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 2.11 Å R-free 0.264 |
| 7LHN Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal after exposure to visible light Deposited 2021-01-25 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K,K40L,T51V,T53C,R58W,T29L,Y19W,Q4A | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate , pH 4.6, EVAPORATION, temperature 298K
|
Resolution 2.11 Å R-free 0.264 |
| 7LHO Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal in the dark Deposited 2021-01-26 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A | GOL GLYCEROL × 1 RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6, evaporation, temperature 298K
|
Resolution 1.40 Å R-free 0.196 |
| 7LHO Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with all-trans-retinal in the dark Deposited 2021-01-26 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A | RET RETINAL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；30% PEG 4000, 0.1 M sodium acetate, 0.1 M ammonium acetate, pH 4.6, evaporation, temperature 298K
|
Resolution 1.40 Å R-free 0.196 |
| 7LSQ The Crystal Structure of Q108K:K40E:T53A:R58W:Q38F:Q4F:Y19W Mutant of HCRBPII Bound with LizFluor Chromophore Showing Excited State Intermolecular Proton Transfer Deposited 2021-02-18 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q4F, Y19W, Q38F, K40E, T53A, R58W, Q108K | ACT ACETATE ION × 1 ZFG 4-{5-[(2E)-but-2-en-2-yl]thiophen-2-yl}-N,N-dimethylaniline × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；298 K；Ammonium acetate, PEG 4000, Sodium acetate
|
Resolution 1.67 Å R-free 0.232 |
| 7LSQ The Crystal Structure of Q108K:K40E:T53A:R58W:Q38F:Q4F:Y19W Mutant of HCRBPII Bound with LizFluor Chromophore Showing Excited State Intermolecular Proton Transfer Deposited 2021-02-18 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q4F, Y19W, Q38F, K40E, T53A, R58W, Q108K | ACT ACETATE ION × 1 ZFG 4-{5-[(2E)-but-2-en-2-yl]thiophen-2-yl}-N,N-dimethylaniline × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；298 K；Ammonium acetate, PEG 4000, Sodium acetate
|
Resolution 1.67 Å R-free 0.232 |
| 7LSQ The Crystal Structure of Q108K:K40E:T53A:R58W:Q38F:Q4F:Y19W Mutant of HCRBPII Bound with LizFluor Chromophore Showing Excited State Intermolecular Proton Transfer Deposited 2021-02-18 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
|
Mutation：Q4F, Y19W, Q38F, K40E, T53A, R58W, Q108K | ACT ACETATE ION × 1 ZFG 4-{5-[(2E)-but-2-en-2-yl]thiophen-2-yl}-N,N-dimethylaniline × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；298 K；Ammonium acetate, PEG 4000, Sodium acetate
|
Resolution 1.67 Å R-free 0.232 |
| 7LSQ The Crystal Structure of Q108K:K40E:T53A:R58W:Q38F:Q4F:Y19W Mutant of HCRBPII Bound with LizFluor Chromophore Showing Excited State Intermolecular Proton Transfer Deposited 2021-02-18 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain D
2–134（133 aa）
|
Mutation：Q4F, Y19W, Q38F, K40E, T53A, R58W, Q108K | ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION；298 K；Ammonium acetate, PEG 4000, Sodium acetate
|
Resolution 1.67 Å R-free 0.232 |
| 7MFX The Crystal Structure of Q108K:K40H:T53A:R58L:Q38F:Q4F Mutant of HCRBPII Bound with FR1 Chromophore Showing Excited State Intermolecular Proton Transfer Deposited 2021-04-11 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q4F, Q38F, K40H, T53A, R58L, Q108K | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, sodium acetate, ammonium acetate
|
Resolution 1.59 Å R-free 0.232 |
| 7MFX The Crystal Structure of Q108K:K40H:T53A:R58L:Q38F:Q4F Mutant of HCRBPII Bound with FR1 Chromophore Showing Excited State Intermolecular Proton Transfer Deposited 2021-04-11 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q4F, Q38F, K40H, T53A, R58L, Q108K | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, sodium acetate, ammonium acetate
|
Resolution 1.59 Å R-free 0.232 |
| 7MFX The Crystal Structure of Q108K:K40H:T53A:R58L:Q38F:Q4F Mutant of HCRBPII Bound with FR1 Chromophore Showing Excited State Intermolecular Proton Transfer Deposited 2021-04-11 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
|
Mutation：Q4F, Q38F, K40H, T53A, R58L, Q108K | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 GOL GLYCEROL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, sodium acetate, ammonium acetate
|
Resolution 1.59 Å R-free 0.232 |
| 7MFX The Crystal Structure of Q108K:K40H:T53A:R58L:Q38F:Q4F Mutant of HCRBPII Bound with FR1 Chromophore Showing Excited State Intermolecular Proton Transfer Deposited 2021-04-11 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain D
2–134（133 aa）
|
Mutation：Q4F, Q38F, K40H, T53A, R58L, Q108K | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, sodium acetate, ammonium acetate
|
Resolution 1.59 Å R-free 0.232 |
| 7MFY The Crystal Structure of Q108K:K40L:T51V:T53S:R58W:Y19W:A33W:L117E Mutant of HCRBPII Bound with LizFluor Deposited 2021-04-12 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Y19W, A33W, K40L, T51V, T53S, R58W, Q108K, L117E | ACT ACETATE ION × 1 ZFG 4-{5-[(2E)-but-2-en-2-yl]thiophen-2-yl}-N,N-dimethylaniline × 1 GOL GLYCEROL × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, Ammonium acetate
|
Resolution 1.26 Å R-free 0.181 |
| 7MFZ The Crystal Structure of Domain-Swapped Trimer Q108K:K40D:T53A:R58L:Q38F:Q4F Mutant of HCRBPII Bound with LizFluor3 Chromophore Showing Excited State Intermolecular Proton Transfer Deposited 2021-04-12 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 3 PDB declaration: trimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
Chain C
2–134（133 aa）
|
Mutation：Q4F, Q38F, K40D, T53A, R58L, Q108K Mutation：Q4F, Q38F, K40D, T53A, R58L, Q108K Mutation：Q4F, Q38F, K40D, T53A, R58L, Q108K | ZFP 1-(4-{5-[(2E)-but-2-en-2-yl]thiophen-2-yl}phenyl)azetidine × 3 ACT ACETATE ION × 2 GOL GLYCEROL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate , ammonium acetate
|
Resolution 2.49 Å R-free 0.284 |
| 7UCN The Crystal Structure of Domain-Swapped Dimer Q108K:T51D:A28C:L36C:F57:H:R58 Mutant of hCRBPII with a Histidine Insertion in the Hinge Loop Region at 1.96 Angstrom Resolution Deposited 2022-03-16 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：A28C, L36C, T51D, Q109K Mutation：A28C, L36C, T51D, Q109K | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, ammonium acetate, sodium acetate
|
Resolution 1.96 Å R-free 0.268 |
| 7UCS The Crystal Structure of Domain-Swapped Dimer Q108K:T51D:A28C:L36C:F57:H:H:H:R58 Mutant of hCRBPII with Histidine Insertion in the Hinge Loop Region at 1.92 Angstrom Resolution Deposited 2022-03-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：A28C, L36C, T51D, Q111K Mutation：A28C, L36C, T51D, Q111K | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；Sodium acetate, PEG4000, ammonium acetate
|
Resolution 1.92 Å R-free 0.229 |
| 7UCT The Crystal Structure of Apo Domain-Swapped Dimer F57:H:H:H:H:H:H:R58 Mutant of HCRBPII with Histidine Insertion in the Hinge Loop Region at 2.5 Angstrom Resolution Deposited 2022-03-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：A28C, L36C, T51D, Q108K, Q114K Mutation：A28C, L36C, T51D, Q108K, Q114K | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, ammonium acetate
|
Resolution 2.52 Å R-free 0.238 |
| 7UCV The Crystal Structure of Apo Domain-Swapped Dimer Q108K:T51D:A28CL36C R58:H:H:H:N59 HCRBPII with Histidine Insertion in the Hinge Loop Region at 2.19 Angstrom Resolution Deposited 2022-03-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：A28C, L36C, T51D, Q111K Mutation：A28C, L36C, T51D, Q111K | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, sodium acetate, ammonium acetate
|
Resolution 2.19 Å R-free 0.266 |
| 7UCZ The Crystal Structure of Apo Monomer F57:H:H:H:H:H:H:R58 Mutant of HCRBPII with Histidine Insertion in the Hinge Loop Region at 1.1 Angstrom Resolution Deposited 2022-03-17 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；289 K；PEG 4000, sodium acetate, ammonium acetate
|
Resolution 1.08 Å R-free 0.213 |
| 7UCZ The Crystal Structure of Apo Monomer F57:H:H:H:H:H:H:R58 Mutant of HCRBPII with Histidine Insertion in the Hinge Loop Region at 1.1 Angstrom Resolution Deposited 2022-03-17 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；289 K；PEG 4000, sodium acetate, ammonium acetate
|
Resolution 1.08 Å R-free 0.213 |
| 7UD1 The Crystal Structure of Apo Monomer F57:H:H:H:R58 HCRBPII with Histidine Insertion in the Hinge Loop Region at 1.3 Angstrom Resolution Deposited 2022-03-17 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, Sodium acetate, ammonium acetate
|
Resolution 1.32 Å R-free 0.212 |
| 7UD1 The Crystal Structure of Apo Monomer F57:H:H:H:R58 HCRBPII with Histidine Insertion in the Hinge Loop Region at 1.3 Angstrom Resolution Deposited 2022-03-17 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Not recorded | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG 4000, Sodium acetate, ammonium acetate
|
Resolution 1.32 Å R-free 0.212 |
| 7UD3 The Crystal Structure of Domain-Swapped Dimer Q108K:T51D:A28C:L36C:F57:W:W:W:R58 Mutant of hCRBPII with a Histidine Insertion in the Hinge Loop Region at 2.36 Angstrom Resolution Deposited 2022-03-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain A
2–134（133 aa）
Chain B
2–134（133 aa）
|
Mutation：A28C, L36C, T51D, Q111K Mutation：A28C, L36C, T51D, Q111K | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；4000 PEG, Sodium acetate, ammonium acetate
|
Resolution 2.37 Å R-free 0.258 |
| 7UD3 The Crystal Structure of Domain-Swapped Dimer Q108K:T51D:A28C:L36C:F57:W:W:W:R58 Mutant of hCRBPII with a Histidine Insertion in the Hinge Loop Region at 2.36 Angstrom Resolution Deposited 2022-03-17 | Different construct Different mutation/modification Different oligomeric state Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein homooligomer Homooligomer；Protein × 2 PDB declaration: dimeric |
Chain C
2–134（133 aa）
Chain D
2–134（133 aa）
|
Mutation：A28C, L36C, T51D, Q111K Mutation：A28C, L36C, T51D, Q111K | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；4000 PEG, Sodium acetate, ammonium acetate
|
Resolution 2.37 Å R-free 0.258 |
| 8D6H Q108K:K40L:T51C:T53A:R58L:Q38F:Q4F mutant of hCRBPII bound to synthetic fluorophore CM1V after UV irradiation Deposited 2022-06-06 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51C, T53A, R58L, Q38F, Q4F | GOL GLYCEROL × 11 ACT ACETATE ION × 3 RH6 (2E)-3-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]prop-2-enal, bound form × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；293 K；PEG 4000, Ammonium Acetate, Sodium Acetate pH 4.0 - 4.8
|
Resolution 1.60 Å R-free 0.262 |
| 8D6L Q108K:K40L:T51C:T53A:R58L:Q38F:Q4F mutant of hCRBPII bound to synthetic fluorophore CM1V Deposited 2022-06-06 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T51C, T53A, R58L, Q38F, Q4F | GOL GLYCEROL × 4 RH6 (2E)-3-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]prop-2-enal, bound form × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；297 K；PEG 4000, Ammonium Acetate, Sodium Acetate, pH 4.0 - 4.8
|
Resolution 1.69 Å R-free 0.283 |
| 8D6N Q108K:K40L:T53A:R58L:Q38F:Q4F mutant of hCRBPII bound to synthetic fluorophore CM1V Deposited 2022-06-06 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K, K40L, T53A, R58L, Q38F, Q4F | ACT ACETATE ION × 3 RH6 (2E)-3-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]prop-2-enal, bound form × 1 GOL GLYCEROL × 7 MLA MALONIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；297 K；PEG 4000, Ammonium Acetate, Sodium Acetate, pH 4.0 - 4.8
|
Resolution 1.42 Å R-free 0.233 |
| 8DB2 Q108K:K40L:T51C:T53A:R58L:Q38F mutant of hCRBPII bound to synthetic fluorophore CM1V Deposited 2022-06-14 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K,K40L,T51C,T53A,R58L,Q38F | RH6 (2E)-3-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]prop-2-enal, bound form × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；297 K；PEG 4000, Ammonium Acetate, Sodium Acetate, pH 4.0 - 4.8
|
Resolution 1.50 Å R-free 0.268 |
| 8DN1 Q108K:K40L:T51C:T53A:R58L:Q38F:Q4F mutant of hCRBPII bound to synthetic fluorophore CM1V at pH 7.2 Deposited 2022-07-10 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | GOL GLYCEROL × 2 RH6 (2E)-3-[7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl]prop-2-enal, bound form × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；293 K；25% PEG 4000, ammonium acetate, sodium acetate pH 4.0 - 4.8
|
Resolution 1.32 Å R-free 0.217 |
| 8VZX Q108K:K40L:T53A:R58F mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different mutation/modification Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T53A:R58F | ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；ammonium acetate, sodium acetate, PEG4000
|
Resolution 1.47 Å R-free 0.263 |
| 8VZX Q108K:K40L:T53A:R58F mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different mutation/modification Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T53A:R58F | ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；ammonium acetate, sodium acetate, PEG4000
|
Resolution 1.47 Å R-free 0.263 |
| 8VZX Q108K:K40L:T53A:R58F mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different mutation/modification Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
|
Mutation：Q108K:K40L:T53A:R58F | ACT ACETATE ION × 1 A1AEQ (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；ammonium acetate, sodium acetate, PEG4000
|
Resolution 1.47 Å R-free 0.263 |
| 8VZX Q108K:K40L:T53A:R58F mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different mutation/modification Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain D
2–134（133 aa）
|
Mutation：Q108K:K40L:T53A:R58F | ACT ACETATE ION × 1 A1AEQ (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；ammonium acetate, sodium acetate, PEG4000
|
Resolution 1.47 Å R-free 0.263 |
| 8VZY Q108K:K40L:T51V:T53S:R58Y mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different mutation/modification Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58Y | A1AEQ (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；PEG4000, ammonium acetate, sodium acetate
|
Resolution 1.34 Å R-free 0.282 |
| 8VZY Q108K:K40L:T51V:T53S:R58Y mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58Y | No recorded non-water small molecule |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；PEG4000, ammonium acetate, sodium acetate
|
Resolution 1.34 Å R-free 0.282 |
| 8VZZ Q108K:K40L:T51V:T53S:Y19W:R58W mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:Y19W:R58W | A1AEQ (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal × 1 ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；PEG4000, ammonium acetate, sodium acetate
|
Resolution 1.22 Å R-free 0.183 |
| 8VZZ Q108K:K40L:T51V:T53S:Y19W:R58W mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:Y19W:R58W | A1AEQ (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal × 1 ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；PEG4000, ammonium acetate, sodium acetate
|
Resolution 1.22 Å R-free 0.183 |
| 8W00 Q108K:K40L:T51V:T53S:Y19W:R58W:L117E mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different mutation/modification Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:Y19W:R58W:L117E | A1AEQ (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；PEG4000, sodium acetate, ammonium aceate
|
Resolution 1.23 Å R-free 0.185 |
| 8W00 Q108K:K40L:T51V:T53S:Y19W:R58W:L117E mutant of hCRBPII bound to synthetic fluorophore TD-1V Deposited 2024-02-13 | Different mutation/modification Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:Y19W:R58W:L117E | A1AEQ (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；295 K；PEG4000, sodium acetate, ammonium aceate
|
Resolution 1.23 Å R-free 0.185 |
| 9D8M Q108K:K40L:T51V:T53C:R58W:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V fluorophore in the dark state at pH 4 Deposited 2024-08-19 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58W:Y19W:Q38L:Q4A:T29L | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 ACY ACETIC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.20 Å R-free 0.204 |
| 9D8M Q108K:K40L:T51V:T53C:R58W:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V fluorophore in the dark state at pH 4 Deposited 2024-08-19 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58W:Y19W:Q38L:Q4A:T29L | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 ACY ACETIC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.20 Å R-free 0.204 |
| 9D8N Q108K:K40L:T51V:T53C:R58W:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V and irradiated with UV light at pH 4 Deposited 2024-08-19 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58W:Y19W:Q38L:Q4A:T29L | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 GOL GLYCEROL × 1 ACY ACETIC ACID × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.30 Å R-free 0.224 |
| 9D8N Q108K:K40L:T51V:T53C:R58W:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V and irradiated with UV light at pH 4 Deposited 2024-08-19 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58W:Y19W:Q38L:Q4A:T29L | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 GOL GLYCEROL × 1 ACY ACETIC ACID × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.30 Å R-free 0.224 |
| 9D8O Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L mutant of hCRBPII in complex with FR1V in the dark state at pH 3.0 Deposited 2024-08-19 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L | ACT ACETATE ION × 1 GOL GLYCEROL × 3 ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.32 Å R-free 0.237 |
| 9D8O Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L mutant of hCRBPII in complex with FR1V in the dark state at pH 3.0 Deposited 2024-08-19 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L | ACT ACETATE ION × 1 GOL GLYCEROL × 1 ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.32 Å R-free 0.237 |
| 9DDU Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V and irradiated with UV light at pH 3.0 Deposited 2024-08-28 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Not recorded | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 ACY ACETIC ACID × 1 GOL GLYCEROL × 5 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.60 Å R-free 0.218 |
| 9DDU Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V and irradiated with UV light at pH 3.0 Deposited 2024-08-28 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 ACY ACETIC ACID × 2 GOL GLYCEROL × 3 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.60 Å R-free 0.218 |
| 9DE1 Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V in the dark at pH 6.0 Deposited 2024-08-28 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Not recorded | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 ACT ACETATE ION × 1 GOL GLYCEROL × 2 MLI MALONATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；25% PEG4000, 100 mM ammonium acetate, 100 mM sodium acetate, pH 4.0-4.8
|
Resolution 1.40 Å R-free 0.209 |
| 9DE1 Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V in the dark at pH 6.0 Deposited 2024-08-28 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 MLI MALONATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；25% PEG4000, 100 mM ammonium acetate, 100 mM sodium acetate, pH 4.0-4.8
|
Resolution 1.40 Å R-free 0.209 |
| 9DF1 Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V and irradiated with UV light at pH 7.6 Deposited 2024-08-29 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Not recorded | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 ACY ACETIC ACID × 1 MLA MALONIC ACID × 1 GOL GLYCEROL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.52 Å R-free 0.232 |
| 9DF1 Q108K:K40L:T51V:T53C:R58Y:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V and irradiated with UV light at pH 7.6 Deposited 2024-08-29 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Not recorded | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 MLA MALONIC ACID × 3 GOL GLYCEROL × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.52 Å R-free 0.232 |
| 9DF8 Q108K:K40L:T51V:T53C:R58A:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V and irradiated with UV light at pH 3.0 Deposited 2024-08-29 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58A:Y19W:Q38L:Q4A:T29L | ACT ACETATE ION × 2 GOL GLYCEROL × 3 ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；25% PEG4000, 100 mM ammonium acetate, 100 mM sodium acetate, pH 4.0-4.8
|
Resolution 1.78 Å R-free 0.229 |
| 9DF8 Q108K:K40L:T51V:T53C:R58A:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V and irradiated with UV light at pH 3.0 Deposited 2024-08-29 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58A:Y19W:Q38L:Q4A:T29L | ACT ACETATE ION × 1 GOL GLYCEROL × 2 ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；25% PEG4000, 100 mM ammonium acetate, 100 mM sodium acetate, pH 4.0-4.8
|
Resolution 1.78 Å R-free 0.229 |
| 9DFB Q108K:K40L:T51V:T53C:R58A:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V in the dark at pH 3.0 Deposited 2024-08-29 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58A:Y19W:Q38L:Q4A:T29L | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 EDO 1,2-ETHANEDIOL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.71 Å R-free 0.252 |
| 9DFB Q108K:K40L:T51V:T53C:R58A:Y19W:Q38L:Q4A:T29L mutant of hCRBPII bound to FR1V in the dark at pH 3.0 Deposited 2024-08-29 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53C:R58A:Y19W:Q38L:Q4A:T29L | ZFJ (4aP)-N,N-diethyl-9,9-dimethyl-7-[(1E)-prop-1-en-1-yl]-9H-fluoren-2-amine × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0-4.8
|
Resolution 1.71 Å R-free 0.252 |
| 9O3M K40F mutant of hCRBPII bound to fentanyl Deposited 2025-04-07 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：K40F | ACT ACETATE ION × 1 GOL GLYCEROL × 3 7V7 N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0 - 4.8
|
Resolution 1.42 Å R-free 0.231 |
| 9O3M K40F mutant of hCRBPII bound to fentanyl Deposited 2025-04-07 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：K40F | GOL GLYCEROL × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；pH 4；298 K；PEG4000, ammonium acetate, sodium acetate, pH 4.0 - 4.8
|
Resolution 1.42 Å R-free 0.231 |
| 9PN1 Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with 15-cis-retinal Deposited 2025-07-18 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:Y19W:T53C:R58W:T29L:Q4A | No recorded non-water small molecule | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.26 Å R-free 0.221 |
| 9PN1 Crystal structure of Q108K:K40L:T51V:T53C:R58W:T29L:Y19W:Q4A mutant of cellular retinol binding protein II complex with 15-cis-retinal Deposited 2025-07-18 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:Y19W:T53C:R58W:T29L:Q4A | No recorded non-water small molecule | X-RAY DIFFRACTION mmCIF provides none of the parsed conditions | Resolution 1.26 Å R-free 0.221 |
| 9PSV Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-7 Deposited 2025-07-27 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | A1CKU (2E)-3-[5-(dimethylamino)thiophen-2-yl]but-2-enal × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.51 Å R-free 0.231 |
| 9PSV Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-7 Deposited 2025-07-27 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | A1CKU (2E)-3-[5-(dimethylamino)thiophen-2-yl]but-2-enal × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.51 Å R-free 0.231 |
| 9PSW Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-2 Deposited 2025-07-27 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | A1CKV (2E)-3-{5-[4-(azetidin-1-yl)phenyl]thiophen-2-yl}but-2-enal × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.61 Å R-free 0.198 |
| 9PSX Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-3 Deposited 2025-07-27 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | A1CKW (2E)-3-[5-(4-methoxyphenyl)thiophen-2-yl]but-2-enal × 1 ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.29 Å R-free 0.186 |
| 9PSY Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-1 Deposited 2025-07-27 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117 | A1CKX (2E)-3-(5-phenylthiophen-2-yl)but-2-enal × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.62 Å R-free 0.245 |
| 9PSY Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-1 Deposited 2025-07-27 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117 | A1CKX (2E)-3-(5-phenylthiophen-2-yl)but-2-enal × 1 ACT ACETATE ION × 2 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.62 Å R-free 0.245 |
| 9PT0 Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-8 Deposited 2025-07-27 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | A1CKZ (2E)-3-[5'-(dimethylamino)[2,2'-bithiophen]-5-yl]but-2-enal × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.64 Å R-free 0.223 |
| 9PT1 Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-10 Deposited 2025-07-27 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | A1CK0 (2E)-3-{4-[5-(dimethylamino)thiophen-2-yl]phenyl}but-2-enal × 1 ACT ACETATE ION × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.48 Å R-free 0.195 |
| 9PT3 Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-9 Deposited 2025-07-27 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 1 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain A
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | ACT ACETATE ION × 1 A1CK1 (2E)-3-[4'-(dimethylamino)[1,1'-biphenyl]-4-yl]but-2-enal × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.79 Å R-free 0.255 |
| 9PT3 Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-9 Deposited 2025-07-27 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 2 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain B
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | ACT ACETATE ION × 1 A1CK1 (2E)-3-[4'-(dimethylamino)[1,1'-biphenyl]-4-yl]but-2-enal × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.79 Å R-free 0.255 |
| 9PT3 Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-9 Deposited 2025-07-27 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 3 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain C
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | ACT ACETATE ION × 1 A1CK1 (2E)-3-[4'-(dimethylamino)[1,1'-biphenyl]-4-yl]but-2-enal × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.79 Å R-free 0.255 |
| 9PT3 Q108K:K40L:T51V:T53S:R58W:Y19W:L117E mutant of hCRBPII bound to fluorophore TD-1V-9 Deposited 2025-07-27 | Different mutation/modification Different ligand/ion Different experimental conditions Different structure-quality metrics | Assembly 4 Protein monomer Monomer；Protein × 1 PDB declaration: monomeric |
Chain D
2–134（133 aa）
|
Mutation：Q108K:K40L:T51V:T53S:R58W:Y19W:L117E | ACT ACETATE ION × 1 A1CK1 (2E)-3-[4'-(dimethylamino)[1,1'-biphenyl]-4-yl]but-2-enal × 1 |
X-RAY DIFFRACTION
X-ray crystallization conditions
VAPOR DIFFUSION, HANGING DROP；298 K；PEG4000, ammonium acetate, 100 mM sodium acetate, pH 4.0 - 4.8
|
Resolution 1.79 Å R-free 0.255 |
101 other PDB entries and 199 assemblies. Open the comparison page and filter oligomeric states
View Construct and Data Evidence
| UniProt name | RET2_HUMAN |
| Isoform | — |
| PDB entities | 1 |
| Chains and sequence ranges | Author chain A； PDBConstruct 1–133； UniProt 2–134 Author chain B； PDBConstruct 1–133； UniProt 2–134 |
